I-Baclofen Powder yeNdalo ecocekileyo yoMgangatho weBaclofen Powder

I-Baclofen, eyaziwa ngokuba yi-Becomphin, i-Becomphin, kunye ne-Li Luxing, igama leziyobisi yi-chirosol, i-Liolexin, i-chloraminobutyric acid, iphuma kwi-gamma-aminobutyric acid, ichiza le-spasmolytic, ngenxa yesenzo senkqubo ye-nervous central kunye ne-spinal cord skeletal muscle relaxant, i-sedative. Inokuthintela ukukhutshwa kwe-amino acids enomdla njenge-glutamic acid kunye ne-aspartate ngokuvuselela i-receptor, kwaye ngaloo ndlela inqanda ukuhanjiswa kwe-synaptic enye kunye ne-multi-synaptic reflex kwingqondo kunye nentambo yomgogodla wenkqubo ye-nervous central, ukwenzela ukuba idlale indima ye-spasmotic. Ngokweklinikhi, isetyenziswe njengolungiselelo lobuhlanga kunyango lwe-muscle ye-Chemicalbook spasticity ukususela phakathi kwe-1960s. Uphononongo lwakutsha nje luye lwafumanisa ukuba le mveliso inokunciphisa kakhulu i-reflux ye-gastroesophageal kwaye iphucule iimpawu zayo, ikhulule ngokufanelekileyo iimpawu ze-dystonia ebantwaneni, kwaye iphathe ukungasebenzi kakuhle kokuchama emva kokulimala okuphakathi kwe-spinal refractory. Ukongeza, ukusetyenziswa kweklinikhi yonyango lwenaliti ye-intrathecal kunokuphucula ngakumbi ukusebenza kweklinikhi kunye nokulungelelanisa umthamo weziyobisi nangaliphi na ixesha ukuzinzisa isiphumo sonyango. Kwiminyaka eyi-10 edlulileyo, ukusetyenziswa kweklinikhi ye-baclofen ye-muscle epholileyo yenze inkqubela phambili enkulu, ngakumbi kunyango lokuvuselela i-nerve yokunciphisa ithoni yemisipha kunye nokunciphisa intlungu.