I-Polygonum Multiflorum Extract: Umphumela Womlingo Wokuphendula Izinwele Ezimhlophe Zimnyama

●Yini? I-Polygonum Multiflorum Extract?

I-Polygonum multiflorum iyisihlahla somvini esihlangene somndeni wakwaPolygonaceae. Izimpande zawo ze-epidermis zibomvu ngokubomvu kuya kunsundu ngokumnyama, futhi ingxenye ephambanayo imbozwe ngokuminyene ngezixha zemithambo eziyindilinga. Ikhiqizwa ikakhulukazi ezindaweni ezinezintaba zoMfula iYangtze eShaanxi, Gansu, Yunnan nakwezinye izindawo eChina. Ukumba kwendabuko kufanele kwenziwe ehlobo nasekwindla ukuze kugcinwe izithako ezisebenzayo. Isizinda sesimanje sisebenzisa ubuchwepheshe be-ethanol reflux obungama-70%. Ngemuva kokukhishwa okuthathu, kuyagxiliswa futhi kufuthwe ukuze kutholwe impushana ensundu-ophuzi, lapho isithako esisebenzayo se-stilbene glycoside singafinyelela ku-8% -95% (indlela ye-HPLC).

Phakathi kwama-metabolites ayi-1,186Ukukhishwa kwe-polygonum multiflorum, izigaba ezintathu ezinkulu zezingxenye zibonise ukusebenza kahle:

1. I-Stilbene glycosides: i-2,3,5,4′-tetrahydroxystilbene glycoside, i-neuroprotection, ukuvimbela ubuthi be-β-amyloid protein, kanye nokwenza ngcono ukufunda nekhono lenkumbulo lamagundane ayimodeli ye-Alzheimer ngo-40%

2. Okuphuma ku-anthraquinone: i-emodin, i-chrysophanol, ne-rhein, enemiphumela yokulwa namagciwane kanye nezinga lokuvinjelwa elingaphezu kuka-90% ku-Staphylococcus aureus; bangaphinda banciphise i-lipids futhi bavimbe ama-enzyme abalulekile ekuhlanganiseni kwe-cholesterol.

3. I-Lecithin: I-Phosphatidylcholine, ilungisa ulwelwesi lwamangqamuzana esibindi esinamafutha; anti-ukuguga, ithuthukisa ikhono lokulungisa i-lymphocyte 3DNA.

Ukutholwa okubalulekile: Ukuhlolwa kwenyuvesi kuqinisekisile ukuthi i-stilbene glycoside (100mg/kg) inganciphisa i-MDA (lipid peroxide) kuzicubu zobuchopho zamagundane aguga ngo-50% futhi yandise umsebenzi we-SOD ngezikhathi ze-2, kodwa okwedlula i-300mg/kg kuzodala ukungavamile kwe-transaminase.

● Ziyini IIzinzuzoKwe I-Polygonum Multiflorum Extract ?

1. Impilo Yesikhumba Ekhanda

Anti-izinwele ukulahlekelwa, izinwele ezimnyama: stilbene glycoside kusebenze tyrosinase umsebenzi wezinwele follicle melanocyte.

Isithiyo sokuguga: I-Lecithin ilungisa i-scalp stratum corneum, yehlisa ukukhiqizwa kwe-lipid peroxides, futhi yenza imikhiqizo yokunakekelwa kwezinwele ibe nemiphumela eyengeziwe yokulwa nokuguga.

2. Ukungenelela Kwezifo Ze-Neurodegenerative

Ukususwa okuhlosiwe kwephrotheni ye-β-amyloid: i-stilbene glycoside ivimba ukubopha kwayo kuma-neurons, inciphisa izinga le-apoptosis yeseli ngama-35%;

Lawula izakhi zofuzo ze-apoptosis: Phakamisa isisho se-Bcl-2, vimbela indlela ye-Caspase-3, futhi ulibazise ukuguga kwe-cerebral cortex.

3. I-Metabolic Syndrome Regulation

Ukuncishiswa kwe-Lipid: I-Polygonum multiflorum alcohol ekhishwe elungiselelwe (0.84g/kg) yehlisa i-quail plasma triglycerides ngo-40% phakathi kwamaviki angu-6;

Ukuvikelwa kwenhliziyo: Yehlisa ukulimala kwe-myocardial ischemia-reperfusion ngokuvula i-enzyme ye-SOD.

●ZiyiniFaka isicelo

Izimonyo ezilwa nokuguga: Inganezelwa ku-essence njengesicuphi se-SOD, futhi ukusebenza kahle kwayo ekuvimbeleni i-lipid peroxidation yesikhumba izikhathi ezi-3 kune-VE evamile.

Ukudla okusebenzayo: I-Polygonum multiflorum + γ-aminobutyric acid compound capsules, enenani elisebenzayo lama-80% ekuthuthukiseni ukuqwasha kokuya esikhathini.

● Izincomo zokukhipha i-Polygonum multiflorum:

Ezomlomo

Ukulawulwa kwemithamo: Ukudla okunconyiwe kwansuku zonke kufanele kulungiswe ngokomthethosisekelo ngamunye, ngokuvamile kungabi ngaphezu kwezikhathi ezi-3/ngesonto, ukugwema ukulimala kwesibindi ngokweqile. .

Isikhathi sokusebenzisa: Kungcono ukuthatha ngemuva kokudla ukugwema ukucasula umgudu wamathumbu esiswini esingenalutho. .

Izincomo zokuhambisana: Ingenziwa nge-wolfberry yaseShayina, izinsuku ezibomvu, i-angelica nezinye izinto zokwelapha ukuze kuthuthukiswe umphumela we-tonic. .

Ukusetshenziswa kwangaphandle

Ukunakekelwa kwesikhumba: I-antioxidant ne-anti-inflammatory properties ye-extract ingasetshenziswa ukulungisa umonakalo wesikhumba, kodwa ukuhlolwa okuncane kuyadingeka kuqala ukuze kugwenywe ukungezwani komzimba. .

Izinyathelo zokuqapha: Akuvunyelwe ukusetshenziswa esikhumbeni esinezilonda noma esibucayi, futhi ugweme ukuthintana ngqo.

●Ikhwalithi ephezulu ye-Newgreen Supply I-Polygonum Multiflorum ExtractImpushana