Ikhaphetshu emfusa iAnthocyanin: “Ukumkani weAnthocyanins” ongacingelwanga

●Yintoni i ikhaphetshu emfusa ianthocyanin ?

Ikhaphetshu emfusa (Brassica oleracea var. capitata f. rubra), ekwaziwa njengekhaphetshu emfusa, yaziwa ngokuba yi "king of anthocyanins" ngenxa yamagqabi ayo amfusa. Uphononongo lubonise ukuba yonke i-100 grams yekhaphetshu emfusa iqulethe i-90.5 ~ 322 mg ye-anthocyanins, ingaphezulu kakhulu kune-blueberries (malunga ne-163 mg / 100 grams), kwaye umxholo wamagqabi angaphandle uphezulu kakhulu kunamagqabi angaphakathi. Isithako saso esisebenzayo siphambili yi-cyanidin-3-O-glucoside (Cy-3-glucoside), ibalwa ngaphezu kwe-60%, incediswa ziintlobo ezi-5 zeekhompawundi ezifana ne-peony pigment derivatives, phakathi kwayo isakhiwo se-sinapinic acid peony pigment iyingqayizivele kwikhaphetshu emfusa.

 

Inkqubo yokukhutshwa kohlaza: Itekhnoloji ye-Supercritical CO₂ yokukhutshwa (ubunyulu ngaphezu kwe-98%) ithatha indawo yendlela yokunyibilikisa yemveli ukuphepha iintsalela zezinto eziphilayo;

 

Ukusebenza ngokomzimba kwe-UV-C: Uphando olwenziwa yi-Chinese Academy of Agricultural Sciences lufumene ukuba unyango olufutshane lwe-ultraviolet lunokubangela ukubonakaliswa kwekhaphetshu emfusa i-anthocyanin synthesis genes (MYB114, PAP1), ukwandisa umxholo ngaphezu kwe-20% kunye nokwandisa ubomi beshelufu;

 

Indlela ye-Microbial fermentation: Ukusebenzisa iintlobo zobunjineli ukuguqula i-glycosides ibe yi-aglycones esebenzayo, i-bioavailability yonyuka nge-50%

 

● Ziziphi iingenelo zeikhaphetshu emfusa ianthocyanin?

1. Impumelelo kwiNdlela yokuNqanda uMhlaza:

Umhlaza webele ongalunganga kathathu (TNBC):

I-Cy-3-glu ibophelela ngokukodwa kwi-TNBC i-membrane ye-membrane receptor ERα36, inqanda i-EGFR / AKT indlela yokubonisa, kwaye ikhuthaza i-apoptosis yeseli yomhlaza. Ulingo lwezonyango lubonise ukuba i-75% yezigulane ezingama-32 ze-TNBC zinembonakalo ephezulu ye-ERα36, kwaye izinga lokuthintela ithumba leempuku ezityiswe ngesicatshulwa sekhaphetshu elimfusa lidlula i-50%.

 

I-Melanoma:

Ngokuthintela ukulungiswa kwe-DNA ye-RAD51, iiseli zomhlaza zibanjwe kwisigaba se-G2 / M kwaye i-apoptosis ibangelwa.

 

2. I-Cardiovascular and Metabolic Protection

I-Antioxidant core: Ukusebenza kakuhle kwe-anthocyanins yeklabishi emfusa ekutshiseni i-radicals yamahhala ngamaxesha e-4 ye-vitamin E kunye ne-2.8 amaxesha e-vitamin C, ukunciphisa kakhulu izinga lokuvuvukala kwe-TNF-α;

 

Ukukhuselwa kweVascular: Ukuthathwa kwansuku zonke kwe-100 gramsikhaphetshu emfusa ianthocyanininokunciphisa i-cholesterol embi (i-LDL) kunye nokunciphisa ukubunjwa kwe-atherosclerotic plaques59;

 

Ukulawulwa kweswekile yegazi: I-Flavonoids (efana ne-quercetin) inqanda iziteshi zokufunxa i-glucose emathunjini kunye nokuphucula ukuvakalelwa kwe-insulin.

 

3. Impilo yamathumbu kunye neNkqubo yokuLwa nokudumba

Umthamo wefiber wesondlo uphindwe ka-2.6 kunekhaphetshu. Emva kokuvutshelwa, ivelisa i-butyrate (umthombo wamandla kwiiseli zekholoni), okwandisa ukuhlukahluka kwamathumbu emathunjini ngama-28% kunye nokunciphisa umngcipheko wokuphindaphinda kwe-ulcerative colitis;

 

I-Glucosinolates iguqulwa ibe yi-isothiocyanates, isebenze i-enzyme ye-detoxification yesibindi kunye nokususa i-carcinogens (njenge-metabolites yecuba).