Tauroursodeoxycholic acidTUDCA), a matsayin abin da aka samo asali na bile acid na halitta, ya zama abin da masana'antun kiwon lafiya na duniya suka mayar da hankali a cikin 'yan shekarun nan saboda mahimmancin kariyar hanta da tasirin neuroprotection. A cikin 2023, girman kasuwar TUDCA ta duniya ya zarce dalar Amurka miliyan 350, kuma ana tsammanin ya kai dalar Amurka miliyan 820 a cikin 2030, tare da haɓaka haɓakar shekara-shekara na 12.8%. Kasuwannin Turai da Amurka sun mamaye babban adadin shigar kayayyakin kiwon lafiya. Yankin Asiya-Pacific (musamman China da Indiya) ne ke jagorantar duniya cikin haɓakar haɓaka yayin da cututtukan hanta na yau da kullun ke ƙaruwa da haɓaka amfani da lafiya.
Bayan haka, bisa ga haƙƙin mallaka na Besty Pharmaceuticals, TUDCA na iya inganta haɓakar tsarin cututtukan cututtukan cututtukan cututtukan ƙwayoyin cuta ta hanyar hana apoptosis neuronal da rage damuwa mai ƙarfi. Bugu da ƙari, zurfin aikace-aikacen fasaha na AI a cikin bincike da ci gaba na miyagun ƙwayoyi (kamar binciken da aka yi niyya da haɓaka gwajin gwaji) ya haɓaka ingantaccen canjin asibiti na TUDCA, kuma ana sa ran girman kasuwar da ta dace ya wuce dalar Amurka biliyan 1 a cikin shekaru biyar masu zuwa.
●Hanyar shiri: daga hakar al'ada zuwa haɗin kore
1. Hanyar Hakar Gargajiya:Ursodeoxycholic acid (UDCA) yana rabu da bile na bear, sannan a haɗe shi da taurine don samar da shi.TUDCA. Iyakance ta hanyar ka'idodin kariyar dabba da ƙarfin samarwa, farashin yana da yawa kuma ana canza shi a hankali.
2. Hanyar Haɗin Sinanci:Yin amfani da bile acid a matsayin albarkatun kasa, UDCA an haɗa shi ta hanyar hadawan abu da iskar shaka, ragewa, condensation da sauran matakai, sa'an nan kuma taurized. Tsabta na iya kaiwa fiye da 99%, amma tsarin yana da rikitarwa kuma gurbatawa yana da girma.
3. Hanyar Haihuwar Kwayoyin cuta (Tsarin Gaba):Yin amfani da Escherichia coli da aka kirkira ta kwayoyin halitta ko yisti don haɗa kai tsayeTUDCA, yana da abũbuwan amfãni daga kore, low-carbon da kuma babban taro samar m. A cikin 2023, Kamfanin BioCore a Koriya ta Kudu ya sami nasarar samar da matukin jirgi, yana rage farashin da kashi 40%.
4. Hanyar Catalysis Enzyme:Fasahar enzyme mara motsi na iya inganta haɓakar haɗin gwiwar UDCA da taurine, kuma yanayin halayen yana da sauƙi, wanda ya dace da samar da magunguna.
●Amfani: Multi-manufa tsarin aiki, rufe da fadi da kewayon cututtuka
Tushen tsarin TUDCA shine don daidaita membrane tantanin halitta, hana damuwa na endoplasmic reticulum da hanyoyin siginar apoptosis, kuma an tabbatar da shi ta asibiti a lokuta da yawa:
1. Cututtukan Hanta:
⩥ Maganin farko na biliary cholangitis (PBC), cututtukan hanta maras giya (NAFLD), da rage alamun ALT/AST.
Yana kawar da cholestasis kuma yana inganta metabolism na bilirubin. FDA ta amince da matsayinta na magungunan marayu.
2. Kariyar Neuro:
⩥ Inganta lalacewar neuronal a cikin cutar Alzheimer da cutar Parkinson. Nazarin yanayi na 2022 ya nuna cewa zai iya rage jigon β-amyloid.
⩥ Ya nuna yuwuwar jinkirta yanayin cutar a cikin gwaje-gwajen asibiti na ciwon ƙwayar cuta na amyotrophic (ALS).
3. Metabolism Da Anti-tsufa:
⩥ Daidaita hankalin insulin da kuma taimakawa wajen sarrafa ciwon sukari.
⩥ Kunna aikin mitochondrial, tsawaita tsawon rayuwar kwayoyin halitta, kuma zama ɗan takarar ɗan takara don "magungunan tsawon rai".
4. Aikace-aikacen Ophthalmic:
⩥ Yana da tasirin kariya akan retinitis pigmentosa da glaucoma, kuma ruwan ido masu alaƙa sun shiga gwajin asibiti na Phase III.
●TUDCA wuraren aikace-aikacen: daga magani zuwa abinci mai aiki
1. Filin Kiwon Lafiya:
⩥ Magungunan magani: TUDCA da ake amfani da su don PBC, rushewar gallstone (kamar shirye-shiryen Taurursodiol na Turai).
⩥ Marayu da miyagun ƙwayoyi ci gaban: hade far ga rare cututtuka irin su spinal muscular atrophy (SMA).
2. Kayayyakin Lafiya:
⩥ Allunan kariya na hanta, samfuran hanta: TUDCAza a iya amfanitare da silymarin da curcumin don haɓaka sakamako.
⩥ Capsules Anti-tsufa: hade tare da NMN da resveratrol, mai da hankali kan gyaran mitochondrial.
3. Abincin Wasanni:
⩥ Rage ƙumburi na tsoka bayan horo mai tsanani, ana amfani da shi azaman ƙarin farfadowa ta hanyar ƙwararrun 'yan wasa.
4. Lafiyar dabbobi:
⩥ Jiyya da kula da lafiyar hanta da cututtukan gallbladder a cikin karnuka da kuliyoyi, samfuran da ke da alaƙa a cikin kasuwar Amurka za su haɓaka da kashi 35% a cikin 2023.
Tare da karuwar yawan tsufa da yawan cututtukan cututtuka na rayuwa, ƙimar TUDCA a fagen magani, kiwon lafiya, da kuma tsufa za a kara saki. Fasahar nazarin halittun roba na iya haɓaka farashi mai araha da buɗe kasuwar kiwon lafiya mai daraja ɗaruruwan biliyoyin yuan.
●SABON KYAUTATUDCAFoda
Lokacin aikawa: Afrilu-15-2025
