●Chii Gymnema Sylvestre Extract?
Gymnema sylvestre muzambiringa wemhuri yeApocynaceae, wakaparadzirwa zvakanyanya munzvimbo dzinopisa seGuangxi neYunnan kuChina. Kushandiswa kwemishonga yechivanhu kunonyanya kutariswa pamashizha ayo, ayo anoshandiswa kuderedza shuga yeropa, kudzivirira kuora kwezino uye kudzivisa kuita kutapira. Zvisinei, zvidzidzo zvenguva pfupi yapfuura zvakawana kuti zviwanikwa zvayo zvehunde zvakapfumawo muzvinhu zvinoshanda, uye matura acho anopeta kakapetwa kagumi pane emashizha. Kuburikidza nenzira yakarongeka yekuparadzanisa nzira, iyo n-butanol uye 95% ethanol zvikamu zve stem extracts zvakaratidza zvakafanana UV spectra uye dzakatetepa-layer chromatography maitiro kumashizha, zvichiratidza kuti zvinoshanda zvezviviri zvinowirirana zvakanyanya. Kuwanikwa uku kunopa tsigiro huru yekuwedzera dhaka dhaka uye kuderedza mutengo webudiriro.
Mushonga wemakemikari weGymnema sylvestre extractyakaoma uye yakasiyana, kunyanya kusanganisira:
Cyclols uye steroids:Conduritol A, seyo core hypoglycemic component, inogona kukurudzira glycogen synthesis; stigmasterol uye glucoside yayo ine anti-inflammatory regulatory effects;
Saponin makemikari:Muna 2020, masere matsva eC21 steroidal saponins (gymsylvestrosides AH) akaparadzaniswa kwekutanga, uye zvivako zvavo zvine glucuronic acid uye rhamnose units, zvichivapa zvakasiyana-siyana zvehupenyu;
Synergistic zvikamu:marefu-chain alkanols akadai se lupine cinnamyl ester uye n-heptadecanol inosimudzira antioxidant kugona nekubvisa mahara radicals.
Zvakakosha kuziva kuti kuchena kwe stem saponins kunogona kusvika kudarika 90%, uye kucheneswa kukuru kunogona kuwanikwa kuburikidza ne ethanol recrystallization teknolojia, kudzivisa kushandiswa kwemishonga ine chepfu yakadai sekloroform.
●Chii IzvoBenefitsOf Gymnema Sylvestre Extract?
1. Diabetes Management
Zvidzidzo zvePharmacological zvakaratidza kuti stem ethanol inobvisa inogona kuderedza mazinga eshuga yeropa ne30% -40% mualloxan diabetic mbeva, uye maitiro echiito anoratidza nzira dzakasiyana-siyana:
Kudzivirirwa kweIslet: gadzirisa akakuvadzwa β masero uye kuwedzera insulin secretion;
Glucose metabolism regulation: kukurudzira chiropa glycogen synthesis uye inhibit intestinal α-glucosidase basa (kunyange zvazvo inhibition rate ye monomer saponin inongova 4.9% -9.5%, iyo synergistic effect yezvinyorwa zvose zvakakosha);
Oxidative kusagadzikana kupindira: kuderedza lipid peroxide mazinga uye kuwedzera superoxide dismutase chiitiko.
2. Neuroprotection
Chidzidzo chakaburitswa muScientific Reports muna 2025 chakaratidza kugona kweGymnema sylvestreextractmukurapa kwechirwere cheAlzheimer (AD):
Kutarisa mapuroteni eAD anokosha: metabolites S-adenosylmethionine uye bamipine vane hukama hwepamusoro hwekubatanidza ne β-secretase (BACE1) uye monoamine oxidase B (MAO-B), kuderedza β-amyloid deposition;
Neural pathway regulation: nekuita cAMP/PI3K-Akt chiratidzo nzira, kuwedzera choline acetyltransferase (Chat) kutaura, apo kuderedza acetylcholinesterase basa, uye kunatsiridza synaptic transmission;
Kuongororwa kwekuongorora kwesero: Muiyo Aβ42-induced neural cell modhi, iyo yakatorwa yakaderedza chizvarwa che reactive oxygen marudzi (ROS) ne 40% uye apoptosis rate neinodarika 50%.
● Chii IzvoApplicationOf Gymnema Sylvestre Extract ?
Kubudirira kwemishonga: Guangxi Guilin Jiqi Kambani yakashandisa saponins yakazara yeGymnema sylvestre (kuchena 98.2%) pakuvandudza kugadzirira kwechirwere cheshuga1; Chikwata chekuIndia chekutsvagisa chiri kufambisira mberi miedzo yepamberi yezvinyorwa zvayo zveurouroprotective;
Chikafu chine utano: mashizha emashizha anoshandiswa sechisikigo kutapira inhibitors yezvokudya zvisina shuga; stem ethanol zvinyorwa zvinogadzirwa sezvinwiwa zvinoshanda zvekugadzirisa shuga yeropa;
Agricultural applications: low-purity crude extracts inoshandiswa semishonga inouraya zvipembenene, inonangana netsinga dzearthropods uye kuva nezvinhu zvinoora.
lNEWGREEN Supply High QualityGymnema Sylvestre ExtractUpfu
Nguva yekutumira: Jul-21-2025
