What is Pumpkin Seed Extract ?
Pumpkin seed extract is derived from the mature seeds of Cucurbita pepo, a plant of the Cucurbitaceae family. Its medicinal history can be traced back to the Compendium of Materia Medica more than 400 years ago, and was praised by Li Shizhen as a “nutritious tonic”. Modern preparation technology achieves high retention of active ingredients through continuous phase change extraction (CPE) and supercritical CO₂ extraction. For example, CPE technology can increase the extraction rate to 96.75% under 46°C and 0.51 MPa, which is 35.24% higher than the traditional screw pressing method, while retaining active substances such as total phenols and sterols to the maximum extent. In the global industrialization layout, Shaanxi, Sichuan and other places in China have become core production areas, relying on GAP planting bases and GMP production lines to promote raw material standardization and sustainable development.
The efficacy of pumpkin seed extract comes from its unique combination of chemical components:
1.Δ-7 Sterol: a rare plant sterol that can inhibit 5α-reductase activity, reduce dihydrotestosterone (DHT) levels, and relieve prostate hyperplasia.
2.Cucurbitine: Alkaloid compound, core anthelmintic ingredient, paralyzing tapeworm and schistosoma larvae.
3.Unsaturated Fatty Acids: linoleic acid and oleic acid account for 82.32%, regulating lipid metabolism and lowering cholesterol.
4.Antioxidant Network: Total phenol content reaches 1333.80 mg/kg (CPE method), synergistically with carotenoids (8.41 mg/kg) to scavenge free radicals, with an efficiency 4 times that of vitamin E.
5.Trace Elements: Zinc content is 9.61 mg/100g, supporting prostate health and immune regulation.
What Are The Benefits Of Pumpkin Seed Extract ?
1. Guardian Of Men’s Health
Prostate hyperplasia relief: Clinical studies have shown that daily intake of oil-free hydrolyzed pumpkin seed ethanol extract can reduce the frequency of nocturnal urination by 30.1% and significantly reduce residual urine volume within 3 months. The mechanism is related to the inhibition of 5α-reductase by Δ-7 sterols. In animal experiments, 500 mg/kg pumpkin seed alkaloids can reduce the wet weight of the prostate to near normal levels.
2. Deworming And Intestinal Protection
Natural parasite inhibitor: Pumpkin seed alkaloids eliminate microscopic tapeworm infections by paralyzing the middle and posterior segments of tapeworms, and the damage to the intestinal mucosa is much lower than that of the chemical drug praziquantel.
3. Skin And Metabolic Regulation
Oil control and anti-acne: Water-soluble pumpkin seed extract DISAPORETM (added amount 0.5%-2.5%) inhibits the activity of sebaceous glands. Clinical trials have confirmed that it can turn oily skin into neutral and reduce pore blockage.
Antioxidant and lipid-lowering: Flavonoids reduce malondialdehyde (MDA) by 38.5%, increase superoxide dismutase (SOD) activity by 67.6%, and regulate triglyceride metabolism.
4. Aquaculture Revolution
Adding 4% pumpkin seed extract to carp feed increases weight gain by 155.1%, reduces feed conversion rate to 1.11, increases lysozyme activity to 69.2 U/mL, and enhances lipase activity by 38%, providing a new solution for antibiotic replacement.
What Are The Applications Of Pumpkin Seed Extract ?
1. Medicine And Health Products
Prostate health preparations: capsules or oral liquids are used for the management of benign prostatic hyperplasia (BPH), and the effectiveness of products in the German market exceeds 41.6%.
Antiworm drugs: compounded with betel nut to treat tapeworm disease, the deworming rate reaches 90%.
2. Cosmetics And Personal Care
Oil control products: DISAPORETM is used in anti-acne essences and scalp care liquids to regulate oil secretion.
Anti-aging repair: antioxidant ingredients are integrated into sunscreens and night creams to reduce photoaging damage.
3. Aquaculture And Animal Husbandry
Functional feed additives: enhance fish immunity and reduce breeding costs. Global aquaculture trials cover economic species such as carp and tilapia.
4. Functional Foods
Added to meal replacement powders and liver protection tablets to assist in regulating blood sugar and blood lipids, such as Japan’s anti-glycation oral liquid.
NEWGREEN Supply Pumpkin Seed Extract Powder
Post time: May-28-2025



