IGarcinia Cambogia Extract Hydroxycitric Acid (HCA): Isithako sokuLahla kwaMafutha eNdalo

●YintoniI-Hydroxycitric Acid ?
IHydroxycitric Acid (HCA) yeyona nto isebenzayo kwi peel ye Garcinia cambogia. Ubume bayo beekhemikhali yi-C₆H₈O₈ (i-molecular weight 208.12). Ineqela elinye le-hydroxyl (-OH) kwindawo ye-C2 kune-citric acid eqhelekileyo, eyenza isakhono esisodwa sokulawula i-metabolic. I-Garcinia cambogia yinzalelwane yaseIndiya nakwi-mpuma ye-Asia. I-peel yayo eyomileyo kudala isetyenziswa njengesinongo sekhari, kwaye itekhnoloji yale mihla yokukhupha inokugxila kwi-10% -30% yeHCA kuyo. Ngo-2024, iteknoloji yaseChina enelungelo elilodwa lomenzi wechiza (CN104844447B) yandisa ubunyulu ukuya kwi-98% ngokusebenzisa i-low-hear high-shear extraction + inkqubo ye-nanofiltration desalination, ukusombulula ingxaki yeentsalela zokungcola kwi-asidi yendabuko ye-hydrolysis.

IiPropati zoMzi kunye nezeMichiza yeHydroxycitric Acid:
Imbonakalo: emhlophe ukuya kokukhanya kwekristale engumgubo otyheli, incasa emuncu kancinci;

I-Solubility: i-solubility ngokulula emanzini (> 50mg / mL), i-soluble kancinane kwi-ethanol, i-soluble kwi-solvents non-polar;

Ukuzinza: ukunyamezela ukukhanya nokushisa, kulula ukuhla xa i-pH <3, kufuneka igcinwe kude nokukhanya kunye nokushisa okuphantsi (<25℃);

Umgangatho wokufumanisa: ulwelo oluphezulu lwechromatography (HPLC) ukumisela umxholo, ukucoceka komgangatho ophezulu wesicatshulwa HCA kufuneka kube ≥60%.

●Ziziphi iiNzuzoI-Hydroxycitric Acid ?
I-HCA ifezekisa ukulahleka kwamafutha ngendlela ephindwe kathathu, kwaye ifaneleka ngakumbi kubantu abakwi-high-carb diet:

1. Inhibit Fat Synthesis
Ukhuphiswano lubophelela kwi-ATP-Citrate iLyase, ivimba indlela ye-acetyl-CoA yokuguqula i-fat;
Izifundo zeklinikhi zibonise ukuba kunciphisa i-fat synthesis nge-40% -70% kwiiyure ze-8-12 emva kokutya.

2. Ukukhuthaza ukutshiswa kwaMafutha
Yenza i-AMPK ibonise indlela yokubonisa kwaye ikhawulezise i-acid acid β-oxidation kwi-muscle kunye nesibindi;
Umyinge wepesenti yamafutha omzimba wezifundo wehle nge-2.3% kwilingo leeveki ezili-12.

3. Lawula ukuKhanya
Ukwandisa amanqanaba e-serotonin yengqondo (i-5-HT) kunye nokunciphisa ukutya okunekhalori ephezulu;
Isebenzisana ne-cellulose yesityalo ukwandisa ukuhlutha kwesisu.

●Siyintoni isicelo seI-Hydroxycitric Acid ?
1. Ulawulo lobunzima:
Njengesithako esisisiseko kwi-capsules yokulahlekelwa kwesisindo kunye ne-powder replacement powder, i-dose ephakanyisiweyo yi-500-1000 mg / ngosuku (ithathwe ngamaxesha angama-2-3);
Idityaniswe ne-L-carnitine kunye ne-caffeine, inokuphucula umphumo wokutshisa amanqatha.

2. Isondlo sezemidlalo:
Ukuphucula ukusebenza kokunyamezela kunye nokunciphisa ukukhathala emva kokuzivocavoca, okufanelekileyo kubadlali bezemidlalo kunye nabantu abanomzimba.

3. Impilo yeMetabolic:
Ukuphucula ukuqonda kwe-insulin kwaye uncedise ekulawuleni iswekile yegazi kunye negazi lipids (i-LDL-C iyancipha malunga ne-15%).

4.Ishishini lokuTya:
Njengeasidi yendalo esetyenziswa kwiziselo ezineswekile ephantsi, nayo inomsebenzi wokulawula imetabolism.

● Iingcebiso:
1. Iimpendulo ezingalunganga:
Iidosi eziphezulu zei-hydroxycitric acid(> 3000mg / ngosuku) kunokubangela intloko ebuhlungu, isicaphucaphu, kunye nokuphazamiseka kwesisu;
Ukusetyenziswa kwexesha elide kufuna ukubeka iliso ekusebenzeni kwesibindi (amatyala ambalwa axelwe ngokunyuka kwama-transaminases).

2. IiContraindications:
Abasetyhini abakhulelweyo kunye nabasetyhini abancancisayo (idatha engonelanga yokhuseleko);
Izigulane zesifo seswekile (ukudibanisa neziyobisi ze-hypoglycemic zingabangela i-hypoglycemia);
Abasebenzisi beziyobisi be-Psychotropic (ummiselo we-5-HT unokuchaphazela ukusebenza kweziyobisi).

3. Ukusebenzisana kweziyobisi:
Gwema ukusetyenziswa okudibeneyo kunye ne-antidepressants (ezifana ne-SSRIs) ukukhusela umngcipheko we-5-HT syndrome.
● ENTSHA GREEN Unikezelo lomgangatho ophezuluI-Hydroxycitric AcidUmgubo