I-Vitamin A i-Acetate: Isithako esichasene nokuguga kwizongezo zeZondlo kunye neZithambiso

●Yintoni i Vitamin A Acetate?

I-Retinyl Acetate, i-chemical name retinol acetate, i-molecular formula C22H30O3, inombolo ye-CAS 127-47-9, i-derivative esterified derivative ye-vitamin A. Xa kuthelekiswa ne-vitamin A yotywala, iphucula ukuzinza nge-esterification reaction kwaye igweme ukubola kwe-oxidative, ibe yinto ebalulekileyo ekrwada kwiinkalo zeyeza kunye ne-cosmetics.

 

Ivithamin A yendalo ifumaneka ikakhulu kwisibindi sesilwanyana nasentlanzini, kodwa imveliso yemizi-mveliso isebenzisa i-chemical synthesis, efana nokusebenzisa i-β-ionone njenge-precursor kunye nokuyilungisa nge-Wittig condensation reaction. Kwiminyaka yakutshanje, iteknoloji yokulungiselela okuluhlaza njenge-ultrasound-enhanced interfacial enzyme catalysis iye yavela, iphucula kakhulu ukusebenza kakuhle kokuphendula kunye nokunciphisa ukungcola, ibe yikhokelo ephambili yokuphucula iteknoloji yoshishino.

 

Vitamin A acetatei-crystalline powder emhlophe ukuya ephuzi ekhanyayo okanye i-viscous liquid ene-melting point ye-57-58 ° C, indawo yokubilisa malunga ne-440.5 ° C, ubuninzi be-1.019 g / cm³, kunye ne-index refractive ye-1.547-1.555. Inonyibiliko olubalulekileyo lwamafutha kwaye lunyibilika ngokulula kwizinyibilikisi ze-organic ezifana ne-ethanol kunye ne-ether, kodwa inonyibiliko olubi lwamanzi, kwaye kufuneka ifakwe i-microencapsulated ukuphucula i-dispersibility yayo ekutyeni.

 

Ngokumalunga nokuzinza, i-vitamin A acetate inomdla ekukhanyeni, ukushisa kunye ne-oksijeni, kwaye kufuneka igcinwe kude nokukhanya (2-8 ° C), kunye ne-antioxidants ezifana ne-BHT zongezwa ukwandisa ubomi beshelufu. I-bioavailability yayo iphezulu njenge-80% -90%, kwaye iguqulwa ibe yi-retinol nge-enzymatic hydrolysis emzimbeni kwaye ithatha inxaxheba kwi-metabolism ye-physiological.

 

● Ziziphi iingeneloVitamin A Acetate?

1. Umbono kunye noLawulo lwamajoni omzimba

Njengoko ifom esebenzayo ye-vitamin A, ithatha inxaxheba ekubunjweni kombono ngokuguqula kwi-retinal, ukukhusela ukungaboni ebusuku kunye nesifo samehlo esomileyo. Kwangaxeshanye, iphucula umsebenzi womqobo weeseli ze-epithelial kwaye inciphisa umngcipheko wokosuleleka kokuphefumla. Ulingo lwezonyango lubonise ukuba lunokuphucula ukhuselo lomzimba lwabantwana ngama-30%.

 

2. Ulusu lokuchasa ukuguga kunye nokulungisa

Ivimbela ukwanda okugqithisileyo kwe-keratinocytes, ikhuthaza ukuhlanganiswa kwe-collagen, kwaye iyanciphisa ubunzulu bemibimbi ngama-40%. Ukongeza i-0.1% -1% ukugxininiswa kwizithambiso kunokuphucula i-photoaging kunye ne-acne scars. Umzekelo, i-Lancome's Absolue series cream isebenzisa oku njengesithako esichasene nokuguga.

 

3. I-Metabolism kunye noNyango lwe-Adjuvant yeSifo

Ilawula i-lipid metabolism kwaye yehlisa amanqanaba e-cholesterol. Uvavanyo lwezilwanyana lubonise ukuba lunokulibazisa ukuqhubela phambili kwesifo sesibindi esinamafutha angenatywala. Ukongeza, kunyango lwe-adjuvant yomhlaza, lubonisa ixabiso elinokubakho lesicelo ngokubangela i-apoptosis yeseli yethumba.