● Ke Eng?Thiamine Hydrochloride ?
Thiamine hydrochloride ke mofuta oa hydrochloride oa vithamine B₁, ka foromo ea lik'hemik'hale C₁₂H₁₇ClN₄OS·HCl, boima ba molek'hule 337.27, le nomoro ea CAS 67-03-8. Ke phofo ea kristale e tšoeu ho isa ho bosehla bo bosoeu bo nang le monko o fokolang oa bran ea raese le tatso e babang. Ho bonolo ho monya mongobo sebakeng se omileng (e ka monya mongobo oa 4% ha e pepesehetse moea). Lintho tsa mantlha tsa 'mele le tsa lik'hemik'hale li kenyelletsa:
Sollubility:E qhibiliha haholo metsing (1g/mL), e qhibiliha hanyane ka har'a ethanol le glycerol, 'me ha e khone ho qhibiliha ka har'a metsoako ea tlhaho e kang ether le benzene.
Botsitso:E tsitsitseng sebakeng se nang le asiti (pH 2-4) mme e khona ho mamella mocheso o phahameng oa 140 ° C; empa e senyeha ka potlako litharollong tse sa nke lehlakore kapa tsa alkaline 'me e sebelisoa habonolo ke mahlaseli a ultraviolet kapa li-redox agents.
Litšobotsi tsa ho lemoha:E sebetsana le ferric cyanide ho hlahisa ntho e putsoa ea fluorescent "thiochrome", e fetohang motheo oa tlhahlobo ea bongata38.
Mokhoa o ka sehloohong oa lefats'e oa ho lokisetsa ke lik'hemik'hale tsa lik'hemik'hale, tse sebelisang acrylonitrile kapa β-ethoxyethyl propionate e le lisebelisoa tse tala 'me li hlahisoa ka condensation, cyclization, replacement le mehato e meng, ka bohloeki bo fetang 99%.
●Melemo ea Ke EfeThiamine Hydrochloride ?
Thiamine hydrochloride e fetoloa sebopeho se sebetsang sa thiamine pyrophosphate (TPP) 'meleng oa motho,' me e bapala mesebetsi e mengata ea 'mele:
1. Moko oa metabolism ea matla:joalo ka coenzyme ea α-ketoacid decarboxylase, e nka karolo ka kotloloho ts'ebetsong ea phetoho ea tsoekere ho ATP. Ha e haella, e lebisa ho bokelleng ha pyruvate, e bakang lactic acidosis le mathata a matla.
2. Tšireletso ea tsamaiso ea methapo:Ho boloka tsamaiso e tloaelehileng ea methapo ea kutlo. Khaello e matla e baka beriberi, e nang le matšoao a tloaelehileng a kenyeletsang peripheral neuritis, muscular atrophy le ho hloleha ha pelo. Ho ea ka histori, e bakile seoa se seholo Asia, se bolaeang batho ba likete tse makholo selemo le selemo.
3. Boleng ba lipatlisiso bo hlahang:
Tšireletso ea myocardial:10μM ea mahloriso e ka hanyetsa tšenyo ea sele ea myocardial e bakoang ke acetaldehyde, ea thibela ts'ebetso ea caspase-3, 'me ea fokotsa sebopeho sa protheine carbonyl.
Anti-neurodegeneration:Litekong tsa liphoofolo, khaello e ka lebisa ho bokelleng ho sa tloaelehang ha protheine ea β-amyloid bokong, e amanang le lefu la Alzheimer's.
Lihlopha tse kotsing e kholo ea khaello li kenyelletsa:tšebeliso ea nako e telele ea raese e hloekisitsoeng e tšoeu le phofo, lino tse tahang (ethanol e thibela ho kenngoa ha thiamine), bakhachane le bakuli ba nang le letšollo le sa foleng.
●Kopo ea Ke EfeThiamine Hydrochloride ?
1. Indasteri ea lijo (kabelo e kholo):
Lintlafatso tsa limatlafatsi:e kenyellelitsoe lihlahisoa tsa lijo-thollo (3-5mg/kg), lijo tsa masea (4-8mg/kg), le lino tsa lebese (1-2mg/kg) ho lefella tahlehelo ea limatlafatsi e bakoang ke ho sebetsa hantle.
Mathata a tekheniki:Hobane ho bonolo ho bola sebakeng sa alkaline, lintho tse tsoang ho thiamine nitrate hangata li sebelisoa e le sebaka sa lijo tse halikiloeng.
2. Lekala la bongaka:
Lisebelisoa tsa kalafo:liente li sebelisoa bakeng sa phekolo ea tšohanyetso ea beriberi (ho hloleha ha methapo ea kutlo / pelo), 'me litokisetso tsa molomo li sebelisoa e le phekolo e thusang bakeng sa neuritis le indigestion.
Phekolo e kopaneng:e kopantsoe le lisebelisoa tsa magnesium ho ntlafatsa katleho ea Wernicke encephalopathy le ho fokotsa sekhahla sa ho ipheta.
3. Temo le biotechnology:
Li-inducers tse hanyetsanang le mafu a lijalo:Kalafo ea mahloriso ea 50mM ea raese, likomkomere, joalo-joalo, e kenya tšebetsong liphatsa tsa lefutso tse amanang le pathogen (liphatsa tsa lefutso tsa PR), le ho matlafatsa ho hanyetsa li-fungus le likokoana-hloko.
Lisebelisoa tsa lijo:Ntlafatsa ts'ebetso ea ts'ebetso ea ts'ebetso ea tsoekere ho liphoofolo tse ruuoang le likhoho, haholo maemong a khatello ea mocheso (keketseho ea tlhoko ea ho tsoa mofufutso).
● NEWGREEN Supply High QualityThiamine HydrochloridePhofo
Nako ea poso: Jun-30-2025
