●Yini? I-Minoxidil?
Endabeni yengozi yomlando wezokwelapha, i-minoxidil ingabhekwa njengenye "yezinto ezitholwe ngengozi" eziphumelela kakhulu. Lapho isungulwa njengesidakamizwa esilwa nomfutho wegazi ophakeme ngeminyaka yawo-1960, umphumela oseceleni we-hypertrichosis owadalwa yikho waba inguquko ekwelapheni ukuqothuka kwezinwele. Ngemuva kweminyaka ecishe ibe ngu-60 yokuthuthuka, le nhlanganisela ithole amafomu amaningi omthamo njengezixazululo, amagwebu, namajeli. Isamba sezinga elisebenzayo le-5% le-minoxidil ekwelapheni i-telogen effluvium lidlula ama-80%, eliphinde liqinisekise amandla ayo okubonisa ukuphambana.
Igama lekhemikhali le-minoxidil yi-6-(1-piperidinyl) -2,4-pyrimidinediamine-3-oxide, enefomula yemolekyuli ye-C₉H₁₅N₅O, iphoyinti lokuncibilika elingu-272-274℃, iphoyinti elibilayo elingu-351.7℃, i-1.16³ ye-soluble indlwana engu-1.1cm, i-soluble indlwana engu-1. futhi incibilika kalula ku-ethanol ne-propylene glycol.
●ZiyiniIzinzuzoKwe I-Minoxidil ?
Ngokusekelwe ocwaningweni lwemishini yamangqamuzana, i-minoxidil ibonisa imiphumela yebhayoloji enezinhlangothi eziningi:
1. I-Vascular Dynamics
Yenza kusebenze iziteshi ze-potassium ezizwela ku-ATP (KATP), iphumuza imisipha ebushelelezi yemithambo, futhi ikhuphule ukugeleza kwegazi ekhanda ngama-40% -60%.
Ikhuthaza ukubonakaliswa kwe-VEGF, ikhuphule ukuminyana kwemithambo yegazi emisha izikhathi ezingu-2.3, futhi ithuthukise ukuhlinzekwa kwezakhi zama-follicle ezinwele.
2. Ukulawulwa Kwe-Hair Follicle Cycle
Nciphisa isigaba sokuphumula (kusuka ezinsukwini eziyi-100 kuye ezinsukwini ezingama-40) futhi andise isigaba sokukhula sibe ngaphezu kwezinsuku ezingama-200.
I-Minoxidilingenza kusebenze indlela ye-Wnt/β-catenin, futhi inyuse izinga lokusabalala kwamaseli e-hair papilla ngo-75%.
3. Ukuthuthukiswa Kwemvelo Encane Yasendaweni
Ivimbela umsebenzi we-5α-reductase, inciphisa ukugxila kwe-DHT ngo-38%, futhi ikhulule i-alopecia ye-androgenic.
Ilawula izici ezivuvukalayo ezifana ne-IL-6 ne-TNF-α, futhi inciphisa amaphuzu okuvuvukala kwesikhumba ngo-52%.
●ZiyiniIsiceloOf I-Minoxidil?
I-Minoxidil yeqa imingcele yezinkomba zendabuko:
1. Umuthi Wezinwele
I-Androgenetic alopecia: Isixazululo esingu-5% siphatha i-AGA yabesilisa, futhi izinga lokumbozwa kwezinwele likhuphuka ngo-47% ezinyangeni eziyi-12.
I-Alopecia areata: Ucwaningo lwase-Japan ngo-2025 lwabonisa ukuthi ukusebenza kahle kwama-JAK inhibitors ahlanganisiwe kwenyuke kusuka ku-35% kuya ku-68% ngomuthi owodwa.
2. Ukuvuselelwa Kwesikhumba
Izilonda ezinyaweni zesifo sikashukela: Ukusetshenziswa kwendawo kusheshisa ukuphulukiswa kwesilonda futhi kufinyeze isikhathi sokuphola ngama-30%.
Ukulungisa isibazi: Kuvimbela isisho se-TGF-β1 futhi kunciphisa ubulukhuni besibazi ngo-42%.
3. Ezolimo kanye nokuvikelwa kwemvelo
Umthetho wokukhula kwezitshalo: Isixazululo esingu-0.1ppm siphatha irayisi, futhi inani lamathila likhuphuka ngo-18%.
Ukulungiswa komhlabathi: Ukusebenza kahle kwe-adsorption ye-heavy metal cadmium kufinyelela ku-89%, esetshenziselwa ukubuyisela imvelo ezindaweni zezimayini.
●Izinyathelo zokuphephakweI-Minoxidil Ukusetshenziswa Kwesikhathi Eside
Izinkomba zokuqapha: Hlola njalo umfutho wegazi nokushaya kwenhliziyo, ikakhulukazi kulabo abanezifo zenhliziyo nemithambo yegazi;
Amaqembu aphikisanayo: Abesifazane abakhulelwe, abancelisayo, nalabo abangezwani ne-propylene glycol banqatshelwe;
Ukukhethwa kwefomu lomthamo: 5% ukugxila kunconywa amadoda, futhi 2% ingakhethwa kwabesifazane ukunciphisa side effects;
Ukwelashwa okuhlanganisiwe: Ukulahlekelwa izinwele kakhulu kungahlanganiswa ne-finasteride (yamadoda) noma ukwelapha nge-laser ene-low-energy.
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●Newgreen Supply High Quality I-MinoxidilImpushana
Isikhathi sokuthumela: Aug-20-2025
