I-Enterococcus Faecium: Izicelo Ezihlukahlukene Ekudleni, Okuphakelayo, Nokuningi

●Yini? I-Enterococcus Faecium?

I-Enterococcus Faecium, ilungu elihlala esitshalweni samathumbu omuntu nesilwane, sekuyisikhathi eside isebenza ocwaningweni lwamagciwane njenge-pathogen engosomathuba kanye ne-probiotic. Izici zayo eziyingqayizivele zesayensi yemvelo kanye nokwehlukahlukana kokusebenza kunikeza ithuba elibanzi lokusetshenziswa kwezolimo, ukunakekelwa kwezempilo, nokuphathwa kwemvelo, kodwa ubungozi obuhambisanayo bokumelana nezidakamizwa budonse ukunakwa okubalulekile kwesayensi.

I-Enterococcus Faecium i-Gram-positive, i-hydrogen peroxide-negative coccus enobubanzi obungu-0.5-1.0 microns. Intula izinhlamvu kanye ne-capsule futhi ingakha amaketanga amafushane noma amakholoni owodwa. Njengenhlobo emele yohlobo lwe-Enterococcus, isatshalaliswa kabanzi emapheshaneni okugaya nokuzala abantu nezilwane ezincelisayo, kanye nasendaweni ezungezile, yakha ubudlelwano be-symbiotic nomsingathi wayo. Kodwa-ke, ezinye izinhlobo zithwala izakhi zofuzo ze-virulence (njengama-hemolysins nama-adhesin) angabangela ukutheleleka, okwenza kube yi-pathogen ebalulekile yezifo ze-nosocomial.

●ZiyiniIzinzuzoKwe I-Enterococcus Faecium ?

1. Umsebenzi we-Prebiotic

Ukwakhiwa Kwezithiyo: Namathela ku-epithelium yamathumbu ukuze wenze i-biofilm, uvimbele ukoloni we-Escherichia coli ne-Salmonella, futhi unciphise amazinga ezici zokuvuvukala kwamathumbu.

I-Immunomodulation: Yenza kusebenze ama-macrophage, ukhuthaze ukukhiqizwa kwe-antibody, futhi uthuthukise ukumelana nezifo.

I-Nutrient Metabolism: Hlukanisa amaprotheni abe ama-peptide amancane, ahlanganise amavithamini B, futhi akhuthaze ukumuncwa kwe-calcium.

2. I-Pathogenic Mechanism

I-Host Protein Hijacking: Ibophezela kumsingathi i-FABP2 protein nge-surface receptor EF3041, ivule indlela yokuzwa ikhoramu futhi ibhebhethekise i-dysbiosis yamathumbu ku-Crohn's disease.

Ukuvezwa Okuyingozi: Kubantu abasengozini yokuzivikela komzimba, igciwane lingena egazini, umchamo, nezinye izitho zomzimba, libangele i-endocarditis, izifo ze-urinary tract, namathumba angemva kokuhlinzwa.

●ZiyiniIsiceloOf I-Enterococcus Faecium?

1. Ukufuya Izilwane

Isengezo Sokuphakelayo: Engeza amagremu angu-100-200 ngethani ukuze uthuthukise i-microbiome yamathumbu, unciphise izinga lohudo, futhi unciphise ukukhishwa kwe-ammonia nitrogen.

I-Silage Fermentation: Isebenza ngokuhambisana ne-cellulase ukuze kuthuthukiswe ukunambitheka kwesiphakeli kanye nenani lokudla okunempilo.

2. Ukulima kwezilwane zasemanzini

Ukuhlanzwa kwamanzi: Faka amagremu angama-50-100 ngemu ngayinyei-enterococcus faeciumukwehlisa i-ammonia nitrogen ne-nitrite, ukuvimbela ukuqhakaza kwe-algae eluhlaza okwesibhakabhaka.

Ukulawula Izifo: Ivimbela amagciwane asemanzini ngokukhipha ama-peptide e-antimicrobial, ukunciphisa ukuthembela kwama-antibiotic.

3. Ezokwelapha

Amalungiselelo E-Probiotic: Asetshenziswa kuma-suppositories e-vagin noma amalungiselelo omlomo ukuze alawule ibhalansi yebhaktheriya (Qaphela: Ngenxa yengozi yokumelana nemithi, amanye amazwe akhawulela ukusetshenziswa kwawo kwezokwelapha).

Ucwaningo Lokumelana Nezidakamizwa: Isetshenziswa njengemodeli yebhaktheriya ukuhlaziya izindlela zokudlulisela zokumelana nama-antibiotic.

●Umthamo kanye Nemihlahlandlela YokuphephakweI-Enterococcus Faecium

1. Umthamo onconyiwe

Ukudla Kwemfuyo Nezinkukhu: 150 g/ton ngesikhathi sokukhuluphalisa, 200-250 g/ton ngesikhathi sokulunyulwa, izinsuku eziyi-10-15.

I-Aquaculture: 0.5 g/m2 yokwelashwa kwemvelo, phinda njalo ezinsukwini ezingu-5-7 ezindaweni eziwohloke kakhulu.

2. Izinyathelo zokuqapha

Gwema ukuxubana nezibulala-magciwane noma amanzi ashisayo. Gcina endaweni epholile, eyomile.

Izicelo zezokwelapha zidinga ukuhlolwa okuqinile kokumelana nomuthi. Ukuhlanganiswa nezidakamizwa ezifana ne-vancomycin akuvunyelwe.

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●Ikhwalithi ephezulu ye-Newgreen Supply I-Enterococcus FaeciumImpushana