ChiiAndrographis Paniculata Extract ?
Andrographis paniculata, inozivikanwawo se "kamwe chete mufaro" uye "huswa hunovava", chirimwa chegore negore chemhuri yeAcanthaceae. Chinowanikwa kuSouth Asia senge India neSri Lanka, uye ikozvino chapararira munzvimbo dzine hunyoro uye dzinopisa dzakadai seGuangdong neFujian muChina. Chirimwa chose chinonaka chinovava zvikuru, chine hunde yakaenzana, mashizha akatarisana, uye nguva yemaruva kubva muna Nyamavhuvhu-Gunyana. Mishonga yechivanhu yeChinese inoshandisa mhedzisiro yayo yekubvisa kupisa uye kubvisa chepfu, kutonhora ropa uye kuderedza kuzvimba kurapa dzihwa, fivha, manyoka, maronda uye kurumwa nenyoka. Indasitiri yemazuva ano inoburitsa zvinhu zvinoshanda kubva muhunde nemashizha kuburikidza nekubvisa CO₂ zvakanyanya uye tekinoroji ye bio-enzyme hydrolysis kugadzira hupfu hwakajairwa hune andrographolide ye8%-98%, ichisimudzira kuvandudzwa kwayo kubva pamishonga yemishonga yechivanhu kuenda kuzvinhu zvepasi rose.
Zvinhu zvikuru zvinoshanda zveAndrographis Paniculata Ezvinyorwandiwo macompounds e diterpenoid lactone, anoumba 2%-5%24, anosanganisira:
1. Andrographolide:Fomura yemorekuru C₂₀H₃₀O₅, inoumba 30%-50%, ndiyo chinhu chikuru chinoshanda pakurwisa mabhakitiriya uye kudzivirira kuzvimba.
2. Dehydroandrogenolide:fomura yemolekyulu C₂₀H₂₈O₄, poindi yekunyunguduka 204℃, ine basa guru rekudzivirira bundu.
3. 14-Deoxyandrographolide:fomura yemamorekuru C₂₀H₃₀O₄, inoshanda zvakanyanya pakurwisa leptospirosis.
4. Neoandrographolide:Fomura yemolekyulu C₂₆H₄₀O₈, inonyunguduka zvakanaka mumvura, yakakodzera kugadzirwa nemuromo.
Pamusoro pezvo, maflavonoid, ma phenolic acids uye zvikamu zvemafuta zvinoshanduka-shanduka zvinowedzera simba rekuchengetedza ma antioxidants uye immune system.
Ndezvipi ZvakanakiraAndrographis Paniculata Extract ?
1. Kugadzirisa Dziviriro yeMhuka Uye Kurwisa Kutapukirwa
Inorwisa mabhakitiriya uye inorwisa mavhairasi: Andrographolide ine mwero wekudzivirira weStaphylococcus aureus neShigella dysenteriae unodarika 90%, uye kushanda kwayo mukurapa manyoka emudumbu kwakafanana nechloramphenicol. Mvura yayo inogona kuderedza kuwanda kwefuruwenza ne30% uye kupfupisa nguva yefuruwenza ne50%.
Kuvandudza Dziviriro yeMhuka: Nekushandisa macrophages neT lymphocytes, zvinogona kuwedzera huwandu hweCD4⁺ lymphocytes muvarwere vane HIV (data rekiriniki: 405→501/mm³, p=0.002).
2. Kudzivirira Kubuda Kwebundu Uye Kukonzera Kupararira Kweangiogenesis
Mushonga wekudzivirira bundu zvakananga: Dehydroandrographolide inogona kudzivirira kukura kwebundu reW256 rakaiswa panzvimbo imwe uye kudzivirira kuwanda kwemasero ekenza zvichienderana nedosi.
Kurwisa angiogenesis: Andrographolide inovhara angiogenesis yebundu nekuderedza kutaurwa kweVEGFR2 uye kudzivirira nzira yekutumira masaini yeERK/p38, neIC₅₀ ye100-200μM.
3. Kugadzirwa kweMetabolism uye Kudzivirirwa kweZviri Muviri
Kudzivirira chiropa uye kuderedza mafuta mumuviri: Andrographolide inochengetedza huwandu hweglutathione uye inoderedza malondialdehyde (MDA) mu carbon tetrachloride liver injury model ne40%, izvo zviri nani pane silymarin.
Kudzivirira mwoyo netsinga dzeropa: Kunodzora kuenzana kwe nitric oxide/endothelin, kunononotsa atherosclerosis, uye kunoderedza huwandu hwemafuta muropa mutsuro dzinoedzwa.
4. Inodzivirira kuzvimba uye inorwisa okisijeni
Mvura inotorwa kubva mudzinde ine simba rakasimba rekubvisa ma free radicals (IC₅₀=4.42μg/mL), iyo inoshanda zvakapetwa ka4 kupfuura ma antioxidants ekugadzira uye yakakodzera zvirwere zvisingaperi zvekuzvimba.
Ndezvipi ZvinoshandiswaAndrographis Paniculata Extract ?
1. Mishonga Nekurapwa Kwekiriniki
Mishonga yekudzivirira hutachiona: inoshandiswa pakurwisa manyoka ebhakitiriya, jekiseni remabayo uye mishonga yemuromo ye pharyngitis, ine mwero wekurapwa kwechirwere ichi unopfuura 85%.
Mishonga inorwisa bundu: Andrographolide derivative "Andrographine" yapinda mumiedzo yekiriniki yePhase II ye leukemia ne bundu rakasimba.
Kurapa zvirwere zvisingaperi: kurapa kwakawedzerwa kwechirwere cheshuga chinonzi retinopathy (0.5-2mg/kg/zuva) uye rheumatoid arthritis (1-3mg/kg/zuva).
2. Kuchengeta Zvipfuyo Uye Kuberekesa Zvisina Kusvibira
Mishonga inorwisa mabhakitiriya: Mishonga inowedzerwa paniculata inosanganisa Andrographis paniculata inoderedza huwandu hwemanyoka enguruve uye inowedzera huwandu hwehupenyu hwehuku dzehuku; kuwedzera 4% yezvakatorwa muchikafu che carp, huwandu hwehuremu hunosvika 155.1%, uye huwandu hwekuchinja kwechikafu hunogadziriswa kusvika 1.11.
Kudzivirira nekudzivirira zvirwere: Jekiseni reAndrographis paniculata rinorapa pneumonia yenguruve ne enteritis, nechiyero chekurapa che90% uye chiyero cherufu che10%.
3. Zvekudya Zvehutano Nemakemikari Ezuva Nezuva
Chikafu chinoshanda:Andrographis paniculatachidimbuMakapisiyu (200mg pazuva) anotangwa mumisika yeEurope neAmerica kuti agadzirise dziviriro yemuviri uye kudzivirira dzihwa.
Zvigadzirwa zvekuchengetedza ganda: Wedzera kune zvinodzivirira kuzvimba uye mafuta ekudzivirira zuva kuti uderedze kukuvara kweUV uye kutsvuka kweganda rinonzwa kusuruvara.
4. Kubudirira Muminda Iri Kubudirira
Mishonga inorwisa angiogenic: Kugadzirwa kwemishonga yakanangana nebundu uye chirwere cheshuga retinopathy kwave kuri nzira huru yekugadzirwa kwezvinhu.
Kuchengetedza Zvipfuyo: Mishonga yekudzivirira kuzvimba uye yekudzivirira muviri yembwa nekatsi yatanga kushandiswa mumusika wekuNorth America, nekukura kwegore negore kwe35%.
Kuti uwane rumwe ruzivo, ndapota taura ne:
Zita: Nora
Nhare/whatsapp: +86 15594821525
Email:nora@lfherb.com
Nguva yekutumira: Gumiguru-20-2026