I-Vitamin A Acetate: Isithako Sokuguga Sezithako Ezinomsoco kanye Nezimonyo

●Yini I-Vitamin A Acetate?

I-Retinyl Acetate, igama lekhemikhali i-retinol acetate, ifomula yamangqamuzana C22H30O3, inombolo ye-CAS 127-47-9, iphuma esterified kavithamini A. Uma iqhathaniswa ne-vitamin A utshwala, ithuthukisa ukuzinza ngokusabela kwe-esterification futhi igwema ukubola kwe-oxidative, ibe impahla eluhlaza ebalulekile emikhakheni yezokwelapha, ye-cosmetics.

 

Uvithamini A wemvelo utholakala kakhulu esibindini sesilwane nasezinhlanzini, kodwa ukukhiqizwa kwezimboni ngokuvamile kusebenzisa ukuhlanganiswa kwamakhemikhali, njengokusebenzisa i-β-ionone njengesandulela nokuyilungisa ngokusabela kwe-Wittig condensation. Eminyakeni yamuva nje, ubuchwepheshe bokulungiselela obuluhlaza obufana ne-ultrasound-enhanced interfacial enzyme catalysis kuye kwavela, kuthuthukisa kakhulu ukusebenza kahle kokusabela nokunciphisa ukungcola, kube isiqondiso esibalulekile sokuthuthukiswa kobuchwepheshe bemboni.

 

I-Vitamin A acetatei-crystalline powder emhlophe kuya kokuphuzi ngokukhanyayo noma uketshezi lwe-viscous olunephuzu lokuncibilika elingu-57-58°C, indawo yokubilisa engaba ngu-440.5°C, ukuminyana okungu-1.019 g/cm³, kanye nenkomba ye-refractive engu-1.547-1.555. Inokuncibilika okubalulekile kwamafutha futhi incibilika kalula kuzincibilikisi zemvelo njenge-ethanol ne-ether, kodwa inokuncibilika okungekuhle emanzini, futhi idinga ukufakwa nge-microencapsulated ukuze kuthuthukiswe ukuhlakazeka kwayo ekudleni.

 

Mayelana nokuzinza, i-vitamin A acetate izwela ukukhanya, ukushisa nomoya-mpilo, futhi idinga ukugcinwa kude nokukhanya (2-8 ° C), futhi ama-antioxidants afana ne-BHT ayengezwa ukuze kunwetshwe impilo yeshalofu. I-bioavailability yayo iphezulu ngokufinyelela ku-80% -90%, futhi iguqulwa ibe i-retinol nge-enzymatic hydrolysis emzimbeni futhi ibambe iqhaza ku-physiological metabolism.

 

● Yiziphi Izinzuzo ZazoI-Vitamin A Acetate?

1. Umbono kanye Nokulawulwa Kwamasosha omzimba

Njengendlela esebenzayo yevithamini A, ibamba iqhaza ekwakhiweni kombono ngokuguqula i-retinal, ivimbele ukungaboni ebusuku kanye nesifo samehlo esomile. Ngesikhathi esifanayo, ithuthukisa umsebenzi wokuvimbela amangqamuzana e-epithelial futhi inciphisa ingozi yezifo zokuphefumula. Izivivinyo zemitholampilo zibonise ukuthi zingathuthukisa ukuzivikela kwezingane ngama-30%.

 

2. Isikhumba Esilwa Nokuguga Nokulungisa

Ivimbela ukwanda ngokweqile kwama-keratinocyte, ikhuthaza ukwakheka kwe-collagen, futhi inciphisa ukujula kwemibimbi ngama-40%. Ukwengeza ukugxila okungu-0.1% -1% kuzimonyo kungathuthukisa ukuthwebula izithombe nezibazi zezinduna. Isibonelo, ukhilimu wochungechunge lwe-Lancome's Absolue usebenzisa lokhu njengesithako esiyinhloko sokulwa nokuguga.

 

3. I-Metabolism Nokwelashwa Kwe-Adjuvant Yezifo

Ilawula i-lipid metabolism futhi yehlise amazinga e-cholesterol. Ukuhlolwa kwezilwane kubonise ukuthi kungabambezela ukuqhubeka kwesifo sesibindi esinamafutha angenatshwala. Ngaphezu kwalokho, ekwelashweni kwe-adjuvant yomdlavuza, kukhombisa inani lesicelo elingaba khona ngokufaka i-tumor cell apoptosis.