● What is Vitamin A Acetate ?
Retinyl Acetate, chemical name retinol acetate, molecular formula C22H30O3, CAS number 127-47-9, is an esterified derivative of vitamin A. Compared with vitamin A alcohol, it enhances stability through esterification reaction and avoids oxidative decomposition, becoming an important raw material in the fields of food, medicine and cosmetics.
Natural vitamin A is mainly found in animal liver and fish, but industrial production mostly adopts chemical synthesis, such as using β-ionone as a precursor and preparing it through Wittig condensation reaction. In recent years, green preparation technologies such as ultrasound-enhanced interfacial enzyme catalysis have emerged, significantly improving reaction efficiency and reducing pollution, becoming a key direction for industry technology upgrades.
Vitamin A acetate is a white to light yellow crystalline powder or viscous liquid with a melting point of 57-58°C, a boiling point of about 440.5°C, a density of 1.019 g/cm³, and a refractive index of 1.547-1.555. It has significant fat solubility and is easily soluble in organic solvents such as ethanol and ether, but has poor water solubility, and needs to be microencapsulated to improve its dispersibility in food.
In terms of stability, vitamin A acetate is sensitive to light, heat and oxygen, and needs to be stored away from light (2-8°C), and antioxidants such as BHT are added to extend the shelf life. Its bioavailability is as high as 80%-90%, and it is converted into retinol by enzymatic hydrolysis in the body and participates in physiological metabolism.
● What Are The Benefits Of Vitamin A Acetate?
1. Vision And Immune Regulation
As the active form of vitamin A, it participates in vision formation by converting to retinal, preventing night blindness and dry eye disease. At the same time, it enhances the barrier function of epithelial cells and reduces the risk of respiratory infections. Clinical trials have shown that it can improve children's immunity by 30%.
2. Skin Anti-Aging And Repair
Inhibits excessive proliferation of keratinocytes, promotes collagen synthesis, and reduces wrinkle depth by 40%. Adding 0.1%-1% concentration to cosmetics can improve photoaging and acne scars. For example, Lancome's Absolue series cream uses this as the core anti-aging ingredient.
3. Metabolism And Disease Adjuvant Treatment
Regulates lipid metabolism and lowers cholesterol levels. Animal experiments have shown that it can delay the progression of non-alcoholic fatty liver disease. In addition, in cancer adjuvant treatment, it shows potential application value by inducing tumor cell apoptosis.
● What Are The Applications Of Vitamin A Acetate ?
1. Food And Nutritional Enhancers
As a vitamin A enhancer, it is widely used in dairy products, edible oils and infant formula. Microencapsulation technology improves its stability during processing. The global annual demand exceeds 50,000 tons, and the Chinese market size is expected to reach US$226.7 million in 2030.
2. Cosmetics And Personal Care
Added vitamin a acetate to anti-aging essences, sunscreens and conditioners, such as SkinCeuticals moisturizing cream, it accounts for 5%-15%, and has both moisturizing and light protection functions. Its derivative retinol palmitate is more preferred for sensitive skin due to its mildness.
3. Pharmaceutical Preparations
Used to treat vitamin A deficiency and skin diseases (such as psoriasis), the oral dosage is 5000-10000 international units per day. New targeted delivery systems (such as liposomes) are being developed to improve efficacy.
4. Exploration Of Emerging Fields
In aquaculture, it is used as a feed additive to enhance fish immunity; in the field of environmental protection, its biodegradability is studied to develop sustainable packaging materials.
● NEWGREEN Supply Vitamin A Acetate Powder
Post time: May-21-2025
