Yog dab tsiAndrographis Paniculata Extract ?
Andrographis paniculata, tseem hu ua "kev zoo siab ib zaug" thiab "nyom iab", yog cov nroj tsuag txhua xyoo ntawm tsev neeg Acanthaceae. Nws yog ib txwm nyob rau sab qab teb Asia xws li Is Nrias teb thiab Sri Lanka, thiab tam sim no muaj ntau qhov chaw nyob hauv thaj chaw noo thiab kub xws li Guangdong thiab Fujian hauv Suav teb. Tag nrho cov nroj tsuag saj iab heev, nrog rau lub qia plaub fab, nplooj sib txawv, thiab lub sijhawm paj ntawm lub Yim Hli-Cuaj Hlis. Cov tshuaj suav ib txwm siv nws cov txiaj ntsig ntawm kev tshem tawm cua sov thiab tshem tawm cov tshuaj lom, txias cov ntshav thiab txo qhov o los kho mob khaub thuas, kub taub hau, mob plab, mob qhov txhab thiab nab tom. Kev lag luam niaj hnub no rho tawm cov khoom xyaw nquag los ntawm cov qia thiab nplooj los ntawm kev rho tawm CO₂ supercritical thiab bio-enzymatic hydrolysis technology los ua cov hmoov txheem nrog cov ntsiab lus andrographolide ntawm 8% -98%, txhawb nqa nws txoj kev hloov kho los ntawm cov tshuaj ntsuab hauv zos mus rau cov khoom siv raw thoob ntiaj teb.
Cov khoom xyaw tseem ceeb ntawmAndrographis Paniculata Ecov tshuaj rho tawmyog cov tshuaj diterpenoid lactone, suav txog 2% -5% 24, feem ntau suav nrog:
1. Andrographolide:Cov mis molecular C₂₀H₃₀O₅, suav txog 30% -50%, yog cov khoom tseem ceeb rau kev tua kab mob thiab tiv thaiv kev o.
2. Dehydroandrographolide:Cov mis molecular C₂₀H₂₈O₄, melting point 204 ℃, nrog rau kev ua haujlwm tiv thaiv kab mob qog nqaij hlav.
3. 14-Deoxyandrographolide:cov mis molecular C₂₀H₃₀O₄, nrog rau kev ua haujlwm zoo tshaj plaws tiv thaiv leptospirosis.
4. Neoandrographolide:Cov mis molecular C₂₆H₄₀O₈, solubility zoo hauv dej, tsim nyog rau kev npaj hauv qhov ncauj.
Tsis tas li ntawd, flavonoids, phenolic acids thiab volatile oil Cheebtsam synergistically txhim kho antioxidant thiab immunomodulatory functions.
Cov txiaj ntsig ntawm yog dab tsiAndrographis Paniculata Extract ?
1. Kev Tiv Thaiv Kab Mob Thiab Kev Tiv Thaiv Kab Mob
Tshuaj tua kab mob thiab tshuaj tua kab mob: Andrographolide muaj tus nqi tiv thaiv ntau dua 90% ntawm Staphylococcus aureus thiab Shigella dysenteriae, thiab nws cov txiaj ntsig zoo hauv kev kho mob bacillary dysentery zoo ib yam li chloramphenicol. Nws cov dej rho tawm tuaj yeem txo qhov tshwm sim ntawm tus kab mob khaub thuas los ntawm 30% thiab luv luv qhov mob khaub thuas los ntawm 50%.
Kev txhim kho kev tiv thaiv kab mob: Los ntawm kev ua kom cov macrophages thiab T lymphocytes ua haujlwm, nws tuaj yeem ua rau cov CD4⁺ lymphocytes ntau ntxiv rau cov neeg mob HIV (cov ntaub ntawv kho mob: 405 → 501 / mm³, p = 0.002).
2. Kev Tiv Thaiv Kab Mob Thiab Angiogenesis Inhibition
Kev tiv thaiv kab mob qog nqaij hlav ncaj qha: Dehydroandrographolide tuaj yeem tiv thaiv kev loj hlob ntawm W256 cov qog nqaij hlav hloov pauv thiab tiv thaiv kev loj hlob ntawm cov qog nqaij hlav qog nqaij hlav hauv txoj kev uas nyob ntawm seb muaj pes tsawg koob tshuaj.
Tiv Thaiv Kab Mob Angiogenesis: Andrographolide thaiv kab mob qog nqaij hlav angiogenesis los ntawm kev txo qis VEGFR2 kev qhia tawm thiab tiv thaiv ERK / p38 signaling pathway, nrog IC₅₀ ntawm 100-200μM.
3. Kev Ua Haujlwm Metabolism Thiab Kev Tiv Thaiv Kab Mob
Kev tiv thaiv daim siab thiab txo cov roj lipid: Andrographolide tswj cov qib glutathione thiab txo cov malondialdehyde (MDA) hauv cov qauv raug mob ntawm daim siab carbon tetrachloride los ntawm 40%, uas zoo dua li silymarin.
Kev tiv thaiv kab mob plawv: Tswj hwm qhov sib npaug ntawm nitric oxide/endothelin, qeeb qeeb atherosclerosis, thiab txo cov roj lipid hauv cov luav sim.
4. Tshuaj Tiv Thaiv Kab Mob Thiab Tshuaj Antioxidant
Cov dej rho tawm ntawm cov qia muaj peev xwm tshaj plaws los tshem tawm cov dawb radicals (IC₅₀ = 4.42μg / mL), uas yog 4 npaug zoo dua li cov tshuaj antioxidants hluavtaws thiab tsim nyog rau cov kab mob o.
Cov Ntawv Thov Yog Dab TsiAndrographis Paniculata Extract ?
1. Tshuaj Kho Mob Thiab Kev Kho Mob Hauv Tsev Kho Mob
Cov tshuaj tua kab mob: siv rau cov kab mob dysentery, kev txhaj tshuaj mob ntsws thiab kev npaj qhov ncauj rau mob pharyngitis, nrog rau tus nqi kho mob ntau dua 85%.
Cov tshuaj tiv thaiv kab mob qog nqaij hlav: Andrographolide derivative "Andrographine" tau nkag mus rau theem II kev sim tshuaj rau leukemia thiab cov qog nqaij hlav khov kho.
Kev tswj kab mob ntev: kev kho mob adjuvant ntawm diabetic retinopathy (0.5-2mg/kg/hnub) thiab rheumatoid arthritis (1-3mg/kg/hnub).
2. Kev Ua Liaj Ua Teb thiab Kev Yug Tsiaj Ntsuab
Lwm cov tshuaj tua kab mob: Cov tshuaj ntxiv rau Andrographis paniculata pub rau tsiaj txhu txo qhov raws plab ntawm cov menyuam npua thiab ua rau cov menyuam qaib muaj sia nyob ntau dua; ntxiv 4% extract rau cov tsiaj carp, qhov hnyav nce mus txog 155.1%, thiab qhov hloov pauv pub tau zoo rau 1.11.
Kev tiv thaiv thiab tswj kab mob: Kev txhaj tshuaj Andrographis paniculata kho cov kab mob ntsws thiab mob plab hnyuv ntawm npua, nrog rau kev kho mob ntawm 90% thiab kev tuag ntawm 10%.
3. Khoom Noj Khoom Haus thiab Cov Tshuaj Txhua Hnub
Cov khoom noj muaj txiaj ntsig:Andrographis paniculatacov tshuaj rho tawmcov tshuaj ntsiav (200mg ib hnub) tau tso tawm hauv cov khw European thiab Asmeskas rau kev tswj hwm lub cev tiv thaiv kab mob thiab tiv thaiv mob khaub thuas.
Cov khoom siv saib xyuas tawv nqaij: Ntxiv rau cov tshuaj tiv thaiv kev o thiab cov tshuaj pleev thaiv hnub kom txo qhov puas tsuaj ntawm UV thiab liab ntawm cov tawv nqaij rhiab heev.
4. Kev Tshwm Sim Tshiab Hauv Cov Thaj Chaw Tshiab
Cov tshuaj tiv thaiv angiogenic: Kev tsim cov tshuaj npaj rau cov qog thiab cov kab mob ntshav qab zib retinopathy tau dhau los ua qhov kev taw qhia tseem ceeb ntawm kev tsim cov tshuaj lom neeg.
Kev saib xyuas tsiaj: Cov tshuaj tiv thaiv kev o thiab cov tshuaj tiv thaiv kab mob rau dev thiab miv tau tsim tawm hauv kev lag luam North American, nrog rau kev loj hlob txhua xyoo ntawm 35%.
Yog xav paub ntxiv, thov hu rau:
Lub Npe: Nora
Xov tooj/whatsapp: +86 15594821525
Email:nora@lfherb.com
Lub sijhawm tshaj tawm: Lub Kaum Hli-20-2026