Andrographis Paniculata Extract: ine simba Antibacterial uye Anti-Inflammatory Herbal Ingredient.

●Chii Andrographis Paniculata Extract?

Andrographis paniculata, inozivikanwawo se "mufaro wenguva imwe" uye "uswa hunovava", chirimwa chegore negore chemhuri yeAcanthaceae. Inowanikwa kuSouth Asia seIndia neSri Lanka, uye ikozvino yakaparadzirwa zvakanyanya munzvimbo dzine hunyoro uye dzinopisa dzakadai seGuangdong neFujian kuChina. Chirimwa chose chinonaka chinovava zvakanyanya, chine hunde mativi, mashizha akatarisana, uye nguva yekutumbuka yaNyamavhuvhu-Gunyana. Mushonga wechiChinese wechinyakare unoshandisa mhedzisiro yawo yekubvisa kupisa uye kubvisa, kutonhora kweropa uye kuderedza kuzvimba kurapa dzihwa, fivha, manyoka, maronda uye kurumwa nenyoka. Indasitiri yemazuva ano inobvisa zvinhu zvinoshanda kubva pamazinde uye mashizha kuburikidza ne supercritical CO₂ kudhirowa uye bio-enzymatic hydrolysis tekinoroji kugadzira yakajairwa poda ine andrographolide yemukati ye8% -98%, ichisimudzira kukwidziridzwa kwayo kubva kune yechivanhu mishonga yemakwenzi kuenda kune dzimwe nyika mbishi.

The core active ingredients yeAndrographis Paniculata Extractsndiwo diterpenoid lactone makomisheni, anoverengera 2% -5%24, kunyanya kusanganisira:

1.  Andrographolide:molecular formula C₂₀H₃₀O₅, inoverengera 30% -50%, ndiyo inonyanya kushanda chinhu cheantibacterial uye anti-inflammatory.
2.  Dehydroandrographolide:molecular formula C₂₀H₂₈O₄, nzvimbo yakanyunguduka 204 ℃, ine yakakosha anti-bundu chiitiko.
3. 14-Deoxyandrographolide:molecular formula C₂₀H₃₀O₄, ine simba rakatanhamara kurwisa leptospirosis.
4. Neoandrographolide:molecular formula C₂₆H₄₀O₈, yakanaka solubility yemvura, yakakodzera kugadzirira nemuromo.

Mukuwedzera, flavonoids, phenolic acids uye mafuta anoputika zvikamu synergistically zvinowedzera antioxidant uye immunomodulatory mabasa.

●Ndezvipi Zvakanakira Andrographis Paniculata Extract?

1. Immunomodulation Uye Anti-Infection

Antibacterial uye antiviral: Andrographolide ine inhibition rate inopfuura 90% paStaphylococcus aureus uye Shigella dysentery, uye kushanda kwayo kwekiriniki mukurapa bacillary dysentery kunofananidzwa nechloramphenicol. Mvura yaro yemvura inogona kuderedza kuitika kwefuruwenza ne30% uye kupfupisa nguva yechando ne50%.

Immunoenhancement: Nekuita macrophages uye T lymphocytes, inogona kuwedzera huwandu hweCD4⁺ lymphocytes muvarwere veHIV (data rekiriniki: 405→ 501 / mm³, p = 0.002).

2. Anti-Tumor Uye Angiogenesis Inhibition

Yakananga anti-tumor: Dehydroandrographolide inogona kutadzisa kukura kweW256 yakasimwa mamota uye inhibit cancer maseru kupararira nenzira inoenderana nedosi.

Anti-angiogenesis: Andrographolide inovhara tumor angiogenesis nekuderedza VEGFR2 kutaura uye kuvharidzira ERK/p38 nzira yekusaina, ine IC₅₀ ye100-200μM.

3. Metabolism Uye Organ Dziviriro

Kudzivirirwa kwechiropa uye kuderedza lipid: Andrographolide inochengetedza glutathione mazinga uye inoderedza malondialdehyde (MDA) mu carbon tetrachloride kukuvara kwechiropa muenzaniso ne40%, iyo iri nani kupfuura silymarin.

Kudzivirirwa kwemoyo: Inogadzirisa nitric oxide / endothelin chiyero, inonotsa atherosclerosis, uye inoderedza mazinga eropa lipid mukuyedza tsuro.

4. Anti-Inflammatory Uye Antioxidant

Mvura yakasvibirira yehunde ine simba rakasimba rekutsvaira mahara radicals (IC₅₀ = 4.42μg / mL), iyo inopfuura 4 nguva yakawanda kupfuura synthetic antioxidants uye inokodzera zvirwere zvisingaperi zvinopisa.

●Ndeapi Maapplication EAndrographis Paniculata Extract ?

1. Mushonga Uye Kurapwa Kwechipatara

Anti-infective drugs: inoshandiswa kurapa mabhakitiriya manyoka, jekiseni remabayo uye nemuromo kugadzirira pharyngitis, ine kiriniki yekurapa inodarika 85%.

Anti-tumor yakanangana nemishonga: Andrographolide derivative "Andrographine" yapinda muChikamu chechipiri chekiriniki miedzo yeleukemia nemamota akasimba.

Chirwere chechirwere chechirwere: adjuvant kurapwa kwechirwere cheshuga retinopathy (0.5-2mg / kg / zuva) uye rheumatoid arthritis (1-3mg / kg / zuva).

2. Kuchengeta Mhuka Uye Kuberekera Green

Alternative antibiotics: Compound Andrographis paniculata feed additives inoderedza manyoka enguruve uye inowedzera kurarama kwebroiler; kuwedzera 4% kubvisa kune carp feed, chiyero chekuwedzera uremu chinosvika 155.1%, uye chiyero chekushandura chikafu chinogadziriswa kusvika 1.11.

Kudzivirirwa nekudzivirira zvirwere: Jekiseni reAndrographis paniculata rinorapa mabayo enguruve uye enteritis, nechiyero chekurapa che90% uye chiyero chekufa kwe10%.

3. Hutano Kudya Uye Daily Chemicals

Chikafu chinoshanda: Andrographis paniculataextractcapsules (200mg pazuva) inotangwa mumisika yeEurope neAmerica yekudzivirira kwekudzivirira uye kudzivirira kutonhora.

Zvigadzirwa zvekuchengetedza ganda: Wedzera kune anti-kuzvimba essences uye sunscreens kuti ubvise kukuvadzwa kweUV uye kutsvuka kweganda rinonzwa.

4. Mabhindauko Muminda Ichiri Kusimukira

Anti-angiogenic mishonga: Kuvandudzwa kwegadziriro dzakanangwa dzemamota uye chirwere cheshuga retinopathy chave nzira yakakosha yekugadzira biology.

Hutano hwemhuka dzemhuka: Anti-inflammatory uye immunomodulatory supplements yembwa nekatsi zvinotangwa mumusika weNorth America, nekukura kwepagore kwe35%.

●NEWGREEN SupplyAndrographis Paniculata ExtractUpfu