• YiniI-Streptococcus Thermophilus ?
Emlandweni omude wokufuywa kwabantu ngama-microorganisms, i-Streptococcus thermophilus isibe uhlobo lwegumbi lemboni yobisi olunokumelana nokushisa okuyingqayizivele kanye namandla okusebenza kwe-metabolic. Ngo-2025, imiphumela yakamuva yocwaningo ye-Chinese Academy of Food Fermentation Industries kanye ne-International Dairy Federation (IDF) yaqinisekisa isimo sayo sezinhlobo ezizimele ezingeni le-genome okokuqala ngqa, okumaka isigaba esisha ekuqondeni kwesayensi yaleli “golide eliwuketshezi”. Njengomumo wemikhiqizo yobisi evutshiwe ekhiqiza amathani angaphezu kwezigidi ezingama-30 ngonyaka emhlabeni wonke, iStreptococcus thermophilus yeqa imingcele yendabuko futhi isungula igagasi lokuqamba okusha ekudleni okusebenzayo, ezempilo kanye neminye imikhakha.
I-Streptococcus thermophilus yaqanjwa okokuqala ngu-Orla-Jensen ngo-1919. Ngemva kwengxabano yokwehliswa kwezinhlobo zezinhlobo ezingaphansi ngo-1984 nokubuyiselwa kwezinhlobo zezilwane ngo-1991, yagcina isisungule isimo sayo sezinhlobo ezizimele ngokusebenzisa ukulandelana kwe-genome (ANI ≥ 96.5%, dD070 ≥ I-Union yase-China, dD075) I-FDA kanye ne-IDF bonke bakufake ohlwini njengohlobo lokudla oluphephile (GRAS). Ngo-2025, uhlelo lwesihlanu lwe-IDF “Uhlu Lwamagciwane Okudla Okuvundile” luzoqedela ukubuyekezwa okujwayelekile.
I-Streptococcus thermophilus i-Gram-positive, non-spore-forming, i-facultative anaerobic, enezinga lokushisa eliphezulu lokukhula elingu-45-50°C, ibanga lokubekezelela i-pH lika-3.5-8.5, nokumelana nokushisa okuqinile (izinga lokusinda> 80% ngemva kokwelashwa okungu-85°C imizuzu engu-30).
• Yiziphi Izinzuzo ZazoI-Streptococcus Thermophilus?
Ngokusekelwe ezifundweni ezingaphezu kuka-2,000 emhlabeni wonke, i-Streptococcus thermophilus ibonisa inani lezempilo le-multi-dimensional:
1. Ukuphathwa Kwempilo Yamathumbu
Ukulawulwa kwezitshalo zebhaktheriya: Vimbela amagciwane e-pathogenic ngokukhipha ama-bacteriocins (afana ne-Salivaricin), ukwandisa ukuchichima kwe-bifidobacteria yamathumbu izikhathi ezingu-2-3.
Ukulungiswa kwe-mucosal: Phakamisa ukuvezwa kofuzo lwe-Gal3ST2, unciphise i-fucosylation ye-colonic mucin, futhi ukhulule ukuvuvukala kwe-mucosal yamathumbu okwenziwa ngamakhemikhali.
2. Ukulawulwa kweMetabolic
Ukulawula ushukela wegazi: Ukungenelela kwamagciwane okubulala ukushisa kunganciphisa ushukela wegazi ozila ukudla kumagundane anesifo sikashukela ngo-23% futhi kuthuthukise ukuzwela kwe-insulin (inkomba ye-HOMA-IR yehle ngo-41%).
I-cholesterol metabolism:I-Streptococcus thermophilusvimbela umsebenzi we-HMG-CoA reductase, wehlise i-serum LDL-C ngo-8.4%, futhi ukhuphule amazinga e-HDL-C.
3. Ukuthuthukiswa Kokuzivikela komzimba
Umthetho we-Cytokine: Khuthaza ukukhishwa kwe-IL-10 (ukugxila kukhuphuke izikhathi ze-1.8), vimbela i-TNF-α (yehle ngo-52%), futhi ukhulule ukuvuvukala okungapheli.
Ukuqiniswa kwesithiyo se-mucosal: Kuthuthukisa ukubonakaliswa kwamaprotheni ahlangene (ZO-1, Occludin) futhi kunciphisa ukuvuthwa kwamathumbu (i-FITC-dextran permeability yehle ngo-37%).
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4. Amandla Okumelana Nomdlavuza
Ukuvinjelwa komdlavuza we-Colorectal: Kwehlisa izinga le-carcinogens ngendlela ye-β-galactosidase, kunciphisa ukwenzeka kwesimila kumagundane e-Apcmin/+ ngo-58%.
I-Apoptosis induction: Yenza kusebenze indlela ye-Caspase-3, ibangele ukwanda okuphindwe ka-4.3 kwezinga le-apoptosis lamaseli omdlavuza we-colon we-HT-29.
• Yini Isicelo SeI-Streptococcus Thermophilus?
I-Streptococcus thermophilus yeqa imingcele yendabuko futhi yakha i-matrix yohlelo lokusebenza ehlukahlukene:
1. Imboni yobisi
Iyogathi/ushizi: ihlanganiswe ne-Lactobacillus bulgaricus, ifinyeza isikhathi sokuhlangana sibe amahora angu-4 futhi ikhulise isivuno somkhiqizo ngo-15%.
Imikhiqizo ephansi kashukela/amafutha aphansi: Ngobuchwepheshe be-EPS synthesis, ubulukhuni bukashizi onamafutha aphansi bukhuphuka izikhathi ezingu-2 ukuze kulingise ukuthungwa kwamafutha agcwele.
2. Ukudla Okusebenzayo
Ukudla okulawulwa ngoshukela: okusanhlamvu kwasekuseni okunempushana yebhaktheriya engu-5% kungabambezela ukukhuphuka koshukela wegazi kwangemva kokudla ngamahora angu-1.5.
I-Immunoenhancer:I-Streptococcus thermophiluskuhlanganiswe ne-oligofructose, izinga lokutheleleka ngomgudu wokuphefumula ezinganeni lehle ngo-33%.
3. Impilo Yezempilo
Ukudla okukhethekile kwezokwelapha: okusetshenziselwa amalungiselelo okunomsoco we-enteral ukuze kuthuthukiswe isimo sokudla okunempilo kweziguli ze-chemotherapy (i-albumin inyuke ngo-1.2 g/dL).
Imithi ye-Probiotic: ihlanganiswe ne-bifidobacteria ukuze kuthuthukiswe amaphilisi okwelapha e-IBS, anesilinganiso sokukhululeka sokuqunjelwa esingu-78%.
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4. Ezolimo kanye nokuvikelwa kwemvelo.
Izithako zokudla: Yehlisa izinga lohudo lwengulube ngo-42% futhi ukhuphule izinga lokuguqula ukudla ngo-11%.
Ukulungiswa kwamanzi angcolile: Yehlisa izinga le-COD yamanzi angcolile obisi ngo-65% futhi wehlise ukukhiqizwa kodaka ngama-30%.
• Newgreen Supply High QualityI-Streptococcus ThermophilusImpushana
Isikhathi sokuthumela: Jul-28-2025
