● What Is Ashwagandha Extract ?
Among the mysterious herbs in Indian Ayurvedic medicine that have been passed down for 4,000 years, Withania somnifera stands out for its unique adaptogenic properties. This plant, known as “Indian ginseng”, has been deeply developed through modern biotechnology in recent years, and its root extract has set off a boom in the global health industry. The latest research data in 2025 shows that the market size of Withania somnifera extract has exceeded US$1.2 billion, with an annual growth rate of 15%, becoming a star ingredient in the fields of anti-fatigue and cognitive enhancement.
Ashwagandha is mainly distributed in arid areas of India and Africa. Its roots are rich in active ingredients and are often taken with milk and honey in traditional Ayurvedic medicine.
Ashwagandha extract uses ethanol-water mixed solvent and a multi-stage countercurrent extraction process to prepare extracts of different proportions, and can also prepare standard monomer withanolides
Ashwagandha extract contains more than 200 compounds, and the core active ingredients include:
Withanolides (accounting for 1.5%-35%): such as Withaferin A and Withanolide D, which have anti-inflammatory and neuroprotective effects.
Alkaloids: such as Withanine, which regulate GABA receptor activity and relieve anxiety.
Sterols: β-sitosterol synergistically enhances immune regulation.
Phenolic substances: The ability to scavenge free radicals reaches DPPH IC50=34.4 μg/mL, which is better than vitamin C.
● What Are The Benefits Of Ashwagandha Extract ?
Based on more than 120 clinical trials and molecular mechanism studies, Ashwagandha extract shows multi-dimensional health value:
1. Neuroenhancement
Cognitive improvement: 600 mg daily for 8 consecutive weeks, episodic memory improved by 14.77%, working memory improved by 9.26% (COMPASS score).
Brain fog removal: Improve the information processing speed of MCI (mild cognitive impairment) patients by regulating the BDNF pathway.
2. Stress Management
Cortisol regulation: Ashwagandha extract reduce stress hormone levels by 32% and activate the negative feedback mechanism of the HPA axis.
Mood improvement: The POMS scale shows a 41% decrease in anxiety and depression scores, and synergistically enhances SSRI drugs.
3. Metabolic Regulation
Glycemic control: Inhibits SGLT2 (IC50=9.6 kcal/mol) and α-glucosidase, reducing postprandial blood sugar peaks by 37%.
Testosterone enhancement: Serum testosterone levels in male subjects increased by 14.5%, improving reproductive function.
4. Immunity And Anti-Aging
Antioxidant defense: Increases SOD activity by 2.3 times and reduces IL-6 inflammatory factors by 42%.
Telomere protection: Epigenetic studies show that it can slow down the rate of telomere shortening
● What Are The Application Of Ashwagandha Extract ?
1. Dietary supplements
Capsules/tablets: Daily dose 250-600mg, “Brain Gas Station” series products launched for working people.
Sports nutrition: Compounded with L-carnitine, it improves endurance by 27% and reduces muscle breakdown.
2. Functional food
Sleep-aid beverages: Add 5% ashwagandha extract and valerian root to shorten the time to fall asleep by 58%.
Energy bars: Synergize ashwagandha extract with maca and guarana, continuous energy supply for 6 hours.
3. Pharmaceutical preparations
Adjuvant treatment of diabetes: Combined with metformin, HbA1c is reduced by 0.8%, reducing the risk of hypoglycemia.
Neurodegenerative diseases: Alzheimer’s disease model shows that Aβ amyloid protein deposition is reduced by 39%.
4. Cosmetic raw materials
Anti-aging essence: 0.1% ashwagandha extract inhibits MMP-1 activity by 63%, reducing photoaging wrinkles.
Sensitive skin repair: Regulates TRPV1 channel, soothing redness better than bisabolol
● Newgreen Supply High Quality Ashwagandha Extract Powder
Post time: Jul-22-2025
