I-Synephrine Hydrochloride: "Into Engokwemvelo Eyenyusa Umfutho Wegazi" Ekhishwe Ku-Citrus Aurantium

●Yini? I-Synephrine Hydrochloride?

I-Synephrine HCl iyindlela ye-hydrochloride ye-synephrine, enefomula yamakhemikhali C₉H₁₃NO₂·HCl (isisindo se-molecular 203.67). I-precursor yayo yemvelo ye-synephrine ikakhulukazi itholakala ezithelweni ezincane ezomisiwe (i-citrus aurantium) yesitshalo se-Rutaceae. I-Citrus aurantium isatshalaliswa kabanzi ezifundazweni zase-Yangtze River Basin zase-China, njenge-Sichuan, i-Jiangxi, ne-Zhejiang. Okuqukethwe kwe-synephrine ezithelo zayo ezincane kungafinyelela ku-30% wesisindo esomile. Ukukhishwa kwendabuko kuncike ekukhishweni kotshwala (75% ethanol reflux extraction izikhathi ezi-3, isivuno ≥ 85%), kodwa eminyakeni yamuva nje, ukusungulwa kwezobuchwepheshe kugxile ekusebenzeni kahle okuluhlaza nokusebenza okuphezulu:

Ukuhlukaniswa kwe-Enzymatic hydrolysis-membrane: i-compound pectinase hydrolyzes pectin ku-40 ° C ne-pH 4.5, kuhlanganiswe nokuhlunga kwe-ceramic membrane ye-ceramic engu-0.22μm, izinga lokususwa kokungcola lifinyelela ku-91%, futhi ubumsulwa bukhuphukela ngaphezu kwama-95%;

Ubuchwepheshe bokufaka esikhundleni sesikhunta: I-Chinese Academy of Agricultural Sciences ithuthukise indlela ye-Ganoderma lucidum fermentation ukukhiqiza izinto ezifana ne-synephrine, ukunciphisa izindleko ngo-30% futhi kunciphise ingcindezi yokumba izimayini ezingekho emthethweni zemithombo yasendle.

●ZiyiniIzinzuzoKwe I-Synephrine Hydrochloride ?

I-Synephrine hydrochloride, njenge-agonist ekabili ye-adrenaline α/β receptors, ilungisa kabusha inani lomtholampilo ngemiphumela eqondiwe kaningi:

1. Isimo esiphuthumayo senhliziyo

Ama-receptors ajabulisayo e-α ukuze abambe imithambo yegazi futhi akhulise umfutho wegazi, osetshenziselwa i-anesthesia, i-hypotension, ukuhlenga ukushaqeka, kanye nesivinini sokuqala singu-40% ngokushesha kunezidakamizwa zendabuko;

Ukwenza kusebenze ama-β receptors ukuthuthukisa ukufinyela kwe-myocardial futhi kuthuthukise umsebenzi wokupompa weziguli ezinokwehluleka kwenhliziyo.

2. Ukungenelela Kwesistimu Yokuphefumula

I-Synephrinehi-hydrochloridekungaba sivule kakhulu imisipha ebushelelezi ye-bronchial, iphikisane ngokuphelele ne-spasm ebangelwa i-histamine, futhi ikhulise inkomba ye-FEV1 yokusebenza kwamaphaphu ezigulini ezinesifuba somoya we-bronchial ngama-25%.

3. Ukulawulwa kweMetabolic

Ukuguquguquka kwe-oxidation yamafutha: Khuthaza izinga lokuguquguquka kwezicubu ze-adipose ezinsundu ngo-50%, futhi ukudla kwansuku zonke kwe-20 mg kunganciphisa izinga lamafutha omzimba ngo-3.5%;

Amandla e-Neuroprotective: Vimbela ngokubuyisela i-acetylcholinesterase, thuthukisa ukusebenza kwengqondo kweziguli eziwohlokayo ngo-30%, futhi ubude besikhathi sokusebenza buphindwe kabili kunezidakamizwa ezivamile.

Ukutholwa kwemingcele: Ucwaningo lwango-2020 olwenziwa iSouthwest University lwembula ngokokuqala ngqa umsebenzi walo wokulondoloza izithelo nemifino - 0.1mmol/Li-synephrine hydrochlorideUkwelashwa kungavimbela umsebenzi we-polyphenol oxidase ecwecweni le-litchi, kubambezele ukunsundu ngokulawula ulwelwesi lwe-lipid metabolism, futhi kwandise impilo yeshalofu ibe yizinsuku eziyi-14.

●ZiyiniIsiceloOf I-Synephrine Hydrochloride?

1. Imakethe Ebusayo Ensimini Yezemithi

Amalungiselelo osizo lokuqala: imijovo namaphilisi asetshenziselwa ukuhlinzwa kwe-hypotension kanye nokushaqeka.

Ukulawulwa kwezifo Ezingamahlalakhona: kuhlanganiswe ne-aminophylline ukwelapha isifuba somoya, izinga lokuhlasela elinamandla lehla ngo-60%.

Izidakamizwa zokunciphisa umzimba: njengengxenye yemvelo ye-ephedrine, ingasetshenziswa njengesengezo sezemidlalo.

2. I-Agricultural Preservation Innovation

I-Lychee browning inhibitor: ngemuva kokuthi i-lychee ivunwe futhi iphathwe ngayoi-synephrine hydrochloride, izindleko eziphelele ziyi-1/3 kuphela yeketanga elivamile elibandayo.

I-Citrus Antiseptic Coating: I-nanoemulsion ehlanganiswe ne-chitosan, izinga lokulwa namagciwane li> 99%, futhi isikhathi sokugcina ekamelweni lokushisa sinwetshwa ngezinsuku ezingu-21.

3. Ukunwetshwa Kwemikhiqizo Esebenzayo Yabathengi

Iziphuzo zamandla: "Synephrine + taurine" iziphuzo ezisebenzayo zingathuthukisa ukukhuthazela kwezemidlalo

Ukudla kwezempilo kwe-Neural: amalungiselelo e-capsule aqondise i-acetylcholinesterase ukuthuthukisa ukukhubazeka kwenkumbulo kubantu asebekhulile.

● Newgreen Supply High Quality I-Synephrine Hydrochloride Impushana