●What Is Hydroxycitric Acid ?
Hydroxycitric Acid (HCA) is the core active substance in the peel of Garcinia cambogia. Its chemical structure is C₆H₈O₈ (molecular weight 208.12). It has one more hydroxyl group (-OH) at the C2 position than ordinary citric acid, forming a unique metabolic regulation ability. Garcinia cambogia is native to India and Southeast Asia. Its dried peel has long been used as a curry seasoning, and modern extraction technology can concentrate 10%-30% of HCA from it. In 2024, China’s patented technology (CN104844447B) increased the purity to 98% through low-temperature high-shear extraction + nanofiltration desalination process, solving the problem of impurity residues in traditional acid hydrolysis.
Physical And Chemical Properties of Hydroxycitric Acid :
Appearance: white to light yellow crystalline powder, slightly sour taste;
Solubility: easily soluble in water (>50mg/mL), slightly soluble in ethanol, insoluble in non-polar solvents;
Stability: sensitive to light and heat, easy to degrade when pH <3, need to be stored away from light and at low temperature (<25℃);
Detection standard: high performance liquid chromatography (HPLC) to determine the content, the purity of high-quality extract HCA should be ≥60%.
●What Are The Benefits Of Hydroxycitric Acid ?
HCA achieves fat loss through a triple pathway, and is especially suitable for people on a high-carb diet:
1. Inhibit Fat Synthesis
Competitively binds to ATP-Citrate Lyase, blocking the pathway for acetyl-CoA to convert into fat;
Clinical studies have shown that it reduces fat synthesis by 40%-70% within 8-12 hours after a meal.
2. Promote Fat Burning
Activates the AMPK signaling pathway and accelerates fatty acid β-oxidation in muscle and liver;
The average body fat percentage of subjects decreased by 2.3% in the 12-week trial.
3. Regulate Appetite
Increase brain serotonin (5-HT) levels and reduce high-calorie food intake;
Synergizes with plant cellulose to enhance stomach satiety.
●What Are The Application Of Hydroxycitric Acid ?
1. Weight Management:
As a core ingredient in weight loss capsules and meal replacement powders, the recommended dose is 500-1000 mg/day (taken in 2-3 times);
Combined with L-carnitine and caffeine, it can enhance the fat burning effect.
2. Sports Nutrition:
Improve endurance performance and reduce fatigue after exercise, suitable for athletes and fitness people.
3. Metabolic Health:
Improve insulin sensitivity and assist in regulating blood sugar and blood lipids (LDL-C is reduced by about 15%).
4.Food Industry:
As a natural acidifier used in low-sugar beverages, it also has the function of regulating metabolism.
●Tips:
1. Adverse reactions:
High doses of hydroxycitric acid (>3000mg/day) may cause headaches, nausea, and gastrointestinal discomfort;
Long-term use requires monitoring of liver function (a few cases reported elevated transaminases).
2. Contraindications:
Pregnant women and lactating women (insufficient safety data);
Diabetic patients (combination with hypoglycemic drugs may cause hypoglycemia);
Psychotropic drug users (5-HT regulation may affect drug efficacy).
3. Drug interactions:
Avoid combined use with antidepressants (such as SSRIs) to prevent the risk of 5-HT syndrome.
●NEWGREEN Supply High Quality Hydroxycitric Acid Powder
Post time: Jul-08-2025
