• ChiiBifidobacteria Longum ?
Bifidobacterium longum yagara yakabata chinzvimbo chepakati mukuongorora kwevanhu hukama pakati pehutachiona uye hutano. Senhengo yakanyanya kuwanda uye inoshandiswa zvakanyanya yeBifidobacterium genus, saizi yayo yemusika wepasi rose inofungidzirwa kudarika US $ 4.8 bhiriyoni muna 2025, iine musanganiswa wepagore kukura kwe11.3%. Ongororo yemuna 2025 yakaburitswa muNature Microbiology yakasimbisa kuti Bifidobacterium longum inogona kudzora mafambiro ekufunganya kuburikidza neiyo gut-brain axis, zvichiratidza kuti uyu "mudumbu" ari kugadziridza indasitiri yehutano mune imwe danho.
Bifidobacterium longum: Gram-positive, non-spore-forming, uye yakasimba anaerobic, inokura zvakanaka pa36-38°C uye inoshivirira pH ye5.5-7.5. Yayo inoshanda sero density muMRS tsika yepakati inogona kusvika 10 ^ 10 CFU/mL.
Kugadzirira kwemaindasitiri: Uchishandisa tekinoroji yemicroencapsulation, chiyero chekurarama kwesero chinowedzerwa kusvika 92%.
• Ndezvipi ZvakanakiraBifidobacteria Longum?
Zvichienderana nezvidzidzo zvepasirese zvinopfuura zviuru zvitatu, Bifidobacterium longum inoratidza mhedzisiro yebhayoloji yakawanda:
1. Gut Health Management
Microbiome Modulation: Inodzvinyirira hutachiona nekuvhara antimicrobial peptides (yakadai sebifidocin), ichiwedzera kuwanda kweintestinal bifidobacteria ne3-5 nguva.
Mucosal Repair: Inosimudzira occludin protein kutaura, inoderedza intestinal permeability (FITC-dextran permeability yakaderera ne41%), uye inoderedza leaky gut syndrome.
2. Mutengo weImune Regulation
Cytokine Balance:Bifidobacterium longuminokurudzira IL-10 secretion (inowedzera kuwedzera ne2.1 nguva), inhibits TNF-α (inoderera ne58%), uye inovandudza chirwere chinoputika.
Allergy Intervention: Inoderedza serum IgE mazinga ne37% uye inoderedza kuitika kweatopic dermatitis mucheche nevana vaduku (OR = 0.42).
3. Neuropsychiatric Modulation
Gut-Brain Axis Effects: Inomutsa vagus nerve nzira, kuderedza kushambira kwekumanikidzika nguva yekusafamba mumakonzo ane hukama ne53%. Metabolic Intervention: SCFAs (short-chain chain fatty acids) inogadzirisa GABA receptors uye inovandudza kurara kwemakonzo kuenzanisa kusagadzikana kusingaperi.
4. Kudzivirira Kwezvirwere uye Kurapa
Metabolic Syndrome: Yakaderedza kutsanya kweglucose yeropa ne1.8 mmol / L kune varwere vane chirwere cheshuga chechipiri uye yakavandudza HOMA-IR index ne42%.
Adjuvant Cancer Therapy: Kusanganiswa ne5-FU kwakawedzera mwero wekupona kwemakonzo ane cancer cancer ne31% uye yakaderedza bundu vhoriyamu ne54%.
• Chii ChinoshandiswaBifidobacteria Longum ?
Bifidobacterium longum iri kutyora miganhu yechinyakare, ichigadzira nzvimbo nhanhatu dzekushandisa:
1. Indasitiri yezvokudya
Zvigadzirwa zvemukaka zvakaviriswa: Kana zvakasanganiswa neStreptococcus thermophilus, inowedzera huso hweyoghuti neka 2.3 uye inowedzera hupenyu hwesherufu kusvika kumazuva makumi mana nemashanu.
Chikafu chinoshanda: Kuwedzera 5 × 10 ^ 9 CFU / g kumabhawa ezviyo kunowedzera mafambiro ekufamba kubva ku2.1 kusvika ku4.3 nguva pasvondo muvanhu vane kuvimbiswa.
2. Pharmaceuticals
Over-the-counter (OTC) mishonga:Bifidobacterium longumkatatu mhenyu mabhakitiriya capsules (Lizhu Changle) ane kutengesa kwepagore kunodarika 230 miriyoni mabhokisi uye ane 89% anoshanda mukurapa manyoka.
Biologics: Sublingual inokurumidza-kunyungudika mapiritsi anowedzera probiotic colonization kumhanya katatu uye akagamuchira FDA Fast Track mvumo.
3. Zvekurima neKudyisa
Zvipfuyo nehuku: Kuwedzera 1 × 10 ^ 8 CFU/kg yekudya kunoderedza manyoka munguruve ne67% uye kunowedzera kushandurwa kwekudya ne15%. Kudzivirirwa kweChirimwa: Kudyara kweRhizosphere kwakaderedza wilt yematomatisi ne42% uye yakawedzera goho ne18%.
4. Cosmetic Ingredients
Kugadziriswa kweBarriers: 0.1% yebhakitiriya inobvisa yakaderedzwa ganda TEWL (transepidermal mvura kurasikirwa) ne38%, inowana EU ECOCERT chitupa.
Anti-Kukwegura Zvikumbiro: Zvakasanganiswabifidobacterium longumnemapeptides, yakaderedza kudzika kwema periorbital wrinkles ne29%, ichiwana special-use cosmetic certification kubva kuJapan Ministry of Health, Labor and Welfare.
5. Environmental Technology
Kugadziriswa kweWastewater: Ammonia nitrogen degradation performance ye 78% yakawanikwa, ichideredza kugadzirwa kwemarara ne35%.
Biofuel: Kubudirira kweAcetic acid yekugadzira kwakawedzera kusvika 12.3 g/L, ichideredza mutengo ne40% zvichienzaniswa nemaitiro echinyakare.
6. Pet Health
Chikafu chePet: Kuwedzera 2 × 10 ^ 8 CFU / kg kune chikafu chembwa chakavandudza fecal scores ne61% uye kuderedza manyoka.
Behaviour Modification: Kupfapfaidza kwakaderedza kushushikana kwekuparadzana uye kudzikisa hukasha ne54%.
• Newgreen Supply High QualityBifidobacteria LongumUpfu
Nguva yekutumira: Jul-29-2025
