●Waa maxay Zinc Pyrithion?
Zinc pyrithione (ZPT) waa kakan zinc organic ah oo leh qaacido kelli ah C₁₀H₈N₂O₂S₂Zn (miisaanka kelli 317.7). Magaceedu wuxuu ka yimid maaddooyinka xididka dabiiciga ah ee warshadda Annonaceae Polyalthia nemoralis, laakiin warshadaha casriga ahi waxay qaateen isku-dhafka kiimikada si ay u soo saaraan. Sannadkii 2024-kii, hannaanka patent-ka ee Shiinaha ayaa jabiyay dhuunta nadiifka ah, iyo crotonic acid-ka wasakhaysan waxaa lagu xakameeyay wax ka hooseeya 16ppm iyada oo loo marayo kristalization darajada methanol-acetone, nadiifinta darajada dawooyinka ayaa la kordhiyay ilaa 99.5%.
Astaamaha jireed iyo kiimikaad:
Muuqaalka iyo milanka: caddaan ilaa wax yar oo budada crystalline jaalaha ah, ku dhawaad aan la milmi karin biyaha (<0.1g / 100mL), wax yar oo ku milma ethanol, milanka polyetylen glycol waxay gaari kartaa 2000mg / kg;
Cilladaha xasilloonida: xasaasi u ah iftiinka iyo oksidayaasha, si fudud u hoos u dhigay iftiinka ultraviolet, baakad bunni ah ayaa loo baahan yahay; Fashil la'aanta pH <4.5 ama> 9.5, pH ugu fiican waa 4.5-9.5;
Burburka kulaylka barta muhiimka ah: deggan 120 saacadood at 100 ℃, laakiin si degdeg ah u qudhuntay ka sarreeya 240 ℃;
Isqabqabsi la'aanta: waxay ku soo da'da cationic surfactants, chelates iyo midabyo leh ion bir/naxaas ah (xitaa 1ppm waxay keeni kartaa in alaabtu isu rogaan huruud).
●Maxay YihiinFaa'iidooyinkaee Zinc Pyrithion ?
ZPT waxay ku guulaysataa jeermis-samaynta ballaaran (oo wax ku ool u ah 32 nooc oo noolaha) iyada oo loo marayo hannaan is-weydaarsiga ion gaar ah, gaar ahaan Malassezia, dembiilaha qanjirrada, oo leh MIC sida hooseeya 8ppm:
1. Ion Burburinta Si tartiib ah
Deegaanka acidic ah, H⁺ waxaa la geliyaa bakteeriyada iyo K⁺ waa la soo saaraa, iyo deegaanka alkaline, Na⁺ / Mg²⁺ waa la bedelay, taas oo burburisa nidaamka gaadiidka nafaqada microbial;
2. Xubinta Unugyada oo Burburay
Gelida bilayer phospholipid, kordhinta qulqulka xuubka oo keenaysa daadinta walxaha unugyada;
3. Xakamaynta Dhaqdhaqaaqa Enzyme
Joojinta silsiladda gaadiidka elektaroonigga ah iyo joojinta enzymes muhiimka ah ee dheef-shiid kiimikaadka tamarta (sida ATP synthase).
Xaqiijinta bukaan-socodka: Kadib markaad isticmaasho shaambo ka kooban 1.5%zIncpyrithion4 toddobaad, cambarka ayaa hoos u dhacay 90%, iyo heerka soo noqnoqda ee dermatitis seborrheic waa la dhimay 60%.
●Maxay YihiinCodsigaOf Zinc Pyrithion?
1. Goobta Kiimikada Maalinlaha ah:
Waxaa loo isticmaali karaa 70% shaambo ka-hortagga-xanuunka, iyadoo lagu daro 0.3%-2%;
Qaar ka mid ah alaabooyinka la isku qurxiyo ayaa laga yaabaa inay xaddidaan isticmaalka zinc pyrithion waxayna u baahan yihiin in lagu calaamadiyo "luug ka dib isticmaalka". Waxaad isticmaali kartaa alaabta kale ee piroctone ethanolamine (OCT).
2. Ka-hortagga Daxalka Warshadaha:
Kacaan-ka-hortagga wasakhda: lagu daray koofiyad oxide si loo joojiyo ku-xidhnaanta barnacle oo loo yareeyo isticmaalka shidaalka 12%;
3. Beeraha iyo Agabka:
Ilaalinta abuur: 0.5% wakiilka dahaarka ayaa ka hortagaya caariyaysi wuxuuna kordhiyaa heerka biqilka 18%;
Fiber-bakteeriyada: Dharka polyester-ka ee la tallaalay ayaa leh heerka bakteeriyada bakteeriyada> 99%.
4. Kordhinta Caafimaadka:
Tijaabada saddexda sababood ee diidmada ah (ma jiro kansar/teratogenicity/mutagenicity), oo loo isticmaalo dahaadhka finanka iyo dahaarka bakteeriyada ee qalabka caafimaadka.
●Talooyin:
Inkasta oo sunta afka ee ba'anof zinc pyrithionwuu hooseeyaa (LD₅₀>1000mg/kg ee jiirarka), digniinaha caafimaad sannadihii u dambeeyay:
Sumowga maqaarka: xidhiidhka muddada-dheer wuxuu keenaa dermatitis xasaasiyadeed, iyo taabashada daboolka indhaha waxay keeni kartaa conjunctivitis;
Caqabado buuxda:
→ Maqaarka jaban (permeability wuxuu kordhiyaa 3 jeer, taasoo keentay soo-gaadhis habaysan);
→ Haweenka uurka leh iyo carruurta (xogta dhexgalka dhiigga iyo maskaxda oo maqan);
Isdhexgalka daroogada: Iska ilaali isticmaalka isku dhafan ee EDTA (cheating zinc ions waxay yareysaa waxtarka daroogada).
●Agab Cusub oo Tayo Sare lehZinc PyrithionBudada
Waqtiga boostada: Jul-09-2025
