• NikiStreptococcus Thermophilus ?
Mu mateka maremare yo gutunga abantu mikorobe, Streptococcus thermophilus yabaye ubwoko bwibanze bwinganda z’amata hamwe n’ubushyuhe budasanzwe ndetse n’ubushobozi bwa metabolike. Mu 2025, ubushakashatsi buherutse gukorwa mu Ishuri Rikuru ry’Ubushinwa ry’inganda zita ku biribwa ndetse n’ishyirahamwe mpuzamahanga ry’amata (IDF) ryemeje bwa mbere ubwoko bw’ibinyabuzima byigenga ku rwego rwa genome ku nshuro ya mbere, ibyo bikaba ari intambwe nshya mu myumvire y’ubumenyi kuri iyi “zahabu y’amazi”. Nkibintu byingenzi byibikomoka ku mata asembuye hamwe n’umusaruro wa buri mwaka wa toni zirenga miliyoni 30 ku isi, Streptococcus thermophilus irenga imipaka gakondo kandi igashyiraho umurongo wo guhanga udushya mu biribwa bikora, ubuzima bw’ubuvuzi n’izindi nzego.
Streptococcus thermophilus yiswe Orla-Jensen bwa mbere mu 1919. Nyuma y’impaka z’amoko yagabanutse mu 1984 no kugarura amoko mu 1991, amaherezo yashyizeho imiterere y’ibinyabuzima byigenga binyuze mu buryo bwa genome zose (ANI ≥ 96.5%, dDDH ≥ 70%) mu 2025. Ubushinwa, Umuryango w’ubumwe bw’ibihugu by’Uburayi, Amerika FDA na IDF bifite umutekano. Muri 2025, integuro ya gatanu ya IDF “Urutonde rwa Bagiteriya y'ibiryo bisembuye” izuzuza ivugurura risanzwe.
Streptococcus thermophilus ni Gram-nziza, idakora spore, anaerobic ya facultative, hamwe nubushyuhe bwiza bwo gukura bwa 45-50 ° C, kwihanganira pH bingana na 3.5-8.5, hamwe nubushyuhe bukabije (igipimo cyo kubaho> 80% nyuma yo kuvurwa 85 ° C muminota 30).
• Ni izihe nyunguStreptococcus Thermophilus?
Ukurikije ubushakashatsi burenga 2000 ku isi, Streptococcus thermophilus yerekana agaciro k'ubuzima butandukanye:
1. Gucunga amara
Kugenzura ibimera bya bagiteri: Kubuza bagiteri gutera indwara mu gusohora bacteriocine (nka Salivaricine), byongera ubwinshi bwa bifidobacteria yo mu nda inshuro 2-3.
Gusana Mucosal: Kugenzura imiterere ya gene ya Gal3ST2, kugabanya fucosylation ya mucine colonique, no kugabanya imiti ya chimiotherapie iterwa no mu mara.
2. Amabwiriza ya Metabolic
Kugenzura isukari mu maraso: Kwivanga kwa bagiteri kwica ubushyuhe birashobora kugabanya isukari yamaraso yisonzesha ku mbeba za diyabete 23% kandi bikongerera insuline (indangagaciro ya HOMA-IR yagabanutseho 41%).
Cholesterol metabolism:Streptococcus thermophiluskubuza ibikorwa bya HMG-CoA kugabanya, kugabanya serumu LDL-C 8.4%, no kongera urwego rwa HDL-C.
3. Kongera ubudahangarwa
Amabwiriza ya Cytokine: Kangura IL-10 gusohora (kwibandaho byiyongereyeho inshuro 1.8), kubuza TNF-α (kugabanukaho 52%), no kugabanya uburibwe budakira.
Gukumira inzitizi ya Mucosal: Guteza imbere imvugo ya poroteyine zifatanije (ZO-1, Occludin) kandi bigabanya uburyo bwo mu mara (FITC-dextran yinjira yagabanutseho 37%).
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4. Ibishobora Kurwanya Kanseri
Kurwanya kanseri yibara: Gutesha kanseri binyuze mu nzira ya gal-galactosidase, bigabanya ibibyimba muri Apcmin / + imbeba 58%.
Indwara ya Apoptose: Ikora inzira ya Caspase-3, itera kwiyongera inshuro 4.3 igipimo cya apoptose ya selile kanseri ya HT-29.
Ni ubuhe buryo bukoreshwaStreptococcus Thermophilus?
Streptococcus thermophilus irenga imipaka gakondo kandi ikora matrix itandukanye:
Inganda z’amata
Yogurt / foromaje: ifatanije na Lactobacillus bulgaricus, igabanya igihe cya coagulation ikagera ku masaha 4 no kongera umusaruro ku bicuruzwa 15%.
Ibicuruzwa birimo isukari nke / ibinure bike: Binyuze muri tekinoroji ya EPS, ubukana bwa foromaje ifite amavuta make bwiyongera inshuro 2 kugirango bigereranye ibinure byuzuye.
2. Ibiryo bikora
Ibiryo bigenzurwa nisukari: ibinyampeke bya mugitondo hamwe nifu ya bagiteri 5% irashobora gutinza isukari yamaraso nyuma yinyuma yamasaha 1.5.
Immunoenhancer:Streptococcus thermophilushiyongereyeho oligofructose, ubwandu bw'imyanya y'ubuhumekero ku bana bwagabanutseho 33%.
3. Ubuzima bwo kwa muganga
Ibiryo byihariye byubuvuzi: bikoreshwa mugutegura imirire yimbere kugirango uzamure imirire yabarwayi ba chimiotherapie (albumin yiyongereyeho 1,2 g / dL).
Imiti ya porotiyotike: ifatanije na bifidobacteria mugutezimbere ibinini bivura IBS, hamwe nubutabazi bukabije bwa 78%.
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4. Ubuhinzi no Kurengera Ibidukikije?
Kugaburira ibiryo: Kugabanya igipimo cyimpiswi yingurube 42% no kongera igipimo cyibiryo 11%.
Gutunganya amazi mabi: Gutesha agaciro COD y’amazi y’amata ku kigero cya 65% no kugabanya umusaruro w’amazi 30%.
• Icyatsi gishya gitanga ubuziranengeStreptococcus ThermophilusIfu
Igihe cyoherejwe: Nyakanga-28-2025
