●Berberine ke Eng?
Berberine ke alkaloid ea tlhaho e ntšitsoeng metsong, kutung le makhapetla a limela tse fapaneng, joalo ka Coptis chinensis, Phellodendron amurense le Berberis vulgaris. Ke motsoako o ka sehloohong o sebetsang oa Coptis chinensis bakeng sa phello ea antibacterial.
Berberine ke kristale e mosehla e bōpehileng joaloka nale e nang le tatso e babang. Sejo se ka sehloohong se babang ho Coptis chinensis ke berberine hydrochloride. Ena ke alkaloid ea isoquinoline e ajoang litlama tse fapaneng tsa tlhaho. E fumaneha ho Coptis chinensis ka sebopeho sa hydrochloride (berberine hydrochloride). Liphuputso li fumane hore motsoako ona o ka sebelisoa ho phekola lihlahala, lefu la sebete, mafu a pelo, khatello ea mali, ho ruruha, tšoaetso ea baktheria le kokoana-hloko, letšollo, lefu la Alzheimer le ramatiki.
● Melemo ea Berberine ke Efe ea Bophelo bo Botle?
1.Antioxidant
Tlas'a maemo a tloaelehileng, 'mele oa motho o boloka ho leka-lekana pakeng tsa li-antioxidants le li-prooxidants. Khatello ea oxidative ke ts'ebetso e kotsi eo e ka bang mokena-lipakeng oa bohlokoa oa tšenyo ea sebopeho sa lisele, ka hona e baka maemo a fapaneng a mafu a kang lefu la pelo, mofets'e, mafu a methapo le lefu la tsoekere. Tlhahiso e feteletseng ea mefuta ea oksijene e sebetsang (ROS), hangata ka ho hlohlelletsa ho feteletseng ha NADPH ka li-cytokine kapa ka ketane ea lipalangoang tsa elektronike ea mitochondrial le xanthine oxidase, e ka lebisa khatellong ea oxidative. Liteko li bontšitse hore berberine metabolites le berberine li bonts'a ts'ebetso e ntle haholo -OH ea ho senya, e batlang e lekana le matla a antioxidant vithamine C. Tsamaiso ea berberine ho likhoto tsa lefu la tsoekere e ka shebella ho eketseha ha mosebetsi oa SOD (superoxide dismutase) le ho fokotseha ha MDA (letšoao la maemo a lipid peroxidation). Liphetho tse ling li bonts'a hore ts'ebetso ea ho hloekisoa ha berberine e amana haufi-ufi le ts'ebetso ea eona ea ferrous ion chelating, 'me sehlopha sa C-9 hydroxyl sa berberine ke karolo ea bohlokoa.
2. Anti-tumor
Ho bile le litlaleho tse ngata mabapi le phello e khahlanong le mofetše oaberberine. Liphuputso tse fapa-fapaneng lilemong tsa morao tjena li bontšitse hore berberine ke ea bohlokoa haholo kalafong ea adjuvant ea mafu a tebileng a mofets'e joalo ka mofets'e oa mahe a bomme, mofets'e oa endometrial, mofets'e oa popelo, mofets'e, mofets'e oa matšoafo, mofets'e oa colorectal, mofets'e oa liphio, mofets'e oa senya le mofets'e oa senya. Berberine e ka thibela ho ata ha lisele tsa hlahala ka ho sebelisana le lipheo le mekhoa e fapaneng. E ka fetola polelo ea li-oncogenes le liphatsa tsa lefutso tse amanang le kankere ho finyella morero oa ho laola mosebetsi oa li-enzyme tse amanang le tsona ho thibela ho ata.
3.Ho Fokotsa Lipids tsa Mali Le ho Sireletsa Sisteme ea pelo
Berberine e bapala karolo ea bohlokoa kalafong ea mafu a pelo le methapo mme e na le lits'ebetso tse fapaneng. Berberine e finyella sepheo sa anti-arrhythmia ka ho fokotsa liketsahalo tsa ho otla pele ho nako ea ventricular le ho thibela ho etsahala ha ventricular tachycardia. Taba ea bobeli, dyslipidemia ke kotsi e kholo ea lefu la pelo, e khetholloang ke maemo a phahameng a k'holeseterole eohle, triglycerides, le low-density lipoprotein cholesterol (LDL), le maemo a fokotsehileng a high-density lipoprotein (HDL), le berberine e ka boloka botsitso ba matšoao ana ka matla. Hyperlipidemia ea nako e telele ke sesosa sa bohlokoa sa ho theha letlapa la atherosclerotic. Ho tlalehoa hore berberine e ama li-receptor tsa LDL ho li-hepatocyte ho fokotsa maemo a k'holeseterole ea serum ea batho ho hepatocyte. Eseng hoo feela,berberinee na le phello e ntle ea inotropic mme e sebelisitsoe ho phekola ho hloleha ha pelo ea congestive.
4.E theola Tsoekere ea Mali 'me e Laola Endocrine
Diabetes mellitus (DM) ke lefu la metabolism le khetholloang ke maemo a phahameng a tsoekere maling (hyperglycemia) a bakoang ke ho sitoa ha lisele tsa pancreatic B ho hlahisa insulin e lekaneng, kapa ho lahleheloa ke karabelo e sebetsang ea lithane tsa insulin. Phello ea hypoglycemic ea berberine e fumanoe ka phoso lilemong tsa bo-1980 kalafong ea bakuli ba nang le lefu la tsoekere ba nang le letšollo.
Liphuputso tse ngata li bontšitse seoberberinee theola tsoekere maling ka mekhoa e latelang:
● E thibela oxidation ea tsoekere ea mitochondrial le ho susumetsa glycolysis, ka mor'a moo e eketsa metabolism ea tsoekere;
● E fokotsa maemo a ATP ka ho thibela mosebetsi oa mitochondrial sebeteng;
● E thibela ts'ebetso ea DPP 4 (serine protease e fumanehang hohle), kahoo e qhekella li-peptide tse itseng tse sebetsang ho eketsa maemo a insulin ka pel'a hyperglycemia.
● Berberine e na le phello e molemo ho ntlafatseng ho hanyetsa insulin le ho sebelisoa ha tsoekere ka har'a lisele ka ho fokotsa lipids (haholo-holo triglycerides) le boemo ba plasma ea mafura a mahala.
Kakaretso
Matsatsing ana,berberinee ka etsoa ka maiketsetso le ho fetoloa ka mekhoa ea boenjiniere ba kristale. E na le theko e tlase le theknoloji e tsoetseng pele. Ka nts'etsopele ea lipatlisiso tsa bongaka le ho teba ha lipatlisiso tsa lik'hemik'hale, berberine e tla bontša liphello tse ngata tsa meriana. Ka lehlakoreng le leng, berberine ha e fumane feela liphello tse tsotehang lipatlisisong tsa setso tsa meriana ea likokoana-hloko, likokoana-hloko, li-anti-inflammatory, anti-tumor, anti-diabetic, le phekolo ea mafu a pelo le a cerebrovascular, empa hape le moralo oa eona oa boenjiniere ba kristale le tlhahlobo ea morphological e fumane tlhokomelo e kholo. Ka lebaka la ts'ebetso ea eona ea bohlokoa le chefo e tlase le litlamorao, e na le monyetla o moholo ts'ebelisong ea bongaka 'me e na le menyetla e mengata. Ka nts'etsopele ea biology ea lisele, mokhoa oa pharmacological oa berberine o tla hlakisoa ho tloha boemong ba lisele tsa cellular esita le maemo a limolek'hule le sepheo, ho fana ka motheo oa khopolo-taba bakeng sa ts'ebeliso ea eona ea bongaka.
● NEWGREEN SupplyBerberine/Liposomal Berberine Powder/Capsules/Tablets
Nako ea poso: Oct-28-2024
