What is Kojic Acid Dipalmitate?
Introduction to raw materials: Innovation from kojic acid to fat-soluble derivatives
Kojic acid dipalmitate (CAS No.: 79725-98-7) is an esterified derivative of kojic acid, which is prepared by combining kojic acid with palmitic acid. Its molecular formula is C₃₈H₆₆O₆ and its molecular weight is 618.93. Kojic acid was originally derived from the fermentation products of fungi such as Aspergillus oryzae and is widely used in food preservation and whitening, but its water solubility and instability to light, heat and metal ions limit its application. Kojic acid dipalmitate is modified by esterification, which not only retains the whitening activity of kojic acid, but also significantly improves its stability and fat solubility, making it a star ingredient in the cosmetics industry.
Its preparation process includes chemical synthesis and bioenzymatic hydrolysis technology. Modern technology optimizes reaction conditions (such as high-temperature esterification or enzyme catalysis) to ensure that the product purity is ≥98% and meets cosmetic-grade quality standards.
Kojic acid dipalmitate is a white to light yellow crystalline powder with a melting point of 92-96°C and a density of 0.99 g/cm³. It is soluble in mineral oil, esters and hot ethanol, but insoluble in water. The hydroxyl groups in its molecular structure are esterified, which avoids hydrogen bonding with other ingredients in cosmetics (such as preservatives and sunscreens) and improves compounding performance.
What Are The Benefits Of Kojic Acid Dipalmitate?
Kojic acid dipalmitate achieves skin care effects through multiple mechanisms:
Highly effective whitening
Inhibit tyrosinase activity: By chelating copper ions (Cu²⁺), it blocks the melanin production pathway, and has a stronger whitening effect than kojic acid. Clinical data show that its melanin inhibition rate can reach more than 80%.
Lighten spots: Kojic Acid Dipalmitate has a significant improvement effect on pigmentation such as age spots, stretch marks, freckles, etc.
Antioxidant and anti-aging
It has outstanding free radical scavenging ability, reduces ultraviolet-induced oxidative damage, delays collagen degradation, and assists in anti-wrinkle.
Mildness and safety
It is listed as a safe cosmetic raw material by the US CTFA, the EU and the China Food and Drug Administration. It is non-irritating and suitable for sensitive skin.
What Are The Applications Of Kojic Acid Dipalmitate?
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Post time: Nov-13-2026