I-Ashwagandha Extract: Ukuqopha Ukusetshenziswa kwe- "Indian Ginseng"

●Yini? I-Ashwagandha Extract?

Phakathi kwamakhambi angaqondakali emithini ye-Indian Ayurvedic esedluliselwe phansi iminyaka eyi-4,000, i-Withania somnifera igqama ngezakhiwo zayo ezihlukile ze-adapogenic. Lesi sitshalo, esaziwa ngokuthi “i-ginseng yaseNdiya”, senziwe sathuthukiswa ngokujulile nge-biotechnology yesimanje eminyakeni yamuva, futhi ukukhishwa kwezimpande zaso kudale ukuchuma embonini yezempilo yomhlaba wonke. Idatha yakamuva yocwaningo ngo-2025 ibonisa ukuthi usayizi wemakethe we-Withania somnifera ekhishwe udlule i-US$1.2 billion, ngezinga lokukhula lonyaka lika-15%, libe isithako senkanyezi emikhakheni yokulwa nokukhathala kanye nokuthuthukiswa kwengqondo.

I-Ashwagandha isatshalaliswa kakhulu ezindaweni ezomile zaseNdiya nase-Afrika. Izimpande zayo zicebile izithako ezisebenzayo futhi zivame ukuthathwa ngobisi noju emithini yendabuko ye-Ayurvedic.

Ukukhishwa kwe-Ashwagandhaisebenzisa i-ethanol-water mix solvent kanye ne-multi-stage countercurrent extraction process ukuze ilungise izingcaphuno zezilinganiso ezihlukene, futhi ingalungisa i-monomer evamile nama-anolides.

Ukukhishwa kwe-Ashwagandhaiqukethe izinhlanganisela ezingaphezu kuka-200, futhi izithako ezisebenzayo eziyinhloko zihlanganisa:

I-Withanolides (ibalwa ku-1.5% -35%): njenge-Witaferin A kanye ne-Withanolide D, enemiphumela elwa nokuvuvukala kanye ne-neuroprotective.

Ama-alkaloid: afana ne-Witanine, alawula umsebenzi we-GABA receptor futhi akhulule ukukhathazeka.

I-Sterols: I-β-sitosterol ithuthukisa ngokuhambisana nokulawulwa kwamasosha omzimba.

I-Phenolic substances: Amandla okukhipha ama-radicals mahhala afinyelela ku-DPPH IC50=34.4 μg/mL, engcono kune-vitamin C..

● Ziyini IIzinzuzoKweI-Ashwagandha Extract ?

Ngokusekelwe ezivivinyweni ezingaphezu kwe-120 zemitholampilo kanye nezifundo ze-molecular mechanism,Ukukhishwa kwe-Ashwagandhaibonisa inani lezempilo le-multi-dimensional:

1. I-Neuroenhancement

Ukuthuthukiswa kwengqondo: 600 mg nsuku zonke amasonto angu-8 alandelanayo, inkumbulo ye-episodic yaba ngcono ngo-14.77%, inkumbulo yokusebenza yaba ngcono ngo-9.26% (amaphuzu e-COMPASS).

Ukususwa kwenkungu yobuchopho: Thuthukisa isivinini sokucutshungulwa kolwazi leziguli ze-MCI (ukukhubazeka kwengqondo okumaphakathi) ngokulawula indlela ye-BDNF.

2. Ukulawula Ukucindezeleka

I-Cortisol Regulation:Ukukhishwa kwe-Ashwagandha rehlisa amazinga e-hormone yokucindezeleka ngo-32% futhi enze kusebenze indlela yempendulo engemihle ye-axis ye-HPA.

Ukuthuthukiswa kwemizwa: Isikali se-POMS sibonisa ukwehla okungama-41% kuzikolo zokukhathazeka nokucindezeleka, futhi sithuthukisa izidakamizwa ze-SSRI ngokubambisana.

3. Ukulawulwa kweMetabolic

Ukulawulwa kwe-Glycemic: Kuvimbela i-SGLT2 (IC50=9.6 kcal/mol) kanye ne-α-glucosidase, kwehlisa izinga likashukela wegazi ngemva kokudla ngama-37%.

Ukuthuthukiswa kwe-testosterone: Amazinga e-serum testosterone ezifundweni zabesilisa akhuphuke ngo-14.5%, athuthukisa umsebenzi wokuzala.

4. Ukungavikeleki Nokuguga

Ukuzivikela kwe-Antioxidant: Kwenyusa umsebenzi we-SOD ngezikhathi ze-2.3 futhi kunciphisa izici ezivuthayo ze-IL-6 ngama-42%.

Ukuvikelwa kwe-telomere: Ucwaningo lwe-Epigenetic lubonisa ukuthi linganciphisa izinga lokufinyezwa kwe-telomere

● Ziyini IIsiceloOf I-Ashwagandha Extract?

1. Izithako zokudla

Amaphilisi/amaphilisi: Umthamo wansuku zonke we-250-600mg, imikhiqizo yochungechunge lwe-"Brain Gas Station" eyethulwe abantu abasebenzayo.

Ukudla okunomsoco wezemidlalo: Kuhlanganiswe ne-L-carnitine, kuthuthukisa ukukhuthazela ngo-27% futhi kunciphisa ukuwohloka kwemisipha.

2. Ukudla okusebenzayo

Iziphuzo zokusiza ukulala: Engeza u-5%i-ashwagandha extractkanye nempande ye-valerian ukunciphisa isikhathi sokulala ngo-58%.

Amabha Amandla: Hlanganisa aukukhishwa kwe-shwagandhange-maca ne-guarana, ukunikezwa kwamandla okuqhubekayo amahora angu-6.

3. Amalungiselelo ekhemisi

Ukwelashwa kwe-Adjuvant yesifo sikashukela: Ihlanganiswe ne-metformin, i-HbA1c yehla ngo-0.8%, kunciphisa ubungozi be-hypoglycemia.

Izifo ze-Neurodeergenerative: Imodeli yesifo i-Alzheimer's ikhombisa ukuthi i-Aβ amyloid protein deposition yehliswa ngama-39%.

4. Izinto zokusetshenziswa zezimonyo

I-Essence Anti-ukuguga: 0.1%i-ashwagandha extractivimbela umsebenzi we-MMP-1 ngo-63%, inciphisa imibimbi yokuthwebula izithombe.

Ukulungiswa kwesikhumba okuzwelayo: Ilawula isiteshi se-TRPV1, ububomvu obupholile kangcono kune-bisabolol

● Newgreen Supply High Quality I-Ashwagandha Extract Impushana