●What is Quaternium-73 ?
Quaternium-73, also known as Pionin, is a thiazole quaternary ammonium salt compound with a chemical formula of C23H39IN2S2 and a CAS number of 15763-48-1. It is a light yellow to yellow odorless crystalline powder. Its molecular structure has the dual characteristics of strong antibacterial and inhibition of melanin production, and is known as the "golden ingredient for acne removal".
Compared with traditional preservatives (such as parabens), quaternary ammonium-73 has the following advantages:
Ultra-low dosage and high efficiency: The minimum inhibitory concentration (MIC) for Propionibacterium acnes is as low as 0.00002%, and the rash is reduced by 50% after two weeks of use. The whitening effect can completely inhibit melanin production at 0.1 ppm, which is better than kojic acid.
Stability and safety: High temperature and light resistance, wide pH range (5.5-8.0), zero sensitization, suitable for sensitive skin and post-medical beauty repair.
● What Are The Benefits Of Quaternium-73 ?
Quaternary ammonium salt-73 has become an "all-round player" in cosmetic formulas due to its unique biological activity:
Strong Anti-Acne Effect: Quaternium-73 is also effective against fungal acne by inhibiting Propionibacterium acnes and Malassezia. Clinical data show that the rash is reduced by 50% within two weeks.
Whitening And Anti-Freckle: Quaternium-73 Inhibits tyrosinase activity and blocks the melanin production pathway, with an effect dozens of times that of kojic acid.
Antibacterial And Antiseptic: Broad-spectrum antibacterial properties like Quaternium-73 can replace traditional preservatives, with a killing rate of over 90% for Staphylococcus aureus and Escherichia coli.
Anti-Inflammatory Repair: Quaternium-73 Reduces the release of inflammatory mediators, suitable for sensitive skin care such as dermatitis and redness after sun exposure.
● What Are The Applications Of Quaternium-73 ?
Skin Care Products
Anti-acne series: Add 0.002%-0.008% Quaternium-73 to oil-control essence and anti-acne mask to quickly reduce acne formation.
Whitening and sun protection: compounded Quaternium-73 with niacinamide and vitamin C to enhance the synergistic whitening effect; combined with zinc oxide to increase the SPF value of sunscreen.
Hair Care And Body Care
Adding Quaternium-73 to shampoo can inhibit scalp acne, and adding it to conditioner can repair frizzy hair.
Medical Field
Prescription ointment used to treat acne and dermatitis. Clinical studies show that it is 85% effective in repairing burns.
●Usage Suggestions:
Industrial Formula Recommendations
Dissolution method: Pre-dissolve with ethanol, butylene glycol or pentanediol, then add water or oil phase matrix to avoid agglomeration.
Recommended dosage: The maximum addition amount of Quaternium-73 in cosmetics is 0.002%, which can be increased to 0.01% in pharmaceutical preparations.
Product Development Case
Anti-acne essence: Quaternium-73 (0.005%) + salicylic acid (2%) + tea tree oil, oil control and antibacterial dual effects in one.
Whitening cream: Quaternium-73-73 (0.001%) + niacinamide (5%) + hyaluronic acid, taking into account both whitening and moisturizing.
As synthetic biology technology matures, microbial fermentation is expected to achieve mass production in 2026, reducing costs by 40%, and promoting the penetration of quaternary ammonium salt-73 from the high-end line to the mass market. At the same time, its application exploration in anti-tumor drug carriers and oral anti-glycation products will open up a new blue ocean of the health industry worth hundreds of billions of yuan.
Under the dual concepts of functional skin care and green consumption, Quaternium-73, a "golden molecule", is becoming the core driving force for industry upgrading, bringing safer and more efficient skin solutions to global users.
●NEWGREEN Supply Quaternium-73 Powder
Post time: May-07-2025
