●Yini I-Caffeic Acid?
I-Caffeic acid, igama lamakhemikhali i-3,4-dihydroxycinnamic acid (ifomula ye-molecular C₉H₈O₄, CAS No. 331-39-5), iyinhlanganisela yemvelo ye-phenolic acid etholakala kabanzi ezitshalweni. Ibukeka njengekristalu ephuzi, inyibilika kancane emanzini abandayo, incibilika kalula emanzini ashisayo, i-ethanol ne-ethyl acetate, inephuzu lokuncibilika elingu-194-213 ℃ (izinqubo ezihlukene ziyahlukahluka), isixazululo esisawolintshi-bomvu kusixazululo se-alkaline, nombala oluhlaza okotshani uma uthintana ne-ferric chloride.
Imithombo eyinhloko yokukhipha ihlanganisa:
●Izitshalo zokwelapha:I-Asteraceae Solidago, isinamoni, i-dandelion (equkethe i-caffeic acid ≥ 0.02%), i-Ranunculaceae Cimicifuga rhizome;
●Izinsiza zezithelo nemifino:ikhasi lemon, amajikijolo, i-apula, i-broccoli nemifino ye-cruciferous;
●Izithako zesiphuzo:ubhontshisi wekhofi (ngesimo se-chlorogenic acid esters), iwayini (ehlanganiswe ne-tartaric acid).
Ubuchwepheshe besimanje busebenzisa isizinda se-CO₂ esibucayi kakhulu noma ubuchwepheshe be-bio-enzymatic hydrolysis ukuhlanza i-caffeic acid ezintweni ezingavuthiwe zezitshalo, ngobumsulwa obungaphezu kuka-98%, obuhlangabezana nezindinganiso zebanga lezemithi nezimonyo.
● Yiziphi Izinzuzo Zazo I-Caffeic Acid?
I-Caffeic acid ibonisa imisebenzi eminingi yezinto eziphilayo ngenxa yesakhiwo sayo se-o-diphenolic hydroxyl:
1. I-Antioxidant Kanye Ne-Anti-Inflammatory:
Inamandla amakhulu okukhukhula ama-radical mahhala phakathi kwe-hydrogenated cinnamic acid, futhi ukusebenza kahle kwayo kuphindwe izikhathi ezi-4 kune-vitamin E. Ivimbela ukusabela kweketango le-lipid peroxidation ngokwenza izakhiwo zequinone;
Ivimbela i-leukotriene synthesis (ilawula ukuzivikela komzimba nokuvuvukala), inciphisa ukulimala kwe-DNA yesikhumba ebangelwa yi-UV, futhi inciphisa inkomba ye-erythema ngo-50%.
2. Ukuvikelwa Kwe-Metabolic Nenhliziyo:
I-Caffeic acidIvimbela i-low density lipoprotein (LDL) oxidation futhi inciphise ukwakheka kwama-atherosclerotic plaque;
Ekuhlolweni kwegundane lokudla okunamafutha aphezulu, ukuqoqwa kwamafutha e-visceral kwehle ngo-30% kanye ne-triglycerides yesibindi yehle ngo-40%.
3. I-Neuroprotection kanye ne-Anti-Tumor:
Ukubonakaliswa kwe-insulin ye-hippocampal okuthuthukisiwe, umsebenzi wenkumbulo othuthukisiwe kumamodeli wesifo i-Alzheimer's, kanye nokunciphisa ukufakwa kwamaprotheni e-β-amyloid;
Ivimbela ukwanda kwamaseli omdlavuza we-fibrosarcoma futhi ivimbele ukukhula kwesimila ngokunciphisa i-DNA methylation.
4. I-Hemostasis kanye Nokwanda Kwe-Leukocyte:
Inciphisa ama-microvessels futhi ithuthukise umsebenzi we-coagulation factor. Isetshenziselwa ukwelapha i-hemostasis yokuhlinzwa kanye ne-leukopenia ngemva kokwelashwa ngamakhemikhali, ngenani elisebenzayo elingaphezu kwama-85%.
● Yiziphi Izicelo Ze I-Caffeic Acid ?
Ukusetshenziswa kwe-caffeic acid kuhlanganisa imikhakha eminingi:
1. Umuthi:amaphilisi e-caffeic acid (i-hemostasis, ukwanda kwamangqamuzana egazi amhlophe), izidakamizwa ezihloselwe ukulwa nesimila (isivivinyo somtholampilo sesigaba II se-succinic acid)
2. Izimonyo:i-sunscreen (i-synergistic zinc oxide ukwandisa inani le-SPF), i-essence emhlophe (inhibit tyrosinase, izinga lokuvinjelwa kwe-melanin 80%)
3. Imboni Yokudla:izilondolozi zemvelo (ukubambezela i-lipid oxidation yezinhlanzi), iziphuzo ezisebenzayo (anti-oxidation kanye ne-anti-inflammatory), ukusetshenziswa kwe-synergistic kwe-ascorbic acid
4. Ezolimo kanye nokuvikelwa kwemvelo:izibulala-zinambuzane zemvelo (zivimbela i-cotton bollworm protease), ukuguqulwa koboya (izakhiwo ze-antioxidant zikhuphuke ngo-75%)
●Imithetho Yokusebenzisa NokuphephaKweI-Caffeic Acid
Umthamo womuthi:Amaphilisi e-Caffeic acid: 0.1-0.3g kanye, izikhathi ezi-3 ngosuku, izinsuku ezingu-14 njengenkambo yokwelashwa, inani leplatelet lidinga ukugadwa (kwehliswe lapho> 100×10⁹/L, kudingeka uthintane nodokotela ngaphambi kokusetshenziswa);
Contraindications:I-contraindicated kwabesifazane abakhulelwe kanye neziguli ezine-hypercoagulable state; esetshenziswa ngokuqapha ezigulini ezinokukhubazeka kwesibindi kanye nezilonda zesisu.
Izithasiselo zezimonyo:U-0.5% -2% wengezwa emikhiqizweni emhlophe, encibilikiswe ngaphambili ku-ethanol bese yengezwa ku-matrix enamanzi ukuze kugwenywe ukuhlangana.
Izidingo zesitoreji:ivalwe endaweni emnyama, efrijini ku-2-8 ℃, isebenza iminyaka emi-2 (amalungiselelo oketshezi adinga ukuvikelwa ekungcolisweni nasekuwohlokeni)
●NEWGREEN SupplyI-Caffeic AcidImpushana
Isikhathi sokuthumela: Jul-23-2025
