I-oyile yeVithamin E : "Umgcini oZinzileyo" kwiNdawo ye-Anti-Oxidation

●Yintoni iVitamin E Oyile?

I-Vitamin E Oyile, igama lekhemikhali i-tocopherol, liqela leekhompawundi ezinyibilikayo ngamafutha (kubandakanyaα, β, γ, δ tocopherols), phakathi kwazoα-tocopherol inomsebenzi ophezulu webhayoloji.

Iimpawu eziphambili zeoyile yevithamini E zivela kwisakhiwo sayo esisodwa semolekyuli:

Ifomula yemolekyuli: C₂₉H₅₀O₂, equlethe i-benzodihydropyran ring kunye ne-hydrophobic side chain;

Iimpawu ezibonakalayo:

Imbonakalo: lulwelo oluluhlaza kancinci ukuya kumthubi okhanyayo, oluphantse lungabinavumba;

Ukunyibilika: akunyibiliki emanzini, ukunyibilika ngokulula kwizinyibilikisi eziphilayo ezifana ne-ethanol, i-ether, kunye ne-oyile yemifuno;

Uzinzo kunye novakalelo:

Ukumelana nobushushu obuphezulu (akukho kubola kwi-200℃), kodwa i-oxidized ngokukhawuleza kwaye iguqulwe xa ibonakaliswe ekukhanyeni, kunye neemveliso zokwenziwa zineempawu ezibuthathaka ze-antioxidant kuneemveliso zendalo;

Inovelwano emoyeni, kufuneka igcinwe kwindawo etywiniweyo nengenakukhanya (2-8℃).

Ulwazi oluncinci: Ivithamin E yendalo itsalwa ikakhulu kwioli yengqolowa, ioyile yesoya, kunye neoyile yombona, ngelixa iimveliso zokwenziwa ziveliswa ngobuninzi ngeendlela zemichiza, kodwa umsebenzi wazo webhayoloji yi-50% kuphela yeemveliso zendalo.

● Ziziphi iiNzuzo zeVitamin E Oyile ?

1. I-Antioxidant kunye ne-Anti-Aging Mechanism

IVithamin E yenye yezona antioxidants zinamandla ezinyibilikayo kumzimba womntu:

Ukukhupha i-radicals yamahhala: Ibamba i-radicals yamahhala ngokusebenzisa amaqela e-phenolic hydroxyl ukukhusela i-cell membrane lipids kumonakalo oxidative, kunye nokusebenza kwayo ngamaxesha e-4 ye-antioxidant eyenziwe (njenge-BHT);

I-Synergizing: Iyakwazi ukuvuselela i-vitamin E ene-oxidized xa isetyenziswe ngokudibanisa ne-vitamin C, kwaye iphucule ukusebenza kakuhle kwenethiwekhi ye-antioxidant.

2. Igalelo elingundoqo kwiMpilo yolusu

Ukulungiswa kwe-Photodamage: Yenza ifilimu ekhuselayo kwindawo yesikhumba, inciphisa i-UV-induced erythema kunye ne-DNA umonakalo, kwaye indawo ye-erythema iyancipha nge-31% -46% emva kokusetyenziswa kweklinikhi;

Ukufuma kunye nokuchasa ukuguga:vitamin e oyileikhuthaza i-ceramide synthesis, iphucula ukukwazi komqobo wesikhumba ukuvala ukufuma, kwaye iphucula ukoma kunye nemibimbi (ubunzulu bombimbi buncitshiswa ngama-40% emva kweenyanga ezi-6 zokusetyenziswa ngokuqhubekayo);

Ingxaki yokulungisa ulusu:

Ukuthintela umsebenzi we-tyrosinase, i-fade chloasma kunye neendawo zobudala;

Ukunciphisa i-seborrheic dermatitis kunye ne-angular cheilitis, kwaye ukhawuleze ukuphiliswa kwamanxeba okutsha.

3. Ungenelelo lweSifo seNkqubo

Impilo yokuzala: Ikhuthaza ukukhuselwa kwehomoni yesini, iphucula i-sperm motility kunye nomsebenzi we-ovarian, kwaye isetyenziselwa unyango oluncedisayo lokungazali kunye nokuphuphuma kwesisu okuphindaphindiweyo;

Ukukhuselwa kwesibindi: Izikhokelo zase-US zincoma njengokhetho lokuqala lwesifo sesibindi esinamafutha angenalo utywala, anokunciphisa i-transaminase kunye nokuphucula i-fibrosis yesibindi;

Ukukhusela kwi-cardiovascular: Ukulibazisa i-oxidation ye-low-density lipoprotein (LDL) kunye nokukhusela i-atherosclerosis;

Igazi kunye nokukhuseleka:

Ikhusela iiseli zegazi ezibomvu kwaye isetyenziselwa unyango lwe-antioxidant ye-thalassemia;

Ilawula impendulo yokuvuvukala kwezifo ezizimele (ezifana ne-lupus erythematosus).

●Yintoni IsicelosKwe Vitamin E Oyile ?

1. Indawo yezoNyango:

Amalungiselelo amiselweyo:

Iipilisi zomlomo: unyango lokukhupha isisu, ukuphazamiseka kwe-menopausal (i-dose yemihla ngemihla 100-800mg);

Izitofu: ezisetyenziselwa ityhefu ebukhali, ukhuseleko lwechemotherapy (kufuneka ifakwe ebumnyameni).

Amachiza amachiza: ama-creams aphucula ukuqhekeka kwesikhumba kunye ne-frostbite, kwaye isicelo sendawo sikhawuleza ukuphulukiswa kwesilonda46.

2. Izithambiso kunye noNonophelo lomntu:

I-essence yokuguga: yongeza i-0.5% -6%vitamin E ioli, i-asidi ye-hyaluronic edibeneyo yokuphucula ukuthambisa (isigaba seoli kufuneka sifakwe ngaphantsi kwe-80 ℃ xa silungiselela iikhrimu);

Ukwandiswa kwe-sunscreen: i-compound ne-zinc oxide ukwandisa ixabiso le-SPF kunye nokulungisa iiseli zeLangerhans ezonakaliswe yimitha ye-ultraviolet.

3. Ishishini lokutya:

I-nutrient enhancer: yongezwa ekudleni komntwana kunye neemveliso zempilo (ezifana nee-capsules ezithambileyo) ukuhlangabezana neemfuno zemihla ngemihla (i-dosage yemihla ngemihla yabantu abadala yi-15mg);

Izilondolozo zendalo: ezisetyenziselwa ioli kunye nokutya okunamafutha (okufana nekhilimu) ukulibazisa i-rancidity, kwaye ikhuselekile kune-BHA / BHT.

4. ezoLimo kunye nobuGcisa obusakhulayo

Izongezo zokutya: ukuphucula imfuyo kunye neenkukhu zokuzala kunye nomsebenzi wokuzala;

Ukuveliswa kwezinto ezintsha ezincedisa amayeza:

I-Vitamin E-TPGS (i-polyethylene glycol succinate): i-derivative e-soluble yamanzi, esetyenziswa njenge-solubilizer yokuphucula i-bioavailability yamachiza angenakunyibilika kakuhle;

Ifakwe kwi-nano-targeted drug (njengamalungiselelo achasene ne-tumor).

●UkusetyenziswaWi-arning of Vitamin E Oyile :

1. Ukhuseleko lwethamo:

Ukugqithisa kwexesha elide (> 400mg / ngosuku) kunokubangela intloko, isifo sohudo, kunye nokunyusa umngcipheko we-thrombosis;

Qaphela ukutshatyalaliswa kwe-anaphylactic ngexesha le-injection ye-intravenous (isilumkiso semiyalelo ehlaziyiweyo ye-China Food and Drug Administration kwi-2018).

2. Izilumkiso zosetyenziso lwaNgaphandle:

Isikhumba esithintekayo kufuneka sizanywe kwindawo encinci. Ukusetyenziswa okugqithisileyo kunokuvala iipores. Kunconywa ukusebenzisa amaxesha angama-1-2 ngeveki;

Izigulane ezine-chloasma kufuneka zisebenzise i-sunscreen (SPF≥50) ukunqanda ukwenzeka kwe-photosensitivity.

Abemi abakhethekileyo: Abasetyhini abakhulelweyo kunye nabasetyhini abancancisayo kufuneka bayisebenzise ngokwengcebiso kagqirha.

●Unikezelo ENTSHAVitamin E Oyile Umgubo