● ChiiThiamine Hydrochloride ?
Thiamine hydrochloride ndiyo hydrochloride fomu yevhitamini B₁, ine kemikari formula C₁₂H₁₇ClN₄OS·HCl, molecular weight 337.27, uye CAS nhamba 67-03-8. Ihwo hupfu huchena kusvika kuyero-chena hwekristaro husina kusimba hwemupunga hwebran uye kuravira kunovava. Zviri nyore kutora unyoro munzvimbo yakaoma (inogona kutora 4% mwando kana yaiswa mumhepo). Iyo yakakosha yemuviri uye makemikari zvimiro zvinosanganisira:
Solubility:Yakanyanya kunyungudika mumvura (1g/mL), inonyungudika zvishoma muethanol neglycerol, uye isinganyunguriki muzvinonyungudutsa zveorganic zvakaita seether nebenzene.
Kugadzikana:Yakagadzikana munzvimbo ine acidic (pH 2-4) uye inogona kumira kutonhora kwakanyanya kwe140 ° C; asi inoparara nokukurumidza mukusarerekera kana alkaline mhinduro uye inogadziriswa nyore nyore ne ultraviolet rays kana redox agents.
Maitiro ekuonekwa:Inopindirana neferric cyanide kugadzira chinhu cheblue fluorescent "thiochrome", inova hwaro hwekuongororwa kwehuwandu38.
Nzira yekugadzirira yepasi rose ndeyemakemikari synthesis, inoshandisa acrylonitrile kana β-ethoxyethyl propionate sezvigadzirwa uye inogadzirwa kuburikidza nekugadzirisa, cyclization, kutsiva uye mamwe matanho, nekuchena kunopfuura 99%.
●Ndezvipi ZvakanakiraThiamine Hydrochloride ?
Thiamine hydrochloride inoshandurwa kuita fomu inoshanda ye thiamine pyrophosphate (TPP) mumuviri wemunhu, uye inotamba akawanda mabasa emuviri:
1. Simba metabolism musimboti:se coenzyme ye α-ketoacid decarboxylase, inopindira zvakananga mukugadzirisa kweglucose kuATP. Kana ikashaikwa, inotungamira mukuunganidzwa kwepyruvate, zvichikonzera lactic acidosis uye dambudziko resimba.
2. Nervous system kudzivirira:Kuchengeta zvakajairika conduction ye nerve impulses. Kushaikwa kwakanyanya kunokonzera beriberi, ine zviratidzo zvinowanzoitika zvinosanganisira peripheral neuritis, muscular atrophy, uye kutadza kwemoyo. Kubva kare, zvakakonzera denda guru muAsia, richiuraya mazana ezviuru zvevanhu gore negore.
3. Ukoshi hwekutsvaga huri kubuda:
Kudzivirirwa kwemyocardial:10μM kusungwa kunogona kupikisa acetaldehyde-induced myocardial cell kukuvara, inhibit caspase-3 activation, uye kuderedza mapuroteni carbonyl kugadzirwa.
Anti-neurodegeneration:Mukuedza kwemhuka, kushomeka kunogona kukonzera kuunganidzwa kusingaite kwe β-amyloid protein muuropi, iyo ine hukama nechirwere cheAlzheimer's.
Mapoka ane njodzi huru yekushomeka anosanganisira:kushandiswa kwenguva refu kwemupunga chena uye hupfu, zvidhakwa (ethanol inhibits thiamine absorption), vakadzi vane pamuviri, uye varwere vane chirwere chisingaperi.
●Chii chinonzi Application OfThiamine Hydrochloride ?
1. Indasitiri yezvekudya (mugove mukuru):
Nutrient enhancers:yakawedzerwa kune zvigadzirwa zvezviyo (3-5mg / kg), zvokudya zvevacheche (4-8mg / kg), uye zvinwiwa zvemukaka (1-2mg / kg) kugadzirisa kurasikirwa kwezvokudya zvinokonzerwa nekugadzirisa zvakanaka.
Zvinetso zvehunyanzvi:Nekuti zviri nyore kuora munzvimbo ine alkaline, zvinobva kune zvakaita sethiamine nitrate zvinowanzoshandiswa sechinotsiva muzvikafu zvakabikwa.
2. Nzvimbo yezvokurapa:
Therapeutic applications:majekiseni anoshandiswa pakurapa kwekukurumidzira kweberiberi (neurological / heart failure), uye kugadzirira nemuromo kunoshandiswa semishonga yekubatsira yeuritis uye indigestion.
Combination therapy:yakasanganiswa ne magnesium agents kuvandudza kushanda kweWernicke encephalopathy uye kuderedza chiyero chekudzoka.
3. Zvekurima uye biotechnology:
Zvirwere zvinodzivirira zvirwere:50mM yekusimbisa kurapwa kwemupunga, magaka, nezvimwewo, inomutsa majini ane hukama nehutachiona (PR majini), uye inowedzera kuramba fungi nemavhairasi.
Feed additives:Kuvandudza kushanda kweshuga metabolism muzvipfuyo nehuku, kunyanya munzvimbo dzekupisa kusagadzikana (kuwedzera kudiwa kwekubuda dikita).
● NEWGREEN Supply High QualityThiamine HydrochlorideUpfu
Nguva yekutumira: Jun-30-2025
