●Kini Caffeic Acid?
Caffeic acid, orukọ kẹmika 3,4-dihydroxycinnamic acid (fomula molikula C₉H₈O₄, CAS No. 331-39-5), jẹ ẹya ara phenolic acid adayeba ti a rii ni awọn ohun ọgbin. O jẹ kirisita ofeefee ni irisi, tiotuka die-die ni omi tutu, ni irọrun tiotuka ninu omi gbona, ethanol ati ethyl acetate, pẹlu aaye yo ti 194-213 ℃ (awọn ilana oriṣiriṣi yatọ), osan-pupa ni ojutu ipilẹ, ati alawọ ewe dudu ni ifọwọkan pẹlu kiloraidi ferric.
Awọn orisun isediwon koko pẹlu:
●Awọn ohun ọgbin oogun:Asteraceae Solidago, eso igi gbigbẹ oloorun, dandelion (ti o ni caffeic acid ≥ 0.02%), Ranunculaceae Cimicifuga rhizome;
●Awọn orisun eso ati ẹfọ:lẹmọọn Peeli, blueberry, apple, broccoli ati cruciferous ẹfọ;
●Awọn eroja ohun mimu:awọn ewa kofi (ni irisi chlorogenic acid esters), ọti-waini (ti o ni idapọ pẹlu tartaric acid).
Imọ-ẹrọ ode oni nlo isediwon CO₂ supercritical tabi imọ-ẹrọ hydrolysis bio-enzymatic lati sọ caffeic acid di mimọ lati awọn ohun elo aise ọgbin, pẹlu mimọ ti o ju 98%, ni ipade awọn elegbogi ati awọn iṣedede ite ikunra.
● Kí Ni Àǹfààní Tiwa Caffeic Acid?
Caffeic acid ṣe afihan ọpọlọpọ awọn iṣẹ iṣe ti ibi nitori ọna o-diphenolic hydroxyl rẹ:
1. Antioxidant Ati Anti-iredodo:
O ni agbara scavenging radical ọfẹ ti o lagbara julọ laarin cinnamic acid hydrogenated, ati ṣiṣe rẹ jẹ awọn akoko 4 ti Vitamin E. O ṣe idiwọ awọn aati pq peroxidation lipid nipasẹ dida awọn ẹya quinone;
Idilọwọ awọn kolaginni leukotriene (ṣe ilana ajesara ati igbona), dinku ibajẹ DNA ti awọ ara ti UV, ati dinku atọka erythema nipasẹ 50%.
2. Metabolic Ati Idaabobo Ẹjẹ ọkan:
Kaffeic acidIdilọwọ awọn lipoprotein iwuwo-kekere (LDL) ifoyina ati dinku iṣelọpọ atherosclerotic plaque;
Ninu awọn idanwo asin ounjẹ ti o sanra, ikojọpọ ọra visceral dinku nipasẹ 30% ati awọn triglycerides ẹdọ dinku nipasẹ 40%.
3. Neuroprotection Ati Anti- tumo:
Ifilọlẹ hisulini hippocampal ti ilọsiwaju, ilọsiwaju iṣẹ iranti ni awọn awoṣe arun Alṣheimer, ati idinku amuaradagba β-amyloid;
Idilọwọ awọn afikun ti fibrosarcoma akàn ẹyin ati idilọwọ awọn tumo idagbasoke nipa atehinwa DNA methylation.
4. Hemostasis Ati Leukocyte Alekun:
O dinku awọn microvessels ati ilọsiwaju iṣẹ ti awọn ifosiwewe coagulation. O jẹ lilo ni ile-iwosan fun hemostasis abẹ ati leukopenia lẹhin chemotherapy, pẹlu iwọn to munadoko ti o ju 85%.
● Kini Awọn ohun elo ti Caffeic Acid ?
Ohun elo ti caffeic acid bo ọpọlọpọ awọn aaye:
1. Oogun:awọn tabulẹti caffeic acid (hemostasis, awọn sẹẹli ẹjẹ funfun ti o pọ si), awọn oogun ifọkansi ti tumo (succinic acid phase II idanwo ile-iwosan)
2. Ohun ikunra:iboju oorun (zinc oxide synergistic lati mu iye SPF pọ si), pataki funfun (dojuti tyrosinase, oṣuwọn idinamọ melanin 80%)
3. Ile-iṣẹ Ounjẹ:awọn olutọju adayeba (idaduro ifoyina ọra ẹja), awọn ohun mimu iṣẹ (egboogi-oxidation ati egboogi-iredodo), lilo amuṣiṣẹpọ ti ascorbic acid
4. Ogbin Ati Idaabobo Ayika:awọn ipakokoropaeku ilolupo (idinamọ protease bollworm owu), iyipada irun (awọn ohun-ini antioxidant pọ si nipasẹ 75%)
●Lilo Ati Awọn ilana AaboTiCaffeic Acid
Iwọn oogun:Awọn tabulẹti Caffeic acid: 0.1-0.3g lẹẹkan, awọn akoko 3 ni ọjọ kan, awọn ọjọ 14 gẹgẹbi itọju, iye platelet nilo lati ṣe abojuto (dinku nigbati> 100 × 10⁹ / L, nilo lati kan si dokita kan ṣaaju lilo);
Awọn itọkasi:Contraindicated fun awọn aboyun ati awọn alaisan ti o ni ipo hypercoagulable; ti a lo pẹlu iṣọra ni awọn alaisan ti o ni ailagbara ẹdọ ati ọgbẹ inu.
Awọn afikun ohun ikunra:0.5% -2% ti a fi kun si awọn ọja funfun, titu tẹlẹ ninu ethanol ati lẹhinna fi kun si matrix olomi lati yago fun agglomeration.
Awọn ibeere ipamọ:edidi ni aaye dudu, firiji ni 2-8 ℃, wulo fun ọdun 2 (awọn igbaradi omi nilo lati ni aabo lati ifoyina ati ibajẹ)
●NEWGREEN IpeseCaffeic AcidLulú
Akoko ifiweranṣẹ: Jul-23-2025
