Yintoni iI-Andrographis Paniculata Extract ?
I-Andrographis paniculata, ekwaziwa ngokuba “lulonwabo lwexesha elinye” kunye “nengca ekrakra”, sisityalo semifuno esikhula minyaka le sosapho lwe-Acanthaceae. Sivela eMzantsi Asia njengeIndiya neSri Lanka, kwaye ngoku sisasazeke kakhulu kwiindawo ezifumileyo nezishushu ezifana neGuangdong kunye neFujian eTshayina. Isityalo sonke sinambitheka kabuhlungu kakhulu, sinesiqu esisikwere, amagqabi achaseneyo, kunye nexesha lokudubula kweentyatyambo ukusuka ku-Agasti ukuya kuSeptemba. Amayeza emveli aseTshayina asebenzisa iziphumo zawo zokususa ubushushu kunye nokukhupha iintsholongwane, ukupholisa igazi kunye nokunciphisa ukudumba ukunyanga umkhuhlane, umkhuhlane, isisu segazi, izilonda kunye nokulunywa yinyoka. Ishishini lanamhlanje likhupha izithako ezisebenzayo kwiziqu kunye namagqabi ngokusebenzisa i-CO₂ extraction ephezulu kunye netekhnoloji ye-bio-enzyme hydrolysis ukwenza iipowders ezisemgangathweni ezinomxholo we-andrographolide we-8%-98%, ikhuthaza ukuphuculwa kwayo ukusuka kumayeza esintu ukuya kwizixhobo eziluhlaza zamazwe ngamazwe.
Izithako eziphambili ezisebenzayo zeI-Andrographis Paniculata Eizicatshulwaziikhompawundi ze-diterpenoid lactone, ezibalelwa kwi-2%-5%24, ikakhulu ziquka:
1. I-Andrographolide:Ifomula yemolekyuli i-C₂₀H₃₀O₅, ebalelwa kwi-30%-50%, yeyona nto iphambili esebenzayo ekulweni neentsholongwane kunye nokulwa nokuvuvukala.
2. I-Dehydroandrogenographolide:Ifomula yemolekyuli C₂₀H₂₈O₄, iqondo lokunyibilika elingama-204℃, kunye nomsebenzi obalulekileyo wokulwa nethumba.
3. I-14-Deoxyandrographolide:ifomula yemolekyuli C₂₀H₃₀O₄, esebenza kakuhle kakhulu kwi-leptospirosis.
4. I-Neoandrogenolide:Ifomula yemolekyuli C₂₆H₄₀O₈, ukunyibilika kwamanzi okulungileyo, okufanelekileyo ekulungiseleleni ngomlomo.
Ukongeza, ii-flavonoids, ii-phenolic acids kunye neenxalenye zeoyile eziguquguqukayo ziphucula ngokudibeneyo imisebenzi ye-antioxidant kunye ne-immunomodulatory.
Zithini iingenelo zeI-Andrographis Paniculata Extract ?
1. Ukuguqulwa kwamasosha omzimba kunye nokulwa nosulelo
Ilwa neentsholongwane kunye ne-antiviral: I-Andrographolide inezinga lokuthintela elingaphezulu kwe-90% kwi-Staphylococcus aureus kunye ne-Shigella dysenteriae, kwaye ukusebenza kwayo ekunyangeni i-bacillary dysenteriae kuyafana ne-chloramphenicol. I-extract yayo yamanzi inokunciphisa ukwanda kwe-influenza ngama-30% kwaye inciphise ixesha lomkhuhlane ngama-50%.
Ukuphucula amasosha omzimba: Ngokusebenzisa ii-macrophages kunye nee-T lymphocytes, kunokunyusa izinga le-CD4⁺ lymphocytes kwizigulana ezine-HIV (idatha yeklinikhi: 405→501/mm³, p=0.002).
2. Ukuthintelwa kwe-Anti-Tumor kunye ne-Angiogenesis
I-anti-tumor ngqo: I-Dehydroandrographolide inokuthintela ukukhula kwee-tumor ezitshalwe ngokutsha ze-W256 kwaye ithintele ukwanda kweeseli zomhlaza ngendlela exhomekeke kwidosi.
I-Anti-angiogenesis: I-Andrographolide ithintela i-tumor angiogenesis ngokunciphisa ukubonakaliswa kwe-VEGFR2 kwaye ithintele indlela yokubonisa ye-ERK/p38, nge-IC₅₀ ye-100-200μM.
3. I-Metabolism kunye noKhuseleko lwamalungu omzimba
Ukukhuselwa kwesibindi kunye nokunciphisa amafutha: I-Andrographolide igcina amanqanaba e-glutathione kwaye inciphisa i-malondialdehyde (MDA) kwimodeli yokulimala kwesibindi se-carbon tetrachloride ngama-40%, nto leyo ingcono kune-silymarin.
Ukukhuselwa kwentliziyo nemithambo yegazi: Kulawula ibhalansi ye-nitric oxide/endothelin, kulibazise i-atherosclerosis, kwaye kunciphisa amanqanaba e-lipid egazini kwiimbila ezivavanyiweyo.
4. Ilwa nokudumba kunye ne-antioxidant
Isicatshulwa samanzi esikwisiqu sinamandla amakhulu okususa ii-free radicals (IC₅₀=4.42μg/mL), esisebenza ngokuphindwe kane kunee-antioxidant zokwenziwa kwaye sifanelekile kwizifo ezingapheliyo zokudumba.
Zithini Izicelo ZaloI-Andrographis Paniculata Extract ?
1. Amayeza kunye noNyango lwezonyango
Amayeza okulwa nosulelo: asetyenziselwa isifo segazi esibangelwa ziintsholongwane, inaliti ye-pneumonia kunye namalungiselelo omlomo e-pharyngitis, kunye nezinga lokunyanga elingaphezulu kwama-85%.
Amayeza ajoliswe ekulweni nethumba: I-Andrographolide derivative "Andrographine" ingenele uvavanyo lweklinikhi lweSigaba sesiBini se-leukemia kunye nethumba eliqinileyo.
Ulawulo lwezifo ezingapheliyo: unyango oluncedisayo lwe-diabetesic retinopathy (0.5-2mg/kg/ngosuku) kunye ne-rheumatoid arthritis (1-3mg/kg/ngosuku).
2. Ukufuya Izilwanyana Nokufuya Okuluhlaza
Ezinye iindlela zokwelapha iintsholongwane: Izithako zokutya ze-Andrographis paniculata ezidityanisiweyo zinciphisa izinga lorhudo lweehagu ezincinci kwaye zonyusa izinga lokusinda kweenkukhu; ukongeza i-4% yesicatshulwa kwi-carp feed, izinga lokutyeba lifikelela kwi-155.1%, kwaye izinga lokuguqulwa kokutya liphuculwa libe yi-1.11.
Ukuthintela nokulawula izifo: Inaliti ye-Andrographis paniculata inyanga i-pigeon pneumonia kunye ne-enteritis, ngesantya sokuphiliswa se-90% kunye nesantya sokufa se-10%.
3. Ukutya Okunempilo Neekhemikhali Zemihla Ngemihla
Ukutya okusebenzayo:I-Andrographis paniculataisicatshulwaIikhaphu (200mg ngosuku) ziqaliswa kwiimarike zaseYurophu naseMelika ukuze kulawulwe amajoni omzimba kunye nokuthintela umkhuhlane.
Iimveliso zokhathalelo lolusu: Yongeza kwizinto ezilwa nokuvuvukala kunye nezithambiso zelanga ukuze unciphise umonakalo we-UV kunye nokubomvu kolusu olubuthathaka.
4. Ukuphumelela Kwimimandla Ekhulayo
Amayeza okulwa ne-angiogenic: Uphuhliso lwamayeza ajoliswe kuwo eethumba kunye ne-diabetic retinopathy lube yindlela ephambili yebhayoloji yokwenziwa.
Ukhathalelo lwezilwanyana zasekhaya: Izongezo zokulwa nokuvuvukala kunye nezokunciphisa umzimba ezisetyenziswa kwizinja nakwiikati ziqalisiwe kwimarike yaseMntla Melika, kunye nokukhula konyaka kwe-35%.
Ukuze ufumane ulwazi oluthe kratya, nceda unxibelelane:
Igama: uNora
Umnxeba/i-whatsapp: +86 15594821525
Email:nora@lfherb.com
Ixesha lokuthumela: Okthobha-20-2026