●Ke Eng? Gymnema Sylvestre Extract?
Gymnema sylvestre ke sefate sa morara sa lelapa la Apocynaceae, se ajwang haholo dibakeng tsa tropike tse kang Guangxi le Yunnan naheng ya China. Tšebeliso ea meriana ea setso e tsepamisitsoe haholo makhasing a eona, a sebelisetsoang ho theola tsoekere e maling, ho thibela ho bola ha meno le ho thibela maikutlo a tatso e monate. Leha ho le joalo, liphuputso tsa morao-rao li fumane hore mehloli ea eona ea kutu e boetse e na le metsoako e mengata e sebetsang, 'me mehloli e mengata ea makhasi a feta ka makhetlo a 10. Ka mokhoa o hlophisitsoeng oa karohano ea solvent, n-butanol le 95% likarolo tsa ethanol tsa li-extracts tsa stem li bontšitse litšobotsi tse tšoanang tsa UV le likarolo tse tšesaane tsa chromatography ho makhasi, e leng se bontšang hore metsoako e sebetsang ea bobeli e lumellana haholo. Tšibollo ena e fana ka tšehetso ea bohlokoa bakeng sa ho atolosa mehloli ea lithethefatsi le ho fokotsa litšenyehelo tsa ntlafatso.
Motsoako oa lik'hemik'hale oaGymnema sylvestre ntshae rarahane ebile e fapane, haholoholo ho kenyelletsa:
Cyclols le li-steroids:Conduritol A, e le karolo ea mantlha ea hypoglycemic, e ka khothaletsa motsoako oa glycogen; stigmasterol le glucoside ea eona e na le litlamorao tse khahlanong le ho ruruha;
Saponin metsoako:Ka 2020, li-saponins tse ncha tse robeli tsa C21 steroidal (gymsylvestrosides AH) li ile tsa aroloa ka lekhetlo la pele, 'me mehaho ea tsona e na le glucuronic acid le rhamnose units, e leng se fanang ka ts'ebetso e ikhethang ea likokoana-hloko;
Likarolo tsa Synergistic:li-alkanol tsa ketane e telele joalo ka lupine cinnamyl ester le n-heptadecanol li ntlafatsa bokhoni ba antioxidant ka ho hlakola li-radicals tsa mahala.
Ke habohlokoa ho hlokomela hore bohloeki ba stem saponins bo ka fihla ho feta 90%, 'me tlhoekiso e kholo e ka finyelloa ka theknoloji ea ethanol recrystallization, ho qoba tšebeliso ea li-solvents tse chefo tse kang chloroform.
●Ke Eng SeoMelemoEa Gymnema Sylvestre Extract?
1. Taolo ea lefu la tsoekere
Lithuto tsa pharmacological li bonts'itse hore "stem ethanol extract" e ka fokotsa tsoekere ea mali ka 30% -40% ho litoeba tse nang le lefu la tsoekere la alloxan, mme mokhoa oa ts'ebetso o bonts'a synergy ea litsela tse ngata:
Tšireletso ea lihlekehleke: lokisa lisele tsa β tse senyehileng le ho eketsa secretion ea insulin;
Glucose metabolism regulation: khothalletsa sebete sa glycogen synthesis le ho thibela intestinal α-glucosidase mosebetsi (le hoja sekhahla sa ho thibela monomer saponin ke 4.9% -9.5% feela, phello ea synergistic ea qotsulo eohle e bohlokoa);
Ho kenella ha khatello ea oxidative: fokotsa maemo a lipid peroxide le ho eketsa ts'ebetso ea superoxide dismutase.
2. Tšireletso ea methapo
Phuputso e phatlalalitsoeng ho Scientific Reports ka 2025 e senotse bokhoni ba hoGymnema sylvestrentshakalafong ea lefu la Alzheimer's (AD):
Ho lebisa tlhokomelo ea liprotheine tsa bohlokoa tsa AD: metabolites S-adenosylmethionine le bamipine li na le kamano e phahameng ea tlamahano le β-secretase (BACE1) le monoamine oxidase B (MAO-B), ho fokotsa ho behoa ha β-amyloid;
Melao ea tsamaiso ea methapo ea methapo: ka ho kenya ts'ebetso ea cAMP / PI3K-Akt ea pontšo, ho eketsa polelo ea choline acetyltransferase (Chat), ha ho ntse ho fokotsa mosebetsi oa acetylcholinesterase, le ho ntlafatsa phetisetso ea synaptic;
Netefatso ea liteko tsa lisele: Ka mokhoa oa Aβ42-induced neural cell model, qotsulo e fokolitse tlhahiso ea mefuta ea reactive oxygen (ROS) ka 40% le sekhahla sa apoptosis ka ho feta 50%.
● Ke Eng SeoKopoOf Gymnema Sylvestre Extract ?
Tsoelo-pele ea meriana: Khampani ea Guangxi Guilin Jiqi e sebelisitse saponins e feletseng ea Gymnema sylvestre (bohloeki ba 98.2%) bakeng sa nts'etsopele ea litokisetso tsa lefu la tsoekere1; sehlopha sa bafuputsi sa India se ntšetsa pele liteko tsa pele tsa li-neuroprotective extracts;
Lijo tse phetseng hantle: li-extracts tsa makhasi li sebelisoa e le li-inhibitors tsa tlhaho tse monate bakeng sa lijo tse se nang tsoekere; li-extracts tsa stem ethanol li hlahisoa e le lino tse sebetsang bakeng sa ho laola tsoekere ea mali;
Lisebelisoa tsa temo: li-extracts tse tala tse tlaase li sebelisoa e le likokoanyana tse thehiloeng limela, tse lebisang tsamaiso ea methapo ea arthropods le ho ba le thepa e senyehang.
lNEWGREEN Supply High QualityGymnema Sylvestre ExtractPhofo
Nako ea poso: Jul-21-2025
