Kodi ndi chiyaniAndrographis Paniculata Extract ?
Andrographis paniculata, yomwe imadziwikanso kuti "chimwemwe cha nthawi imodzi" ndi "udzu wowawa", ndi chomera cha pachaka cha banja la Acanthaceae. Chimachokera ku South Asia monga India ndi Sri Lanka, ndipo tsopano chikufalikira kwambiri m'madera otentha komanso ozizira monga Guangdong ndi Fujian ku China. Chomera chonsecho chimakhala chowawa kwambiri, chokhala ndi tsinde lalikulu, masamba moyang'anizana, komanso nthawi yophukira maluwa kuyambira Ogasiti mpaka Seputembala. Mankhwala achikhalidwe aku China amagwiritsa ntchito zotsatira zake pochotsa kutentha ndi kuchotsa poizoni, kuziziritsa magazi ndikuchepetsa kutupa pochiza chimfine, malungo, kamwazi, zilonda ndi kulumidwa ndi njoka. Makampani amakono amatulutsa zosakaniza zogwira ntchito kuchokera ku tsinde ndi masamba kudzera mu supercritical CO₂ extraction ndi bio-enzyme hydrolysis technology kuti apange ufa wokhazikika wokhala ndi andrographolide ya 8%-98%, ndikulimbikitsa kukweza kwake kuchokera ku mankhwala azitsamba achikhalidwe kupita ku zinthu zopangira zapadziko lonse lapansi.
Zosakaniza zazikulu zogwira ntchito zaAndrographis Paniculata Ezidutswandi mankhwala a diterpenoid lactone, omwe amapanga 2%-5%24, makamaka kuphatikiza:
1. Andrographolide:Fomula ya molekyulu C₂₀H₃₀O₅, yomwe ndi 30%-50%, ndiye chinthu chachikulu chomwe chimagwira ntchito pochiza mabakiteriya komanso kutupa.
2. Dehydroandrogenographolide:Fomula ya molekyulu C₂₀H₂₈O₄, malo osungunuka 204℃, yokhala ndi ntchito yayikulu yolimbana ndi chotupa.
3. 14-Deoxyandrographolide:Fomula ya molekyulu C₂₀H₃₀O₄, yothandiza kwambiri polimbana ndi leptospirosis.
4. Neoandrographolide:Fomula ya molekyulu C₂₆H₄₀O₈, madzi abwino osungunuka, oyenera kuperekedwa pakamwa.
Kuphatikiza apo, ma flavonoid, ma phenolic acid ndi zigawo zamafuta osasunthika zimathandizira ntchito zotsutsana ndi ma antioxidants komanso zoteteza thupi ku matenda.
Kodi Ubwino Wake Ndi Chiyani?Andrographis Paniculata Extract ?
1. Kuwongolera Chitetezo cha Mthupi ndi Kuletsa Matenda
Mankhwala oletsa mabakiteriya komanso mavairasi: Andrographolide ili ndi chiwopsezo choposa 90% pa Staphylococcus aureus ndi Shigella dysenteriae, ndipo mphamvu yake pochiza matenda a m'mimba a bacillary ndi yofanana ndi chloramphenicol. Madzi ake otengedwa amatha kuchepetsa kuchuluka kwa chimfine ndi 30% ndikufupikitsa nthawi ya chimfine ndi 50%.
Kulimbitsa Chitetezo cha Mthupi: Mwa kuyambitsa ma macrophages ndi ma T lymphocytes, zimatha kuwonjezera kuchuluka kwa ma CD4⁺ lymphocytes mwa odwala omwe ali ndi kachilombo ka HIV (deta yachipatala: 405→501/mm³, p=0.002).
2. Kuletsa Kutupa ndi Angiogenesis
Mankhwala oletsa khansa mwachindunji: Dehydroandrographolide imatha kuletsa kukula kwa zotupa za W256 zomwe zaikidwa m'thupi ndikuletsa kuchulukana kwa maselo a khansa motengera mlingo.
Kuletsa angiogenesis: Andrographolide imaletsa angiogenesis ya chotupa mwa kuchepetsa kufalikira kwa VEGFR2 ndikuletsa njira yolumikizirana ya ERK/p38, ndi IC₅₀ ya 100-200μM.
3. Kagayidwe kachakudya ndi Chitetezo cha Ziwalo
Kuteteza chiwindi ndi kuchepetsa mafuta m'thupi: Andrographolide imasunga milingo ya glutathione ndipo imachepetsa malondialdehyde (MDA) mu chitsanzo cha kuwonongeka kwa chiwindi cha carbon tetrachloride ndi 40%, zomwe ndi zabwino kuposa silymarin.
Chitetezo cha mtima: Chimawongolera bwino nitric oxide/endothelin, chimachedwetsa atherosclerosis, komanso chimachepetsa kuchuluka kwa mafuta m'magazi mwa akalulu oyeserera.
4. Wotsutsa kutupa ndi wotsutsa oxidative
Madzi ochokera ku tsinde ali ndi mphamvu yamphamvu kwambiri yochotsa ma free radicals (IC₅₀=4.42μg/mL), omwe ndi amphamvu kwambiri kuwirikiza kanayi kuposa ma antioxidants opangidwa ndipo ndi oyenera matenda otupa osatha.
Kodi Ntchito Zake Ndi Ziti?Andrographis Paniculata Extract ?
1. Mankhwala ndi Chithandizo cha Zachipatala
Mankhwala oletsa matenda opatsirana: amagwiritsidwa ntchito pochiza matenda a m'mimba oyambitsidwa ndi bakiteriya, jakisoni wa chibayo ndi mankhwala opangidwa pakamwa a pharyngitis, omwe amachiritsidwa ndi chiŵerengero choposa 85%.
Mankhwala oletsa khansa: Andrographolide derivative "Andrographine" yalowa mu mayeso azachipatala a Gawo Lachiwiri a khansa ya m'magazi ndi zotupa zolimba.
Kusamalira matenda osatha: chithandizo chowonjezera cha matenda a shuga a retinopathy (0.5-2mg/kg/tsiku) ndi nyamakazi ya m'mafupa (1-3mg/kg/tsiku).
2. Ulimi wa Ziweto ndi Kubereketsa Zobiriwira
Mankhwala ena opha tizilombo: Zowonjezera zakudya za Andrographis paniculata zimachepetsa kuchuluka kwa matenda otsegula m'mimba mwa ana a nkhumba ndikuwonjezera kuchuluka kwa kupulumuka kwa nkhuku; kuwonjezera 4% ya chotsitsa ku chakudya cha carp, kuchuluka kwa kulemera kumafika 155.1%, ndipo kuchuluka kwa chakudya kumasinthidwa kufika pa 1.11.
Kupewa ndi kuletsa matenda: Jakisoni wa Andrographis paniculata umathandiza chibayo cha nkhumba ndi matenda a m'mimba, ndipo umachiritsa ndi 90% ndipo umapha ndi 10%.
3. Chakudya Chathanzi ndi Mankhwala Atsiku ndi Tsiku
Chakudya chogwira ntchito:Andrographis paniculatachotsitsaMakapisozi (200mg patsiku) amatulutsidwa m'misika ya ku Ulaya ndi ku America kuti azitha kulamulira chitetezo cha mthupi komanso kupewa chimfine.
Zosamalira khungu: Onjezani ku zinthu zotsutsana ndi kutupa ndi zoteteza ku dzuwa kuti muchepetse kuwonongeka kwa UV ndi kufiira kwa khungu lofewa.
4. Kupambana M'minda Yotukuka
Mankhwala oletsa angiogenic: Kupanga mankhwala ochizira matenda a shuga ndi retinopathy kwakhala njira yofunika kwambiri yopangira zinthu.
Chisamaliro cha ziweto: Mankhwala oletsa kutupa komanso oletsa chitetezo chamthupi kwa agalu ndi amphaka ayambitsidwa pamsika waku North America, ndi kukula kwa pachaka kwa 35%.
Kuti mudziwe zambiri, chonde lemberani:
Dzina: Nora
Foni/whatsapp: +86 15594821525
Email:nora@lfherb.com
Nthawi yotumizira: Okutobala-20-2026