Ashwagandha Ibikururwa: Kwanga ikoreshwa rya "Umuhinde Ginseng"

●Niki Ashwagandha?

Mu bimera by'amayobera mu buvuzi bwa Ayurvedic bwo mu Buhinde bumaze imyaka 4000, Withania somnifera igaragara cyane ku miterere yihariye ya adaptogene. Iki gihingwa kizwi ku izina rya “Ginseng yo mu Buhinde”, cyateye imbere cyane binyuze mu ikoranabuhanga ry’ibinyabuzima bigezweho mu myaka yashize, kandi ibimera biva mu mizi byateje imbere inganda z’ubuzima ku isi. Ubushakashatsi buheruka gukorwa mu 2025 bwerekana ko ingano y’isoko rya Withania somnifera ikuramo yarenze miliyari 1,2 y’amadolari y’Amerika, aho buri mwaka izamuka rya 15%, rihinduka inyenyeri mu rwego rwo kurwanya umunaniro no kongera ubumenyi.

Ashwagandha ikwirakwizwa cyane mu turere twumutse two mu Buhinde na Afurika. Imizi yacyo ikungahaye ku bintu bifatika kandi akenshi bifatwa n'amata n'ubuki mu buvuzi gakondo bwa Ayurvedic.

Ashwagandhaikoresha Ethanol-amazi avanze na solvent hamwe nuburyo bwinshi bwo gukuramo ibicuruzwa kugirango utegure ibivuyemo muburyo butandukanye, kandi birashobora no gutegura monomer withanolide isanzwe.

Ashwagandhaikubiyemo ibice birenga 200, hamwe nibikorwa byingenzi birimo:

Withanolide (bingana na 1.5% -35%): nka Withaferin A na Withanolide D, bifite ingaruka zo kurwanya inflammatory na neuroprotective.

Alkaloide: nka Withanine, igenga ibikorwa bya reseptor ya GABA ikanagabanya amaganya.

Sterol: β-sitosterol ikomatanya yongerera imbaraga umubiri.

Ibintu bya fenolike: Ubushobozi bwo gusiba radicals yubusa bugera kuri DPPH IC50 = 34.4 μg / mL, bikaba byiza kuruta vitamine C.

● NikiInyunguByaAshwagandha ?

Ukurikije ibizamini birenga 120 byubuvuzi hamwe nubushakashatsi bwa molekuline,Ashwagandhayerekana agaciro k'ubuzima butandukanye:

1. Neuroenhancement

Gutezimbere ubwenge: 600 mg buri munsi mugihe cyibyumweru 8 bikurikiranye, kwibuka episodic byiyongereyeho 14.77%, ububiko bwakazi bwiyongereyeho 9.26% (amanota ya COMPASS).

Gukuraho igihu cyubwonko: Kunoza umuvuduko wo gutunganya amakuru yabarwayi ba MCI (byoroheje ubwenge buke) muguhuza inzira ya BDNF.

2. Gucunga Stress

Amabwiriza ya Cortisol:Ashwagandha rkugabanya imisemburo ya hormone igabanutseho 32% kandi ukoreshe uburyo bubi bwo gutanga ibitekerezo bya HPA.

Kunoza imitekerereze: Igipimo cya POMS cyerekana kugabanuka kwa 41% kumanota yo guhangayika no kwiheba, kandi byongera imbaraga hamwe imiti ya SSRI.

3. Amabwiriza ya Metabolic

Kurwanya indwara ya glycemic: Irabuza SGLT2 (IC50 = 9,6 kcal / mol) na α-glucosidase, kugabanya isukari yo mu maraso nyuma yo kubyara nyuma ya 37%.

Kwiyongera kwa testosterone: Serumu testosterone murwego rwabagabo yiyongereyeho 14.5%, itezimbere imikorere yimyororokere.

4. Ubudahangarwa no kurwanya gusaza

Kurwanya Antioxydeant: Yongera ibikorwa bya SOD inshuro 2,3 kandi igabanya IL-6 ibintu bitera 42%.

Kurinda Telomere: Ubushakashatsi bwa Epigenetike bwerekana ko bushobora kugabanya umuvuduko wo kugabanuka kwa telomere

● NikiGusabaOf Ashwagandha?

1. Ibiryo byongera ibiryo

Capsules / ibinini: Dose ya buri munsi 250-600mg, ibicuruzwa byuruhererekane rwa "Ubwonko bwa Sitasiyo" byatangijwe kubakozi.

Imirire ya siporo: Ugereranije na L-karnitine, itezimbere kwihangana 27% kandi igabanya imitsi.

2. Ibiryo bikora

Ibinyobwa bifasha gusinzira: Ongeraho 5%ashwagandhan'umuzi wa valeriya kugabanya igihe cyo gusinzira 58%.

Utubari twingufu: Gukomatanya ashwagandhahamwe na maca na guarana, guhora bitanga ingufu kumasaha 6.

3. Imyiteguro ya farumasi

Kuvura diyabete yiyongera: Hamwe na metformine, HbA1c igabanukaho 0.8%, bigabanya ibyago byo kurwara hypoglycemia.

Indwara zifata ubwonko: Uburyo bw'indwara ya Alzheimer bwerekana ko Aβ amyloide proteine ​​igabanukaho 39%.

4. Ibikoresho byo kwisiga byo kwisiga

Kurwanya gusaza: 0.1%ashwagandhaibuza ibikorwa bya MMP-1 kuri 63%, kugabanya iminkanyari yo gufotora.

Uruhu rworoshye rwo gusana: Igenga umuyoboro wa TRPV1, koroshya umutuku kuruta bisabolol

Icyatsi gishya gitanga ubuziranenge Ashwagandha Ifu