He aha ka meaʻO ka ʻāpana Andrographis Paniculata ?
ʻO Andrographis paniculata, i ʻike ʻia hoʻi ʻo "hoʻokahi manawa hauʻoli" a me "mauʻu ʻawaʻawa", he mea kanu herbaceous makahiki ia o ka ʻohana Acanthaceae. He ʻōiwi ia no ʻAsia Hema e like me India a me Sri Lanka, a ua laha nui ʻia i kēia manawa ma nā wahi pulu a wela e like me Guangdong a me Fujian ma Kina. ʻO ka ʻono o ka mea kanu holoʻokoʻa he ʻawaʻawa loa, me kahi kumu huinaha, nā lau ʻē aʻe, a me ka wā pua o ʻAukake-Kepakemapa. Hoʻohana ka lāʻau lapaʻau kuʻuna Kina i kona hopena o ka hoʻomaʻemaʻe ʻana i ka wela a me ka detoxifying, hoʻomaʻalili i ke koko a me ka hōʻemi ʻana i ka pehu e mālama i ke anu, ke kuni, ka maʻi dysentery, nā ʻeha a me nā nahu nahesa. Hoʻopuka ka ʻoihana hou i nā mea hana mai nā kumu a me nā lau ma o ka extraction CO₂ supercritical a me ka ʻenehana hydrolysis bio-enzymatic e hana i nā pauka maʻamau me ka nui o ka andrographolide o 8%-98%, e paipai ana i kona hoʻonui ʻana mai ka lāʻau lapaʻau lāʻau kuʻuna i nā mea maka honua.
ʻO nā mea hana nui oʻAndrographis Paniculata Enā ʻāpanahe mau hui diterpenoid lactone, e helu ana no 2%-5%24, ʻo ia hoʻi:
1. ʻAndrographolide:ʻO ke ʻano molekala C₂₀H₃₀O₅, e helu ana i 30%-50%, ʻo ia ka mea hana nui no ka antibacterial a me ka anti-inflammatory.
2. ʻO ka Dehydroandrographolide:ʻO ke ʻano molekala C₂₀H₂₈O₄, kiko heheʻe 204 ℃, me ka hana anti-tumor koʻikoʻi.
3. 14-Deoxyandrographolide:ʻO ke ʻano molekala C₂₀H₃₀O₄, me ka hopena koʻikoʻi e kūʻē i ka leptospirosis.
4. ʻO Neoandrographolide:ʻO ke ʻano molekala C₂₆H₄₀O₈, maikaʻi ka hoʻoheheʻe ʻia ʻana i ka wai, kūpono no nā hoʻomākaukau waha.
Eia kekahi, ʻo nā flavonoids, nā waikawa phenolic a me nā ʻāpana aila volatile e hoʻoikaika i nā hana antioxidant a me nā hana immunomodulatory.
He aha nā pono oʻO ka ʻāpana Andrographis Paniculata ?
1. Ka Immunomodulation a me ka Anti-Infection
Antibacterial a me antiviral: ʻOi aku ka nui o ka pale ʻana o Andrographolide ma mua o 90% ma Staphylococcus aureus a me Shigella dysenteriae, a ʻo kona pono lapaʻau i ka mālama ʻana i ka maʻi dysentery bacillary ua like ia me ka chloramphenicol. Hiki i kāna wai hoʻoheheʻe ke hōʻemi i ka nui o ka maʻi influenza ma 30% a hoʻopōkole i ke ala o ke anu ma 50%.
Hoʻonui ʻana i ka pale ʻana i ka maʻi: Ma ka hoʻoulu ʻana i nā macrophages a me nā T lymphocytes, hiki iā ia ke hoʻonui i ka pae o nā CD4⁺ lymphocytes i nā poʻe maʻi HIV (ʻikepili lapaʻau: 405→501/mm³, p=0.002).
2. Ka pale ʻana i ka puʻupuʻu a me ka angiogenesis
Kūʻē pololei i ka puʻupuʻu: Hiki iā Dehydroandrographolide ke kāohi i ka ulu ʻana o nā puʻupuʻu i hoʻoili ʻia ʻo W256 a kāohi i ka hoʻonui ʻia ʻana o nā cell cancer ma ke ʻano e hilinaʻi ʻia ana i ka lāʻau.
Anti-angiogenesis: Hoʻopilikia ʻo Andrographolide i ka angiogenesis tumor ma o ka hoʻohaʻahaʻa ʻana i ka hōʻike ʻana o VEGFR2 a me ke kāohi ʻana i ke ala hōʻailona ERK/p38, me ka IC₅₀ o 100-200μM.
3. Ka Metabolism a me ka Palekana o nā ʻŌkana
Ka pale ʻana i ke akepaʻa a me ka hoʻēmi ʻana i ka lipid: Mālama ʻo Andrographolide i nā pae glutathione a hoʻēmi i ka malondialdehyde (MDA) i loko o ke kumu hoʻohālike hōʻeha akepaʻa carbon tetrachloride ma 40%, ʻoi aku ka maikaʻi ma mua o silymarin.
Ka palekana o ka naʻau: Hoʻoponopono i ke kaulike nitric oxide/endothelin, hoʻopaneʻe i ka atherosclerosis, a hoʻemi i nā pae lipid koko i nā lāpaki hoʻokolohua.
4. Anti-Inflammatory a me Antioxidant
ʻO ka wai i hoʻokahe ʻia mai ke kumu o ke kumu ka mea hiki ke hoʻopau i nā radical manuahi (IC₅₀=4.42μg/mL), he 4 manawa ʻoi aku ka maikaʻi ma mua o nā antioxidants synthetic a kūpono hoʻi no nā maʻi mumū mau loa.
He aha nā noi oʻO ka ʻāpana Andrographis Paniculata ?
1. Lāʻau Lapaʻau a me ka Lapaʻau Lapaʻau
Nā lāʻau lapaʻau anti-infective: hoʻohana ʻia no ka maʻi bacterial dysentery, pneumonia injection a me nā hoʻomākaukau waha no ka pharyngitis, me ka helu ho'ōla lapaʻau ma luna o 85%.
Nā lāʻau lapaʻau anti-tumor i hoʻolālā ʻia: Ua komo ka Andrographolide derivative "Andrographine" i nā hoʻokolohua lapaʻau Phase II no ka leukemia a me nā ʻōpū paʻa.
Ka mālama ʻana i nā maʻi maʻi mau: ka lāʻau lapaʻau kōkua no ka retinopathy diabetic (0.5-2mg/kg/lā) a me ka rheumatoid arthritis (1-3mg/kg/lā).
2. Ka mahi holoholona a me ka hoʻoulu ʻana i ka ʻōmaʻomaʻo
ʻO nā lāʻau antibiotic ʻē aʻe: Hoʻemi nā mea hoʻohui hānai Andrographis paniculata i ka nui o ka maʻi diarrhea o nā puaʻa a hoʻonui i ka nui o ke ola o nā broilers; me ka hoʻohui ʻana i ka 4% extract i ka hānai carp, hiki i ka nui o ke kaumaha i 155.1%, a ua hoʻonui ʻia ka nui o ka hoʻololi ʻana i ka hānai i 1.11.
Ka pale ʻana a me ka kaohi ʻana i nā maʻi: Hoʻōla ka inikini Andrographis paniculata i ka maʻi niumonia puaʻa a me ka enteritis, me ka helu ho'ōla o 90% a me ka helu make o 10%.
3. Meaʻai Ola Kino a me nā Kemika o kēlā me kēia lā
Meaʻai hana:ʻAndrographis paniculataunuhiUa hoʻokuʻu ʻia nā capsules (200mg i kēlā me kēia lā) ma nā mākeke ʻEulopa a me ʻAmelika no ka hoʻoponopono ʻana i ka pale ʻana a me ka pale ʻana i ke anu.
Nā huahana mālama ʻili: Hoʻohui i nā ʻano anti-inflammatory a me nā sunscreens e hōʻoluʻolu i ka pōʻino UV a me ka ʻulaʻula o ka ʻili koʻikoʻi.
4. Nā Hana Hou i nā Māla e Kū mai ana
Nā lāʻau anti-angiogenic: ʻO ka hoʻomohala ʻana o nā hoʻomākaukau i kuhikuhi ʻia no nā ʻōpū a me ka retinopathy diabetic ua lilo ia i kuhikuhi koʻikoʻi o ka biology synthetic.
Mālama ola holoholona: Ua hoʻokuʻu ʻia nā mea hoʻohui anti-inflammatory a me immunomodulatory no nā ʻīlio a me nā pōpoki ma ka mākeke ʻAmelika ʻĀkau, me ka piʻi ʻana o ka ulu makahiki he 35%.
No ka ʻike hou aku, e ʻoluʻolu e hoʻokaʻaʻike mai:
Inoa: Nora
Kelepona/whatsapp: +86 15594821525
Email:nora@lfherb.com
Ka manawa hoʻouna: ʻOkakopa-20-2026