● What is Glutathione ?
Glutathione (GSH) is a tripeptide compound (molecular formula C₁₀H₁₇N₃O₆S) formed by glutamic acid, cysteine and glycine connected by γ-amide bonds. Its active core is the sulfhydryl group (-SH) on cysteine, which gives it strong reducing ability.
Two major physiological types of glutathione:
1. Reduced glutathione (GSH): accounts for more than 90% of the total amount in the body and is the main form of antioxidant and detoxification functions; directly removes free radicals and protects cells from oxidative damage.
2. Oxidized glutathione (GSSG): formed by the oxidation of two molecules of GSH (G-S-S-G), with weak physiological activity; under the catalysis of glutathione reductase, it depends on NADPH to be reduced to GSH to maintain cellular redox balance.
● What Are The Benefits Of The Glutathione ?
1. Core Physiological Functions
Detoxification and liver protection:
Glutathione can chelate heavy metals (lead, mercury), drug toxins (such as cisplatin) and alcohol metabolites. Intravenous injection of 1800mg/day can significantly improve liver function, and the effective rate of treating alcoholic liver disease is over 85%.
Auxiliary anti-tumor:
Glutathione can reduce chemotherapy nephrotoxicity, increase the activity of natural killer cells (NK cells) by 2 times, and inhibit tumor cell oxidative stress.
Neurological and ophthalmic protection:
Glutathione can relieve early symptoms of Parkinson’s disease and reduce dopamine neurotoxicity; local application of eye drops can repair corneal ulcers and inhibit the development of cataracts.
2. Health And Beauty Applications
Anti-aging immune regulation: Activate Sirtuins protein and delay telomere shortening; enhance lymphocyte function and reduce the release of inflammatory factors;
Whitening and spot removal: Inhibit tyrosinase activity and reduce melanin production. Clinically proven to improve skin elasticity and reduce wrinkle depth by 40%.
●What Are The Applications Of Glutathione ?
1. Medical Field
Injection: used for chemotherapy protection (1.5g/m² dose), acute poisoning first aid, and needs to be stored away from light;
Oral preparations: long-term use (200-500mg/time, more than 6 months) to increase the body’s GSH reserves and assist in the treatment of chronic liver disease.
2. Functional Food
Antioxidant supplements: compound vitamin C (500mg vitamin C per day can increase GSH levels by 47%) or selenium to enhance immunity;
Hangover and liver protection food: added glutathione to functional beverages to accelerate alcohol metabolism and reduce liver damage.
3. Cosmetic Innovation
Whitening essence: widely used in the Asian market to inhibit melanin, combined with microneedle technology to improve skin penetration;
Anti-aging formula: liposome encapsulated GSH resists ultraviolet damage and reduces photoaging erythema by 31%-46%.
4. Application Of Emerging Technologies
Targeted drug delivery: GSH-responsive nanogels can controllably release chemotherapy drugs (such as doxorubicin) at the tumor site, improving efficacy and reducing side effects;
Environmental protection and agriculture: Develop biodegradable materials and explore feed additives to enhance livestock and poultry immunity.
From the patent of yeast extraction to the mass production of thousands of tons in synthetic biology today, the industrialization process of glutathione has confirmed the transformation of “cell guardian” to “technology engine”. In the future, with the completion of clinical verification of new indications of neuroprotection and anti-aging, this life-carrying antioxidant molecule will continue to provide scientific momentum for human health and longevity.
● NEWGREEN Supply Glutathione Powder
Post time: Jun-23-2025
