● What Is Polygonum Multiflorum Extract ?
Polygonum multiflorum is a twining vine of the Polygonaceae family. Its root epidermis is reddish brown to dark brown, and the cross section is densely covered with round vascular bundles. It is mainly produced in the mountainous areas of the Yangtze River Basin in Shaanxi, Gansu, Yunnan and other places in China. Traditional excavation must be carried out in summer and autumn to retain the active ingredients. Modern extraction uses 70% ethanol reflux technology. After three extractions, it is concentrated and spray-dried to obtain a brown-yellow powder, in which the core active ingredient stilbene glycoside content can reach 8%-95% (HPLC method).
Among the 1,186 metabolites of Polygonum multiflorum extarct, three major categories of components have shown efficacy:
1. Stilbene glycosides: 2,3,5,4′-tetrahydroxystilbene glycoside, neuroprotection, inhibition of β-amyloid protein toxicity, and improvement of learning and memory ability of Alzheimer’s model mice by 40%
2. Anthraquinone derivatives: emodin, chrysophanol, and rhein, which have antibacterial effects and an inhibition rate of more than 90% on Staphylococcus aureus; they can also reduce lipids and block key enzymes in cholesterol synthesis.
3. Lecithin: Phosphatidylcholine, repairs fatty liver cell membrane; anti-aging, improves lymphocyte 3DNA repair ability.
Key discovery: A university experiment confirmed that stilbene glycoside (100mg/kg) can reduce MDA (lipid peroxide) in the brain tissue of aging rats by 50% and increase SOD activity by 2 times, but exceeding 300mg/kg will induce transaminase abnormalities.
● What Are The Benefits Of Polygonum Multiflorum Extract ?
1. Scalp Health
Anti-hair loss, black hair: stilbene glycoside activates the tyrosinase activity of hair follicle melanocytes.
Anti-aging barrier: Lecithin repairs the scalp stratum corneum, reduces the production of lipid peroxides, and makes hair care products have additional anti-aging effects.
2. Intervention Of Neurodegenerative Diseases
Targeted removal of β-amyloid protein: stilbene glycoside blocks its binding to neurons, reducing the cell apoptosis rate by 35%;
Regulate apoptosis genes: Upregulate Bcl-2 expression, inhibit Caspase-3 pathway, and delay aging of the cerebral cortex.
3. Metabolic Syndrome Regulation
Lipid reduction: Prepared Polygonum multiflorum alcohol extract (0.84g/kg) reduces quail plasma triglycerides by 40% within 6 weeks;
Heart protection: Reduce myocardial ischemia-reperfusion injury by activating SOD enzyme.

● What Are The Applicat
Anti-aging cosmetics: It can be added to essence as a SOD activator, and its efficiency in inhibiting skin lipid peroxidation is 3 times that of ordinary VE
Functional food: Polygonum multiflorum + γ-aminobutyric acid compound capsules, with an effective rate of 80% in improving menopausal insomnia.
● Polygonum multiflorum extract recommendations:
Oral
Dosage control: The recommended daily intake should be adjusted according to individual constitution, usually not more than 3 times/week, to avoid excessive liver damage.
Time of use: It is best to take after meals to avoid irritating the gastrointestinal tract on an empty stomach.
Compatibility recommendations: It can be decocted with Chinese wolfberry, red dates, angelica and other medicinal materials to enhance the tonic effect.
External use
Skin care: The antioxidant and anti-inflammatory properties of the extract can be used to repair skin damage, but a small-scale test is required first to avoid allergies.
Precautions: It is forbidden to use on ulcerated or sensitive skin, and avoid direct contact.
● Newgreen Supply High Quality Polygonum Multiflorum Extract Powder
Post time: Jul-14-2025

