● What Is Albizia Bark Extract ?
The bark of Albizia julibrissin is the dried bark of the leguminous plant Albizia julibrissin, and it is mainly produced in the provinces along the Yangtze River such as Hubei, Jiangsu and Zhejiang. Its epidermis is densely covered with brownish-red oval-shaped pores, resembling “pearl lumps”. The inner cross-section is fibrous and flaky, with a slightly astringent and pungent taste. Traditional harvesting and peeling should be completed in summer and autumn to maintain the stability of active ingredients.
Introduction to the ingredients of Albizia bark extract:
The bark of the silk tree contains 1,186 metabolites. The core active component is triterpene saponins (accounting for 15%-30% of the dry weight), supplemented by flavonoids, lignans and polysaccharides.
Anti-tumor pioneer: Achuan glycoside (C₅₈H₉₄O₂₆) inhibits tumor neovascularization by blocking vascular endothelial growth factor receptor (VEGFR-2);
Immune enhancer: The polysaccharide component activates the phagocytic function of macrophages, enhances the activity of interleukin-2 (IL-2), and inhibits the transplanted S180 sarcoma in mice by 73%.
Neuroregulatory factors: 3 ‘,4 ‘, 7-trihydroxyflavonoids regulate the gamma-aminobutyric acid (GABA) pathway, reducing the sleep time of insomnia model mice by 40%.
Breakthrough discovery: A 2024 study confirmed that component 23 (ethanol reflux – n-butanol extract) can induce cell nucleus consolidation and necrosis in tumor cells, and its liver and kidney toxicity in tumor-bearing mice is reduced by 50% compared to traditional extracts.
● What Are The Benefits Of Albizia Bark Extract ?
1. Anti-Tumor Angiogenesis
Inhibiting the migration of HMEC-1 endothelial cells and blocking the nutrient supply to tumors, preclinical trials have shown that the area of metastatic foci has decreased by 60%.
When used in combination with the chemotherapy drug avastin, it can reduce the subcutaneous injection dosage by 70%, breaking the bottleneck of oral bioavailability.
2. Psychoneuroregulation
Relieving depression and calming the mind: Up-regulating the expression of 5-hydroxytryptamine receptors and improving the frequency of spontaneous activities in anxiety model rats;
Anticonvulsant: Albizia bark extract can reduces the excitability of glutamatergic neurons, and the frequency of epileptic seizures decreases by 35%.
3. Traditional Efficacy Upgrade
Anti-lung abscess: Quercetin 3-O-galactoside inhibits the formation of septic bacteria biofilms, and the inflammatory factor TNF-α in lung tissue decreases by 52%.
Trauma repair: Tannin components activate osteoblasts, increasing the formation rate of callus in fractured rats by 40%.
● What Are The Application Of Albizia Bark Extract ?
1. Medical Field
Tumor-targeted drugs: Some pharmaceutical enterprises are promoting the application for new drugs of the fifth category of traditional Chinese medicine with component 23, which are intended for the adjuvant treatment of glioma.
Mental health products: A Japanese enterprise has developed a compound capsule of Acacia glycoside and γ -aminobutyric acid, with an effective rate of over 80% in improving insomnia during menopause.
2. Functional Foods And Cosmetics
Calming tea drink: Albizia bark extract (10:1 concentrated) combined with jujube seed, with a repurchase rate of 65% on the Tmall flagship store.
Anti-allergy skin care: The flavonoid components inhibit the degranulation of mast cells. Some cosmetic enterprises have launched “Hehuan Soothing Essence”.
3. Agricultural Innovation
The crude extract of silk tree bark, as a plant-based insecticide, has a 92% fatality rate against aphids and a degradation cycle of only 7 days.
● Newgreen Supply High Quality Albizia Bark Extract Powder
Post time: Jul-14-2025
