●Ke eng Andrographis Paniculata Extract?
Andrographis paniculata, e tsejoang hape e le "thabo ea nako e le 'ngoe" le "joang bo babang", ke semela sa selemo le selemo sa herbaceous sa lelapa la Acanthaceae. E hlaha Asia Boroa joalo ka India le Sri Lanka, 'me hona joale e ajoa haholo libakeng tse mongobo le tse chesang joalo ka Guangdong le Fujian naheng ea China. Semela sohle se latsoa ho baba haholo, ka kutu e sekoere, makhasi a fapaneng, le nako ea lipalesa ea Phato-Lwetse. Meriana ea setso ea Sechaena e sebelisa liphello tsa eona tsa ho tlosa mocheso le ho tlosa chefo, ho pholisa mali le ho fokotsa ho ruruha ho phekola sefuba, feberu, letšollo, liso le ho longoa ke noha. Indasteri ea sejoale-joale e ntša metsoako e sebetsang ho tloha ho lithupa le makhasi ka ho ntšoa ha CO₂ ea supercritical le bio-enzymatic hydrolysis technology ho etsa phofo e tloaelehileng e nang le andrographolide content ea 8% -98%, e khothalletsang ntlafatso ea eona ho tloha meriana ea setso ea litlama ho ea ho lisebelisoa tse tala tsa machaba.
Lisebelisoa tsa mantlha tse sebetsang tsaAndrographis Paniculata Extractske diterpenoid lactone metsoako, e ikarabellang bakeng sa 2% -5%24, haholo-holo ho kenyelletsa:
- Andrographolide:formula ea molek'hule C₂₀H₃₀O₅, e etsang 30% -50%, ke ntho e ka sehloohong e sebetsang bakeng sa antibacterial le anti-inflammatory.
- Dehydroandrographolide:formula ea molek'hule C₂₀H₂₈O₄, ntlha ea ho qhibiliha 204 ℃, e nang le ts'ebetso ea bohlokoa e khahlanong le hlahala.
- 14-Deoxyandrographolide:formula ea molek'hule C₂₀H₃₀O₄, e nang le katleho e ikhethang khahlanong le leptospirosis.
- Neoandrographolide:formula ea molek'hule C₂₆H₄₀O₈, ho qhibiliha ha metsi hantle, ho loketse litokisetso tsa molomo.
Ntle le moo, li-flavonoids, li-phenolic acid le likarolo tsa oli tse feto-fetohang li ntlafatsa ts'ebetso ea antioxidant le immunomodulatory.
●Melemo ea Ke Efe Andrographis Paniculata Extract?
1. Immunomodulation le Anti-Tshwaetso
Antibacterial and antiviral: Andrographolide e na le sekhahla sa ho thibela ho feta 90% ho Staphylococcus aureus le Shigella dysenteriae, 'me katleho ea eona ea bongaka ea ho phekola bacillary dysentery e bapisoa le chloramphenicol. Mokelikeli oa eona oa metsi o ka fokotsa sekhahla sa feberu ka 30% mme oa khutsufatsa nako ea sefuba ka 50%.
Immunoenhancement: Ka ho kenya tšebetsong macrophages le T lymphocyte, e ka eketsa boemo ba CD4⁺ lymphocyte ho bakuli ba HIV (data ea kliniki: 405→ 501/mm³, p=0.002).
2. Thibelo ea Anti-Tumor le Angiogenesis
Ka ho toba khahlanong le hlahala: Dehydroandrographolide e ka thibela ho hōla ha lihlahala tse fetisitsoeng tsa W256 le ho thibela ho ata ha lisele tsa kankere ka mokhoa o itšetlehileng ka tekanyo.
Anti-angiogenesis: Andrographolide e thibela tumor angiogenesis ka ho theola polelo ea VEGFR2 le ho thibela tsela ea pontšo ea ERK/p38, ka IC₅₀ ea 100-200μM.
3. Metabolism le Tšireletso ea 'mele
Tšireletso ea sebete le ho fokotsa lipid: Andrographolide e boloka maemo a glutathione mme e fokotsa malondialdehyde (MDA) ka mohlala oa kotsi ea sebete ea carbon tetrachloride ka 40%, e molemo ho feta silymarin.
Tšireletso ea pelo: E laola tekano ea nitric oxide/endothelin, e liehisa lefu la atherosclerosis, le ho fokotsa maemo a mali a meutlanyana ea liteko.
4. Anti-Inflammatory Le Antioxidant
Motsoako oa metsi oa kutu o na le matla a matla ka ho fetisisa a ho senya li-radicals tsa mahala (IC₅₀=4.42μg/mL), e sebetsang ka makhetlo a 4 ho feta li-antioxidants tsa maiketsetso 'me e loketse mafu a sa foleng a ho ruruha.
●Ke Likopo life tsaAndrographis Paniculata Extract ?
1. Meriana le Phekolo ea Meriana
Lithethefatsi tse thibelang tšoaetso: li sebelisetsoa letšollo la baktheria, ente ea pneumonia le litokisetso tsa molomo bakeng sa pharyngitis, ka tekanyo ea phekolo ea meriana e fetang 85%.
Lithethefatsi tse lebisitsoeng ho anti-tumor: Derivative ea Andrographolide "Andrographine" e kene litekong tsa bongaka tsa Phase II bakeng sa leukemia le lihlahala tse tiileng.
Taolo ea mafu a sa foleng: kalafo e thusang ea lefu la tsoekere la retinopathy (0.5-2mg/kg/letsatsi) le ramatiki ea ramatiki (1-3mg/kg/letsatsi).
2. Ho Hlōla Liphoofolo Le Ho Hōlisa Ka Botala
Mefuta e meng ea lithibela-mafu: Metsoako ea Compound Andrographis paniculata feed e fokotsa sekhahla sa letšollo la likolobe le ho eketsa sekhahla sa ho phela ha likhoho tsa nama; ho eketsa 4% e nkiloeng ho fepa ea carp, tekanyo ea boima ba 'mele e fihla ho 155.1%,' me tekanyo ea phepelo ea phepelo e ntlafalitsoe ho 1.11.
Thibelo le taolo ya malwetse: Ente ya Andrographis paniculata e alafa nyumonia ya dikolobe le enteritis, ka sekhahla sa pheko sa 90% le sekhahla sa batho ba shoang sa 10%.
3. Lijo tsa Bophelo bo Botle le Lik'hemik'hale Tsa Letsatsi le Letsatsi
Lijo tse sebetsang: Andrographis paniculatantshali-capsules (200mg ka letsatsi) li qalisoa limmarakeng tsa Europe le Amerika bakeng sa taolo ea 'mele ea ho itšireletsa mafung le ho thibela serame.
Lihlahisoa tsa tlhokomelo ea letlalo: Eketsa linthong tse thibelang ho ruruha le litlolo tse sireletsang letlalo letsatsing ho imolla tšenyo ea UV le bofubelu ba letlalo le bonolo.
4. Liphello Tse Hlaha
Lithethefatsi tse khahlanong le angiogenic: Nts'etsopele ea litokisetso tse lebisitsoeng bakeng sa lihlahala le lefu la tsoekere retinopathy e fetohile tataiso ea bohlokoa ea baeloji ea maiketsetso.
Tlhokomelo ea bophelo bo botle ba liphoofolo tse ruuoang lapeng: Li-anti-inflammatory le immunomodulatory supplements bakeng sa lintja le likatse li hlahisoa 'marakeng oa Amerika Leboea, ka sekhahla sa kholo sa selemo sa 35%.
●NEWGREEN PhepeloAndrographis Paniculata ExtractPhofo
Nako ea poso: Jul-18-2025
