I-Newgreen Ethengiswa Kakhulu I-S-adenosyl methionine 99% Yesengezo se-S-adenosyl methionine Powder Ngenani Elingcono Kakhulu
Incazelo Yomkhiqizo
I-S-Adenosyl Methionine (i-SAM noma i-SAMe) iyinhlanganisela ekhiqizwa ngokwemvelo emzimbeni, ikakhulukazi i-adenosine triphosphate (ATP) ne-methionine. I-SAMe idlala indima ebalulekile ekuphenduleni okuningi kwe-biochemical, ikakhulukazi ekuphenduleni kwe-methylation.
Izici Eziyinhloko
1. I-Methyl donor: I-SAMe ingumnikezeli we-methyl obalulekile futhi ibamba iqhaza ohlelweni lwe-methylation ye-DNA, i-RNA namaprotheni. Lokhu kusabela kwe-methylation kubalulekile ekuvezeni izakhi zofuzo, ukusayina kwamaseli kanye nokulawulwa kwe-metabolic.
2. Ukuhlanganiswa kwama-molecule e-bioactive: I-SAMe ihileleke ekuhlanganisweni kwezinhlobonhlobo zama-molecule e-bioactive, okuhlanganisa ama-neurotransmitters (afana ne-dopamine ne-norepinephrine) nama-phospholipids (njenge-phosphatidylcholine).
3. I-Antioxidant Effect: I-SAMe inezindawo zokulwa ne-antioxidant ezingasiza ukuvikela amangqamuzana emonakalweni obangelwa ukucindezeleka okwenziwe nge-oxidative.
Sengiphetha, i-S-adenosylmethionine iyi-biomolecule ebalulekile enemisebenzi eminingi yezinto eziphilayo kanye nezicelo zomtholampilo ezingase zibe khona, kodwa kufanele isetshenziswe ngokuqapha nangokuhambisana nezeluleko zochwepheshe.
I-COA
Isitifiketi Sokuhlaziya
| Izinto | Imininingwane | Imiphumela | |
| Ukubukeka | Impushana emhlophe ukuya kokumhlophe | Iyahambisana | |
| Iphunga | I-infrared | Ihambisana nobubanzi bereferensi | Iyahambisana |
| I-HPLC | Isikhathi sokugcina senani eliphakeme kakhulu sihambisana nesampula yesithenjwa | Iyahambisana | |
| Okuqukethwe kwamanzi(KF) | ≤ 3.0% | 1.12% | |
| Umlotha one-sulphate | ≤ 0.5% | Iyahambisana | |
| PH(5% isixazululo esinamanzi) | 1.0-2.0 | 1.2% | |
| I-S,S-Isomer(HPLC) | ≥ 75.0% | 82.16% | |
| I-SAM-e ION(HPLC) | 49.5% -54.7% | 52.0% | |
| I-P-Toluenesulfonic Acid | 21.0%-24.0% | 22.6% | |
| Okuqukethwe kweSulfate(SO4)(HPLC) | 23.5%-26.5% | 25.5% | |
| I-Assay (S-Adenosyl-L-methionine Disulfate Tosylate) | 95.0%-102% | 99.9% | |
| Izinto ezihlobene (HPLC) | |||
| S-ADENOSYL-L-HOMOCYSTEINE | ≤ 1.0% | 0.1% | |
| U-ADENINE | ≤ 1.0% | 0.2% | |
| I-METHYLTHIOADENOSINE | ≤ 1.5% | 0.1% | |
| I-ADENOSINE | ≤ 1.0% | 0.1% | |
| UKUNGCOLA KONKE | ≤3.5% | 0.8% | |
| Ukuminyana kwenqwaba | > 0.5g/ml | Iyahambisana | |
| Insimbi Enzima | <10ppm | Iyahambisana | |
| Pb | <3ppm | Iyahambisana | |
| As | <2ppm | Iyahambisana | |
| Cd | <1ppm | Iyahambisana | |
| Hg | <0.1ppm | Iyahambisana | |
| I-Microbiology | |||
| Inani Lepuleti Eliphelele | ≤ 1000cfu/g | <1000cfu/g | |
| Imvubelo & Isikhunta | ≤ 100cfu/g | <100cfu/g | |
| E.Coli. | Okubi | Okubi | |
| I-Salmonella | Okubi | Okubi | |
| Isiphetho
| Ihambisana ne-USP37 | ||
| Isitoreji | Gcina endaweni engu-2-8 ℃ hhayi iqhwa, gwema ukukhanya okunamandla nokushisa | ||
| Impilo yeshelufu | Iminyaka emi-2 lapho igcinwe kahle | ||
Umsebenzi
I-S-Adenosine Methionine (SAMe) iyinhlanganisela eyenzeka ngokwemvelo emzimbeni, ngokuyinhloko eyakhiwe i-adenosine ne-methionine. Idlala indima ebalulekile ezinqubweni eziningi zezinto eziphilayo. Nansi eminye yemisebenzi esemqoka ye-SAMe:
1. Umnikeli weMethyl:I-SAMe inikela nge-methyl ebalulekile futhi ibamba iqhaza ekuphenduleni kwe-methylation emzimbeni. Lokhu kusabela kubalulekile ekuguqulweni kwe-DNA, i-RNA namaprotheni, okuthinta ukubonakaliswa kofuzo nokusebenza kwamaseli.
2. Thuthukisa ukwenziwa kwe-neurotransmitter:I-SAMe isiza ukuhlanganisa ama-neurotransmitters ahlukahlukene ohlelweni lwezinzwa, njenge-serotonin ne-dopamine, ahlobene eduze nokulawulwa kwemizwelo kanye nempilo yengqondo.
3. Imiphumela Yokuqeda Ukucindezeleka:Ezinye izifundo zibonise ukuthi i-SAMe ingaba nomthelela omuhle ekucindezelekeni njengokwelashwa okuhambisanayo, okusiza ukuthuthukisa isimo sengqondo nokunciphisa izimpawu zokucindezeleka.
4. Impilo Yesibindi:I-SAMe idlala indima ebalulekile esibindini, ibamba iqhaza enqubweni yokukhipha ubuthi esibindini kanye ne-fat metabolism, isiza ukuvikela amangqamuzana esibindi futhi ikhuthaze impilo yesibindi.
5. Impilo Ehlangene:I-SAMe isetshenziselwa ukudambisa ukuvuvukala kwamalunga nobuhlungu, futhi ingase ithuthukise ukusebenza kwamalunga ngokukhuthaza ukuhlanganiswa nokulungiswa koqwanga.
6. Umphumela We-Antioxidant:I-SAMe inezici ezithile zokulwa ne-antioxidant ezisiza ukuvikela amaseli emonakalweni obangelwa ingcindezi ye-oxidative.
Sekukonke, i-S-adenosylmethionine idlala indima ebalulekile ezinhlobonhlobo zezinqubo zomzimba, ikakhulukazi empilweni yengqondo, ukusebenza kwesibindi, nempilo ehlangene. Nakuba ukusetshenziswa kwayo njengesithasiselo kuya kuvame kakhulu, kungcono ukubonana nodokotela noma uchwepheshe ngaphambi kokuyisebenzisa.
Isicelo
I-S-Adenosyl Methionine (SAMe) isetshenziswa kabanzi emikhakheni eminingi, ikakhulukazi kufaka phakathi izici ezilandelayo:
1. Ukucindezeleka nokuphazamiseka kwemizwelo
I-SAMe iye yacutshungulwa njengesithasiselo ukusiza ekwelapheni ukudangala. Ucwaningo luphakamisa ukuthi i-SAMe ingase ithuthukise isimo sengqondo ngokwandisa amazinga ama-neurotransmitters afana ne-dopamine ne-norepinephrine. Ezinye izivivinyo zomtholampilo zibonise ukuthi i-SAMe ingase isebenze njengemithi yendabuko edambisa ukucindezeleka ekudambiseni izimpawu zokucindezeleka.
2. Impilo Ehlangene
I-SAMe isetshenziselwa ukwelapha i-osteoarthritis nezinye izimo ezihlangene. Kungasiza iziguli ngokunciphisa ubuhlungu bamalunga kanye nokwenza ngcono umsebenzi. Olunye ucwaningo luphakamisa ukuthi i-SAMe isebenza ngendlela efanayo njengezidakamizwa ezingezona ukuvuvukala (ama-NSAID) ekudambiseni ukuvuvukala kwamalunga nobuhlungu, kodwa ibe nemiphumela engemihle embalwa.
3. Impilo Yesibindi
I-SAMe iphinde yakhombisa amandla ekwelapheni izifo zesibindi. Isetshenziselwa ukwelapha izifo ezifana ne-steatosis yesibindi, i-hepatitis, ne-cirrhosis. I-SAMe ingase isebenze ngokukhuthaza ukukhiqizwa kabusha kwamaseli esibindi nokuthuthukisa ukusebenza kwesibindi.
4. Impilo yesistimu yezinzwa
I-SAMe iphinde yathola ukunakwa ocwaningweni lwezifo ze-neurodeergenerative ezifana ne-Alzheimer's ne-Parkinson's. Ingase isekele impilo yesimiso sezinzwa ngokuthuthukisa ukuhlanganiswa kwama-neurotransmitters nokunciphisa ukucindezeleka okwenziwe nge-oxidative.
5. Impilo Yenhliziyo
Olunye ucwaningo luphakamisa ukuthi i-SAMe ingase izuze impilo yenhliziyo nemithambo yegazi, mhlawumbe ngokwehlisa amazinga e-homocysteine (i-homocysteine ephezulu ihlotshaniswa nobungozi besifo senhliziyo).
6. Ezinye izinhlelo zokusebenza
I-SAMe iphinde ifundelwe ezinye izindaba zezempilo, njenge-fibromyalgia, i-chronic fatigue syndrome, kanye nezinhlobo ezithile zomdlavuza. Nakuba ucwaningo mayelana nalezi zicelo lusaqhubeka, imiphumela yokuqala ibonisa isithembiso esithile.
Amanothi
Ngaphambi kokusebenzisa i-SAMe njengesithasiselo, kutuswa ukuthi ubonane nodokotela, ikakhulukazi kubantu abanezinkinga ezithile zempilo noma abaphuza eminye imithi. I-SAMe ingase ihlanganyele nemithi ethile, njengama-antidepressants, ngakho ukuqondisa kochwepheshe kubalulekile.
Sengiphetha, i-S-adenosylmethionine inezicelo ezingase zibe khona ezindaweni eziningi zezempilo, kodwa ucwaningo olwengeziwe luyadingeka ukuze kuqhutshekwe nokuqinisekisa ukusebenza kahle nokuphepha kwayo.
Iphakheji Nokulethwa
