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High Purity Metformin CAS 657-24-9 Metformin Manufacturer

Short Description:

Brand Name: Newgreen
Product Specification: 99%
Shelf Life: 24months
Storage Method: Cool Dry Place
Appearance: White Powder
Application: Pharm grade

Packing: 25kg/drum


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Metformin: A powerful drug for treating diabetes

1.What is metformin? 

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Biguanides are found in goat grass (Galega Officinalis), a plant that has been used in folk medicine for hundreds of years. The pharmacological action of the plant itself is dependent on goatine (Isoamylene guanidine). Phenformin, Buformin, and metformin are all chemically synthesized and consist of two guanidine molecules. Metformin is an oral drug widely used to treat type 2 diabetes. It belongs to a class of drugs called biguanides and is considered a first-line treatment for diabetes. 

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2.How does metformin work?

Metformin's main function is to reduce the amount of sugar produced by the liver and make the body's cells more sensitive to insulin. It effectively lowers blood sugar levels and helps regulate the body's response to insulin.

Metformin regulates blood sugar mainly by inhibiting liver sugar output. Metformin mainly relies on organic cationic transporter 1(OCT 1) to enter hepatocytes, and then partially inhibits mitochondrial respiratory chain complex 1, resulting in decreased intracellular ATP and increased AMP levels. We all know that the decrease of ATP and the increase of AMP in the cell will directly inhibit gluconeogenesis and reduce the conversion of glycerol to glucose.

The increased AMP/ATP ratio caused by metformin also activates the AMPK signaling pathway, which inhibits fat synthesis and increases the body's sensitivity to insulin.

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3.What are the benefits of metformin?
Metformin provides multiple benefits to people with diabetes:
1) Blood sugar control: By reducing sugar production in the liver and improving insulin sensitivity, metformin helps regulate blood sugar levels and prevent them from going too high or too low.
2) Weight management: Metformin usually results in moderate weight loss in people with diabetes. It does this by reducing appetite, increasing feelings of fullness, and helping to tap into glucose and fat stores for energy.
3) Cardiovascular Protection: Studies show that metformin may reduce the risk of cardiovascular disease, such as heart disease and stroke, in people with diabetes.
4) Polycystic ovary syndrome (PCOS): In addition to treating diabetes, metformin is used to treat PCOS, a hormone disorder that affects women. It helps regulate the menstrual cycle, reduces insulin resistance, and aids in fertility.
 
4.Where can metformin be used?
Metformin is mainly used to treat type 2 diabetes. It may be used alone or in combination with other oral antidiabetic medications or in combination with insulin therapy, depending on individual needs. Metformin is indicated for use in newly diagnosed individuals and in individuals who have long-term control of diabetes. In summary, metformin is a powerful drug widely used to treat type 2 diabetes and PCOS. It has benefits such as blood sugar control, weight management, cardiovascular protection, and PCOS symptom relief. Due to its effectiveness and widespread use, metformin has become an important tool in helping individuals live healthier lives while effectively managing their condition.

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company profile

Newgreen is a leading enterprise in the field of food additives, established in 1996, with 23 years of export experience. With its first-class production technology and independent production workshop, the company has helped the economic development of many countries. Today, Newgreen is proud to present its latest innovation - a new range of food additives that utilize high technology to improve food quality.

At Newgreen, innovation is the driving force behind everything we do. Our team of experts is constantly working on the development of new and improved products to improve food quality while maintaining safety and health. We believe that innovation can help us overcome the challenges of today's fast-paced world and improve the quality of life for people around the globe. The new range of additives is guaranteed to meet the highest international standards, giving customers peace of mind.We strive to build a sustainable and profitable business that not only brings prosperity to our employees and shareholders, but also contributes to a better world for all.

Newgreen is proud to present its latest high-tech innovation - a new line of food additives that will improve the quality of food worldwide. The company has long been committed to innovation, integrity, win-win, and serving human health, and is a trustworthy partner in the food industry. Looking to the future, we are excited about the possibilities inherent in technology and believe that our dedicated team of experts will continue to provide our customers with cutting-edge products and services.

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OEM service

We supply OEM service for clients.
We offer customizable packaging, customizable products, with your formula, stick labels with your own logo! Welcome to contact us!


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