●Yini? I-Sodium 3-Hydroxybutyrate ?
I-sodium 3-hydroxybutyrate (i-sodium β-hydroxybutyrate, i-BHB-Na) iyinto eyinhloko ye-ketone body metabolism. Ikhona ngokwemvelo egazini nasemchamweni, ikakhulukazi esimweni sendlala noma i-carbohydrate ephansi. Ukulungiswa kwendabuko kusekelwe ku-hydrolysis ye-3-hydroxybutyric acid esters (i-methyl ester/ethyl ester) ne-sodium hydroxide, kodwa idinga i-organic solvent recrystallization, okuholela enkambisweni eyinkimbinkimbi, ukumuncwa umswakama kalula kanye nokuhlanganiswa kwemikhiqizo, kanye nezincibilikisi ezisele zingathinta ukuphepha kwezicelo zezokwelapha.
Njengamanje, ezinye izinkampani zenze ukuthuthukiswa kwenqubo emisha: ukungcola kwe-crotonic acid kulawulwa ngaphansi kwe-16ppm nge-methanol-acetone fractional crystallization method, futhi ubumsulwa bukhuphukela ku-99.5%, obuhlangabezana nezinga lomjovo;
Ubuchwepheshe be-crystallization besinyathelo esisodwa sokomisa isifutho busebenzisa umoya oshisayo ongu-160 ℃ ukuguqula ngokuqondile uketshezi olusabelayo lube amakristalu ayindilinga, ngesivuno somkhiqizo esingaphezu kuka-95%. I-X-ray diffraction spectrum ibonisa iziqongo zesici ezingu-17 (2θ = 6.1 °, 26.0 °, njll.), futhi ukuzinza kwesakhiwo sekristalu kuphakeme izikhathi ezingu-3 kunenqubo yendabuko, exazulula ngokuphelele inkinga yokumuncwa umswakama.
●ZiyiniIzinzuzoKwe I-Sodium 3-Hydroxybutyrate ?
Njenge- “super fuel molecule”, i-sodium 3-hydroxybutyrate ihlinzeka ngokuqondile amandla ngokusebenzisa umgoqo wegazi nobuchopho, futhi indlela yayo yokuphila iye yahlolisiswa ngokujulile eminyakeni yamuva nje:
Ukulawulwa kweMetabolic:Kumodeli yesifo sikashukela, kuthuthukisa ukuzwela kwe-insulin. Umthamo owodwa (0.2 mg/kg) ungakhuphula izinga le-glycogen synthesis yesibindi ngo-40%;
I-Neuroprotection:Ucwaningo luye lwathola ukuthi i-3-hydroxybutyrate methyl ester ephuma kuyo ingakwazi ukusebenzisa iziteshi ze-calcium zohlobo lwe-L, ikhulise ukuhlushwa kwe-calcium ion kumaseli e-glial ngo-50%, futhi ivimbele i-apoptosis yamaseli ngo-35%, inikeze indlela entsha yokwelashwa kwesifo i-Alzheimer's;
I-Anti-Inflammatory kanye ne-Antioxidant:Ngokunciphisa i-lipid peroxides kanye nezinhlobo ze-oxygen esebenzayo (i-ROS), ikhulula ukuvuvukala kwemisipha ngemva kokuzivocavoca, futhi ukusebenza kokukhuthazela kwabasubathi kuba ngcono ngo-22% ngemuva kokwengeza.
●ZiyiniIsiceloKweI-Sodium 3-Hydroxybutyrate ?
1. Imboni Yezempilo: I-Core Carrier Of Ketogenic Economy
Ukulawulwa kwesisindo: njengesithako esiyinhloko sezithako ze-ketogenic, ivuselela ukusebenza kahle kwe-ketogenic yesibindi.
Umsoco wezemidlalo: iziphuzo ze-electrolyteI-Sodium 3-Hydroxybutyratekuhlanganiswe nama-amino acid e-branched-chain angakwazi ukugcina ukugxila kwe-ketone yegazi ngaphezu kwe-4mM ngemva kokuzivocavoca futhi kufinyeze isikhathi sokululama kwemisipha ngo-30%.
2. Inkambu Yezokwelapha: Ithemba Elisha Lezifo Ze-Neurodeergenerative
Ukwelashwa kwe-adjuvant yesithuthwane: kuhlanganiswe nama-anticonvulsants kunganciphisa imvamisa yokuquleka ngo-30%, futhi izivivinyo zomtholampilo zesigaba sesi-III seziqalisiwe;
Isistimu yokulethwa okuqondisiwe: Ama-Cy7 fluorescent probes anelebuli etholakala ekulandeleleni i-vivo, kanye nesithombe esiseduze ne-infrared sibonisa ukuthi inothiswa ku-hippocampus phakathi namahora angu-2, ihlinzeka ngokuphathwa kwezidakamizwa zobuchopho.
3. Isayensi Yezinto Ezibalulekile: Ukhiye Webhayoloji Wokuqeda Ukungcola Okumhlophe
Amapulasitiki angaboli: Ahlanganiswe ne-polyester enamakha ukuze akhe i-PHB (i-poly 3-hydroxybutyrate), enephuzu lokuncibilika elingu-175°C kanye nokungena komoyampilo okungu-1/10 kuphela kwe-PET. Ingonakaliswa ngokuphelele enhlabathini ye-anaerobic ezinsukwini ezingama-60. I-Guangdong Yuanda New Materials Co., Ltd. izuze ukukhiqizwa kwenani elikhulu lezimboni;
Ifilimu yezolimo ehlakazekayo: I-PE mulch ene-5% ye-sodium 3-hydroxybutyrate engeziwe, elahlekelwa izakhiwo zayo zomshini ngokuzenzakalelayo ngemva kokusetshenziswa, futhi ayinazo izinsalela ze-microplastic ngemva kokwenza umquba.
●NEWGREEN Supply High QualityI-Sodium 3-Hydroxybutyrate Impushana
Isikhathi sokuthumela: Jul-17-2025
