KuyiniI-Andrographis Paniculata Extract ?
I-Andrographis paniculata, eyaziwa nangokuthi “injabulo yesikhathi esisodwa” kanye “notshani obubabayo”, iyisitshalo saminyaka yonke esikhula ngamakhambi somndeni wakwa-Acanthaceae. Sivela eNingizimu Asia njengeNdiya neSri Lanka, futhi manje sisakazeke kabanzi ezindaweni ezinomswakama nezishisayo njengeGuangdong neFujian eShayina. Lesi sitshalo sonke sinambitheka ngokubaba kakhulu, sinesiqu esiyisikwele, amaqabunga aphambene, kanye nesikhathi sokuqhakaza kusukela ngo-Agasti-Septhemba. Imithi yendabuko yaseShayina isebenzisa imiphumela yayo yokususa ukushisa nokuhlanza, ukupholisa igazi nokunciphisa ukuvuvukala ukwelapha umkhuhlane, umkhuhlane, uhudo, izilonda kanye nokulunywa yinyoka. Imboni yanamuhla ikhipha izithako ezisebenzayo eziqwini nasemaqabungeni ngokusebenzisa i-CO₂ extraction ephezulu kanye nobuchwepheshe be-bio-enzyme hydrolysis ukwenza impuphu ejwayelekile enokuqukethwe kwe-andrographolide okungu-8%-98%, ikhuthaza ukuthuthukiswa kwayo kusuka emithini yesintu yamakhambi kuya ezintweni zokusetshenziswa zomhlaba wonke.
Izithako ezisebenzayo eziyinhloko zeI-Andrographis Paniculata Eiziqephuziyi-diterpenoid lactone compounds, ezibalelwa ku-2%-5%24, ikakhulukazi ezifaka:
1. I-Andrographolide:ifomula yama-molecule C₂₀H₃₀O₅, ebalelwa ku-30%-50%, iyisithako esiyinhloko esisebenzayo sokulwa namagciwane kanye nokulwa nokuvuvukala.
2. I-Dehydroandrogenographolide:ifomula yama-molecule C₂₀H₂₈O₄, iphuzu lokuncibilika elingu-204℃, elinomsebenzi obalulekile wokulwa nomdlavuza.
3. 14-Deoxyandrographolide:ifomula yama-molecule C₂₀H₃₀O₄, esebenza kahle kakhulu ekulweni ne-leptospirosis.
4. I-Neoandrogenolide:ifomula yama-molecule C₂₆H₄₀O₈, ukuncibilika kwamanzi okuhle, okufanelekela amalungiselelo omlomo.
Ngaphezu kwalokho, ama-flavonoid, ama-phenolic acid kanye nezingxenye zamafutha eziguquguqukayo zithuthukisa ngokubambisana imisebenzi yokulwa ne-antioxidant kanye ne-immunomodulatory.
Yiziphi Izinzuzo ZazoI-Andrographis Paniculata Extract ?
1. Ukuguqulwa Kwamasosha omzimba kanye Nokulwa Nokutheleleka
Ilwa namagciwane kanye ne-antiviral: I-Andrographolide inesilinganiso sokuvimbela esingaphezu kuka-90% ku-Staphylococcus aureus kanye ne-Shigella dysenteriae, futhi ukusebenza kwayo ekwelapheni i-bacillary dysenteriae kufana ne-chloramphenicol. I-extract yayo yamanzi inganciphisa ukwanda kwe-influenza ngo-30% futhi ifinyeze inkambo yemikhuhlane ngo-50%.
Ukuthuthukiswa Kwamasosha omzimba: Ngokusebenzisa ama-macrophage nama-T lymphocyte, kungandisa izinga lama-CD4⁺ lymphocyte ezigulini ezine-HIV (idatha yezokwelapha: 405→501/mm³, p=0.002).
2. Ukuvinjelwa Kokulwa Nesimila Ne-Angiogenesis
I-anti-tumor eqondile: I-Dehydroandrogenolide ingavimbela ukukhula kwezimila ezitshalwe kabusha ze-W256 futhi ivimbele ukwanda kwamaseli omdlavuza ngendlela encike kumthamo.
I-Anti-angiogenesis: I-Andrographolide ivimba i-tumor angiogenesis ngokunciphisa ukubonakaliswa kwe-VEGFR2 futhi ivimbele indlela yokubonisana ye-ERK/p38, nge-IC₅₀ engu-100-200μM.
3. Ukwakheka Kwemetabolism Nokuvikelwa Kwezitho
Ukuvikelwa kwesibindi kanye nokunciphisa amafutha: I-Andrographolide igcina amazinga e-glutathione futhi yehlisa i-malondialdehyde (MDA) kumodeli yokulimala kwesibindi ye-carbon tetrachloride ngo-40%, okungcono kune-silymarin.
Ukuvikelwa kwenhliziyo nemithambo yegazi: Kulawula ibhalansi ye-nitric oxide/endothelin, kubambezele i-atherosclerosis, futhi kunciphisa amazinga e-lipid egazini konogwaja abahlolwayo.
4. Ilwa Nokuvuvukala Ne-Antioxidant
I-extract yamanzi yesiqu inekhono elinamandla kakhulu lokumba ama-free radicals (IC₅₀=4.42μg/mL), esebenza kahle ngokuphindwe kane kune-antioxidant yokwenziwa futhi ifanele izifo zokuvuvukala ezingamahlalakhona.
Yiziphi Izicelo ZazoI-Andrographis Paniculata Extract ?
1. Ukwelashwa Kwezokwelapha Nokwelashwa
Imithi yokulwa nokutheleleka: esetshenziselwa uhudo olubangelwa amagciwane, umjovo we-pneumonia kanye nokulungiselela ngomlomo i-pharyngitis, ngezinga lokuphulukiswa kwezokwelapha elingaphezu kuka-85%.
Imithi elwa nomdlavuza: I-Andrographolide derivative “Andrographine” isingene ezivivinyweni zezokwelapha zeSigaba sesiBili se-leukemia kanye nezimila eziqinile.
Ukuphathwa kwezifo ezingamahlalakhona: ukwelashwa okungeziwe kwe-diabetic retinopathy (0.5-2mg/kg/ngosuku) kanye ne-rheumatoid arthritis (1-3mg/kg/ngosuku).
2. Ukufuya Izilwane Nokuzala Okuluhlaza
Amanye ama-antibiotic: Izithasiselo zokudla ze-Andrographis paniculata ezihlanganisiwe zinciphisa izinga lohudo lwamachwane ezingulube futhi zandise izinga lokusinda kwama-broiler; ukwengeza u-4% wokukhipha ekudleni kwe-carp, izinga lokukhuluphala lifinyelela ku-155.1%, kanti izinga lokuguqulwa kokudla lilungiswa libe ngu-1.11.
Ukuvimbela nokulawula izifo: Umjovo we-Andrographis paniculata welapha i-pig pneumonia kanye ne-enteritis, ngesilinganiso sokwelapha esingu-90% kanye nesilinganiso sokufa esingu-10%.
3. Ukudla Okunempilo Namakhemikhali Ansuku Zonke
Ukudla okusebenzayo:I-Andrographis paniculataisithakoAma-capsule (200mg ngosuku) aqaliswa emakethe yaseYurophu naseMelika ukuze kulawulwe amasosha omzimba kanye nokuvimbela umkhuhlane.
Imikhiqizo yokunakekela isikhumba: Faka kuma-anti-inflammatory essences kanye nama-sunscreen ukuze unciphise umonakalo we-UV kanye nokubomvu kwesikhumba esibucayi.
4. Ukuphumelela Emasimini Akhulayo
Imithi yokulwa ne-angiogenic: Ukuthuthukiswa kwemithi eqondiwe yezimila kanye ne-retinopathy yesifo sikashukela sekuyindlela ebalulekile yebhayoloji yokwenziwa.
Ukunakekelwa kwezilwane ezifuywayo: Izithako zokulwa nokuvuvukala kanye nezokulwa namasosha omzimba ezinja namakati ziqaliswa emakethe yaseNyakatho Melika, ngesilinganiso sokukhula saminyaka yonke esingu-35%.
Ukuze uthole ulwazi olwengeziwe, sicela uxhumane nathi:
Igama: uNora
Ucingo/i-whatsapp: +86 15594821525
Email:nora@lfherb.com
Isikhathi sokuthunyelwe: Okthoba-20-2026