●Ke Eng?L-Citrulline?
L-Citrulline ke non-proteinogenic α-amino acid, e rehelletsoeng ka bo-rasaense ba ileng ba qala ho e arola ho lero la mahapu (Citrullus lanatus) ka 1930. Lebitso la eona la lik'hemik'hale ke (S) -2-amino-5-ureidopentanoic acid, e nang le mokhoa oa molek'hule oa C₆H₁₃1 N₃₃9 ea CAS ea nomoro ea 5 ea molek'hule ea 5 ₃9 ea boima ba CAS. 372-75-8237. Tlhahiso ea morao-rao ea indasteri e etsahala haholo ka litsela tse peli:
Tlhaho ea tlhaho: e arohaneng le limela tsa cucurbitaceae tse kang lehapu le likomkomere, empa ka katleho e tlaase le litšenyehelo tse phahameng;
Biosynthesis: tlhahiso ea catalytic potolohong ea urea e sebelisang ornithine le carbamoyl phosphate e le substrates, kapa phetoho ea oxidative ea arginine tlas'a ketso ea nitric oxide synthase (NOS).
Lintho tsa 'mele le tsa lik'hemik'haleea L-Citrulline :
Thepa le solubility: phofo e tšoeu ea kristale, tatso e bolila hanyane; qhibilihang ha bonolo ka metsing (solubility 200g/L, 20℃), hoo e batlang e sa qhibilihe ka har'a metsoako ea lintho tse phelang tse kang ethanol le ether;
Lisebelisoa tsa optical: ho potoloha ho itseng + 24.5 ° ~ + 26.8 ° (c = 8, 6N HCl), e leng letšoao la bohlokoa bakeng sa boitsebiso ba 'nete;
Litšitiso tsa botsitso: ho nahanela khanya le mocheso, ntlha ea ho qhibiliha ke 214-222 ℃ (mefuta e fapaneng ea kristale), ho bonolo ho senyeha ka holimo ho 100 ℃; e hloka ho koaloa le ho bolokoa hole le khanya le mocheso o tlase (0-5 ℃);
Litekanyetso tsa ho laola boleng: lihlahisoa tsa lihlahisoa tsa meriana li hloka litšepe tse boima ≤10ppm, metsi a mangata ≤0.30%, le masala a ho chesa ≤0.10% (AJI92 e tloaelehileng).
●Ke Eng SeoMelemoEaL-Citrulline ?
Boleng ba mantlha ba L-citrulline bo matleng a eona a ho fetolela arginine le ho lokolla nitric oxide (NO), ka hona e kenya tšebetsong litlamorao tse ngata tsa 'mele:
Tšireletso ea pelo
Fokotsa khatello ea methapo le ho ntlafatsa phallo ea mali ka NO-mediated vascular smooth muscle relaxation;
Phuputso e entsoeng ke Univesithi ea Texas A & M United States e tiisitse hore mochine oa eona oa vasodilatory effect o tšoana le "Viagra ea tlhaho", ka tekanyo ea ntlafatso ea 40% bakeng sa ho se sebetse ha erectile mme ha ho na litla-morao tsa lithethefatsi.
Metabolism le taolo ea 'mele oa ho itšireletsa mafung
Ho potlakisa potoloho ea urea ea sebete, ho potlakisa metabolism ea ammonia, le ho fokotsa khatello ea ammonia maling;
Eketsa ts'ebetso ea macrophage le ho ntlafatsa bokhoni ba antiviral (joalo ka sekhahla sa tumello ea kokoana-hloko ea ntaramane e eketsehile ka 35%).
Ts'ebetso ea methapo le makoloi
Tšela mokoallo oa mali-bokong ho eketsa maemo a NO bokong le ho ntlafatsa bokhoni ba ho fumana lintlha tsa mohopolo;
Neutralize mefuta ea oksijene e sebetsang (ROS) e hlahisoang ke boikoetliso le ho eketsa nako ea mamello ea mesifa ka 22%.
●Ke Eng SeoKopoOf L-Citrulline?
1. Indasteri ea Bophelo bo Botle:
Lihlahisoa tsa phepo ea lipapali: li kopantsoe le li-amino acid tsa branched-chain, khatello ea mali ea ketone ka mor'a ho ikoetlisa e bolokiloe ka holimo ho 4mM, 'me nako ea ho hlaphoheloa ha mesifa e khutsufatsoa ke 30% (kabelo ea maraka ea lefats'e ka 2024 ke 45%);
Ho ntlafatsa ts'ebetso ea thobalano: citrulline e ka khothaletsa vasodilation le ho ntlafatsa ho se sebetse ha erectile
2. Indasteri ea Lijo:
Tlhokomelo ea tlhaho: thibela ho ata ha likokoana-hloko lihlahisoa tsa nama ea metsing, 'me palo eohle ea kolone ea salmon e nang le sehatsetsing e fokotsehile ka 90%;
Li-additives tse sebetsang: "L-Citrulline + γ-aminobutyric acid" yogurt e sebetsang, e laola ka mokhoa o lumellanang khatello ea methapo le matšoenyeho.
3. Biomedicine:
Kalafo ea lefu la Alzheimer: kenya tšebetsong tsela ea cAMP/PI3K-Akt, e ntlafatse polelo ea neurotrophic factor (BDNF) e tsoang bokong, le ho ntlafatsa bokhoni ba ho ithuta le ho hopola litoeba tsa mohlala ka 40%;
Sistimi ea phepelo ea liphatsa tsa lefutso: joalo ka pDNA nanocarrier, ts'ebetso ea phetisetso e phahame ka makhetlo a 100 ho feta ea liposomes, mme e tla kena tekong ea bongaka ea Phase I bakeng sa kalafo ea tumor ea boko ka 2025.
4. Cosmetic Innovation
E kopantsoe le li-polysaccharide moisturizers, katleho ea ho phekola letlalo le omeletseng e feta 80%;
E thibela phetiso ea matšoao a methapo ho pruritic dermatitis le ho lokisa tšebetso ea mokoallo oa stratum corneum.
●Newgreen Supply High QualityL-CitrullinePhofo
Nako ea poso: Jul-16-2025
