●Ke eng Caffeic Acid?
Caffeic acid, lebitso la lik'hemik'hale 3,4-dihydroxycinnamic acid (molek'hule formula C₉H₈O₄, CAS No. 331-39-5), ke motsoako oa tlhaho oa phenolic acid o fumanoang haholo limela. Ke kristale e mosehla ka ponahalo, e qhibiliha hanyenyane metsing a batang, e qhibiliha habonolo metsing a chesang, ethanol le ethyl acetate, e nang le ntlha e qhibilihisang ea 194-213 ℃ (mekhoa e fapaneng e fapana), e khubelu ea lamunu ka tharollo ea alkaline, le botala bo lefifi bo kopane le ferric chloride.
Mehloli ea bohlokoa ea tlhahiso e kenyelletsa:
●Limela tsa meriana:Asteraceae Solidago, sinamone, dandelion (e nang le caffeic acid ≥ 0.02%), Ranunculaceae Cimicifuga rhizome;
●Mehloli ea litholoana le meroho:lemon peel, blueberry, apole, broccoli le meroho ea cruciferous;
●Lisebelisoa tsa seno:linaoa tsa kofi (ka mofuta oa chlorogenic acid esters), veine (e kopantsoeng le tartaric acid).
Theknoloji ea sejoale-joale e sebelisa thekenoloji ea supercritical CO₂ kapa theknoloji ea bio-enzymatic hydrolysis ho hloekisa acid ea caffeic ho tsoa lihlahisoa tse tala tsa semela, ka bohloeki bo fetang 98%, e kopanang le litekanyetso tsa sehlopha sa meriana le litlolo.
● Melemo ea Caffeic Acid?
Caffeic acid e bonts'a mesebetsi e mengata ea tlhaho ka lebaka la sebopeho sa eona sa o-diphenolic hydroxyl:
1. Antioxidant le Anti-Inflammatory:
E na le matla a matla ka ho fetisisa a mahala a scavenging har'a hydrogenated cinnamic acid, 'me katleho ea eona ke makhetlo a 4 a vithamine E. E thibela liphetoho tsa ketane ea lipid peroxidation ka ho etsa libopeho tsa quinone;
E thibela leukotriene synthesis (e laola ho itšireletsa mafung le ho ruruha), e fokotsa tšenyo ea DNA ea letlalo e bakoang ke UV, 'me e fokotsa erythema index ka 50%.
2. Tšireletso ea Metabolic le Pelo:
Asiti ea caffeineE thibela oxidation ea low-density lipoprotein (LDL) mme e fokotsa sebopeho sa letlapa la atherosclerotic;
Litekong tsa litoeba tse nang le mafura a mangata, ho bokella mafura a visceral ho fokotsehile ka 30% le sebete sa triglycerides se fokotsehile ka 40%.
3. Neuroprotection le Anti-Tumor:
Pontšo ea insulin ea hippocampal e ntlafalitsoeng, ts'ebetso e ntlafalitsoeng ea memori mefuteng ea lefu la Alzheimer's, le ho fokotsa protheine ea β-amyloid;
E thibela ho ata ha lisele tsa mofetše oa fibrosarcoma mme e thibela kholo ea hlahala ka ho fokotsa DNA methylation.
4. Hemostasis le Keketso ea Leukocyte:
E fokotsa li-microvessels mme e ntlafatsa ts'ebetso ea lintlha tsa coagulation. E sebelisoa ka bongaka bakeng sa ho buoa hemostasis le leukopenia ka mor'a chemotherapy, ka sekhahla se sebetsang sa ho feta 85%.
● Likopo Tsa Caffeic Acid ?
Tšebeliso ea asiti ea caffeic e akaretsa likarolo tse ngata:
1. Meriana:matlapa a caffeic acid (hemostasis, keketseho ea lisele tse tšoeu tsa mali), lithethefatsi tse lebisitsoeng ho anti-tumor (teko ea kliniki ea succinic acid phase II)
2. Litlolo:setlolo se sireletsang letsatsi (synergistic zinc oxide ho eketsa boleng ba SPF), motsoako o mosoeu (thibela tyrosinase, sekhahla sa inhibition sa melanin 80%).
3. Indasteri ea Lijo:li-preservatives tsa tlhaho (ho lieha ho hlahisa lipids ea tlhapi), lino tse sebetsang (anti-oxidation le anti-inflammatory), tšebeliso ea synergistic ea ascorbic acid.
4. Temo le Tšireletso ea Tikoloho:likokoana-hloko tsa tikoloho (thibela k'hothone bollworm protease), phetoho ea boea (thepa ea antioxidant e eketsehile ka 75%).
●Melao ea Tšebeliso le TšireletsehoEaCaffeic Acid
Tekanyo ea meriana:Matlapa a Caffeic acid: 0.1-0.3g hanngoe, makhetlo a 3 ka letsatsi, matsatsi a 14 e le mokhoa oa phekolo, palo ea liplatelete e hloka ho hlahlojoa (e fokotsoe ha> 100 × 10⁹/L, e hloka ho buisana le ngaka pele e sebelisoa);
Contraindications:Contraindicated bakeng sa bakhachane le bakuli ba hypercoagulable boemo; e sebelisoang ka hloko ho bakuli ba nang le ho se sebetse ha sebete le liso tsa ka mpeng.
Li-cosmetic additives:0.5% -2% e kenyellelitsoe lihlahisoa tse soeufatsang, tse qhibilihisitsoeng pele ka har'a ethanol ebe li kenngoa ka har'a matrix a metsi ho qoba ho kopana.
Litlhoko tsa polokelo:E tiisitsoe sebakeng se lefifi, sehatsetsing ho 2-8 ℃, se sebetsang lilemo tse 2 (litokisetso tsa metsi li hloka ho sireletsoa ho oxidation le ho senyeha)
●NEWGREEN PhepeloCaffeic AcidPhofo
Nako ea poso: Jul-23-2025
