●Menene Gymnema Sylvestre Extract?
Gymnema sylvestre itace itacen inabi na dangin Apocynaceae, wanda aka rarraba a yankuna masu zafi kamar Guangxi da Yunnan na kasar Sin. Amfanin maganin gargajiya ya fi maida hankali ne akan ganyensa, waɗanda ake amfani da su don rage sukarin jini, hana ruɓar haƙori da hana halayen ɗanɗano mai daɗi. Duk da haka, binciken da aka yi kwanan nan ya gano cewa albarkatun sa suna da wadata a cikin kayan aiki masu aiki, kuma ajiyar sun fi sau 10 fiye da ganye. Ta hanyar tsarin rabuwa da sauran ƙarfi, n-butanol da 95% ethanol sassa na ɓangarorin tushe sun nuna irin sifofin UV da sifofin chromatography na bakin ciki ga ganye, yana nuna cewa abubuwan da ke aiki na biyun sun daidaita sosai. Wannan binciken yana ba da tallafi mai mahimmanci don faɗaɗa tushen magunguna da rage farashin ci gaba.
A sinadaran abun da ke ciki naGymnema sylvestre cireyana da rikitarwa kuma ya bambanta, musamman ya haɗa da:
Cyclols da steroids:Conduritol A, a matsayin core hypoglycemic bangaren, na iya inganta glycogen kira; stigmasterol da glucosides suna da tasirin maganin kumburi;
Saponin mahadi:A cikin 2020, sabbin saponins na C21 steroidal guda takwas (gymsylvestrosides AH) an keɓe su a karon farko, kuma tsarin su yana ɗauke da glucuronic acid da raka'a rhamnose, yana ba su ayyukan ilimin halitta na musamman;
Abubuwan haɗin gwiwa:Alkanols masu tsayin sarka irin su lupine cinnamyl ester da n-heptadecanol suna haɓaka ƙarfin antioxidant ta hanyar lalata radicals kyauta.
Ya kamata a lura da cewa tsarkin kara saponins zai iya kai fiye da 90%, kuma za a iya samun babban-sikelin tsarkakewa ta hanyar ethanol recrystallization fasahar, guje wa amfani da mai guba kaushi kamar chloroform.
●Menene TheAmfaniNa Gymnema Sylvestre Extract?
1. Gudanar da Ciwon suga
Nazarin pharmacological ya nuna cewa tsantsa ethanol na iya rage matakan sukari na jini da kashi 30% -40% a cikin ɓerayen masu ciwon sukari na alloxan, kuma tsarin aikin yana nuna haɓakar hanyoyi da yawa:
Kariyar tsibiri: gyara sel β da suka lalace kuma suna haɓaka haɓakar insulin;
Tsarin metabolism na glucose: inganta haɓakar hanta glycogen kuma yana hana ayyukan α-glucosidase na hanji (ko da yake ƙimar hanawar saponin na monomer shine kawai 4.9% -9.5%, tasirin synergistic na duka tsantsa yana da mahimmanci);
Saɓanin damuwa na Oxidative: rage matakan peroxide na lipid kuma ƙara yawan aikin dismutase na superoxide.
2. Neuroprotection
Wani bincike da aka buga a cikin Rahoton Kimiyya a cikin 2025 ya nuna yuwuwarGymnema sylvestrecirea cikin maganin cutar Alzheimer (AD):
Ƙaddamar da sunadaran AD mai mahimmanci: metabolites S-adenosylmethionine da bamipine suna da alaƙa da haɗin gwiwa tare da β-secretase (BACE1) da monoamine oxidase B (MAO-B), rage β-amyloid deposition;
Ka'idodin hanyoyin jijiyoyi: ta hanyar kunna hanyar siginar cAMP / PI3K-Akt, haɓaka maganganun choline acetyltransferase (Chat), yayin da rage ayyukan acetylcholinesterase, da haɓaka watsa synaptic;
Tabbatar da gwajin ƙwayar cuta: A cikin ƙirar ƙwayoyin jijiyoyi da aka haifar da Aβ42, tsantsa ya rage samar da nau'in oxygen mai amsawa (ROS) da 40% da ƙimar apoptosis fiye da 50%.
● Menene TheAikace-aikaceOf Gymnema Sylvestre Extract ?
Ci gaban Magunguna: Kamfanin Guangxi Guilin Jiqi ya yi amfani da jimlar saponins na Gymnema sylvestre (tsarki 98.2%) don haɓaka shirye-shiryen masu ciwon sukari1; ƙungiyar bincike ta Indiya tana ci gaba da gwaje-gwajen gwaje-gwaje na abubuwan da suka dace na neuroprotective;
Abinci mai lafiya: Ana amfani da tsantsar ganye azaman masu hana zaƙi na halitta don abinci marasa sukari; an haɓaka tsantsa ethanol azaman abubuwan sha masu aiki don daidaita sukarin jini;
Aikace-aikacen aikin noma: ana amfani da tsattsauran ɗanyen mai ƙarancin tsabta azaman tsire-tsire masu tsire-tsire, suna yin niyya ga tsarin juyayi na arthropods da samun kaddarorin lalacewa.
lNEWGREEN Samar da Ingantaccen inganciGymnema Sylvestre ExtractFoda
Lokacin aikawa: Yuli-21-2025
