Sodium 3-Hydroxybutyrate: Inyungu, Porogaramu nibindi

●Niki Sodium 3-Hydroxybutyrate ?

Sodium 3-hydroxybutyrate (sodium β-hydroxybutyrate, BHB-Na) ningingo nyamukuru yumubiri wa ketone metabolism. Bibaho bisanzwe mumaraso ninkari, cyane cyane mubihe inzara cyangwa karubone nkeya. Imyiteguro gakondo ishingiye kuri hydrolysis ya 3-hydroxybutyric acide est est (methyl ester / ethyl ester) na hydroxide ya sodium, ariko bisaba ko hajyaho ibinyabuzima byongera imbaraga, biganisha ku nzira igoye, kwinjiza amazi neza no kwegeranya ibicuruzwa, hamwe n’umuti usigaye ushobora kugira ingaruka ku mutekano w’ibikorwa by’ubuvuzi.

Kugeza ubu, ibigo bimwe na bimwe byateye intambwe mu guhanga udushya: umwanda wa acide crotonic ugenzurwa munsi ya 16ppm hakoreshejwe uburyo bwa methanol-acetone ucamo ibice, kandi ubuziranenge bwiyongereye kugera kuri 99.5%, bujuje ubuziranenge;

Tekinoroji yintambwe imwe yo gukanika spray ikoresha 160 air umwuka ushyushye kugirango uhindure neza amazi ya reaction muri microcrystal spherical, hamwe nibicuruzwa birenga 95%. Ikwirakwizwa rya X-ray ryerekana impinga 17 ziranga (2θ = 6.1 °, 26.0 °, nibindi), kandi ituze ryimiterere ya kirisiti irikubye inshuro 3 ugereranije nibikorwa gakondo, bikemura burundu ikibazo cyo kwinjiza amazi.

●NikiInyunguBya Sodium 3-Hydroxybutyrate ?

Nka "molekile ya super lisansi", sodium 3-hydroxybutyrate itanga ingufu binyuze mumyanya yubwonko bwamaraso, kandi imikorere yayo ya physiologique yakozweho ubushakashatsi bwimbitse mumyaka yashize:

Amabwiriza ya Metabolic:Muburyo bwa diyabete, itezimbere insuline. Igipimo kimwe (0.2 mg / kg) kirashobora kongera umwijima glycogene synthesis 40%;

Neuroprotection:Ubushakashatsi bwerekanye ko inkomoko ya 3-hydroxybutyrate methyl ester ishobora gukora imiyoboro ya calcium yo mu bwoko bwa L, ikongerera intungamubiri za calcium ion mu ngirabuzimafatizo ya glial 50%, kandi ikabuza apoptose selile 35%, itanga inzira nshya yo kuvura indwara ya Alzheimer;

Kurwanya Kurwanya no Kurwanya:Mugabanye lipide peroxide nubwoko bwa ogisijeni ikora (ROS), igabanya ububabare bwimitsi nyuma yimyitozo ngororamubiri, kandi imikorere yabakinnyi yihanganira kwiyongera 22% nyuma yinyongera.

●NikiGusabaByaSodium 3-Hydroxybutyrate ?

1. Inganda zubuzima: Intandaro yubukungu bwa Ketogenic

Gucunga ibiro: nkibintu byingenzi byongera ketogenic, bitera umwijima gukora neza.

Imirire ya siporo: ibinyobwa bya electrolyteSodium 3-Hydroxybutyratehiyongereyeho amashami ya aminide acide irashobora kugumana amaraso ya ketone hejuru ya 4mM nyuma yo gukora siporo no kugabanya igihe cyo gukira imitsi 30%.

2. Urwego rwubuvuzi: Ibyiringiro bishya byindwara za Neurodegenerative

Kuvura igicuri: bifatanije na anticonvulsants birashobora kugabanya inshuro 30 zifata inshuro 30, kandi hatangijwe ibizamini byo kwa muganga icyiciro cya III;

Sisitemu yo gutanga intego: Cy7 fluorescent yanditseho probe igera mugukurikirana vivo, kandi amashusho yegeranye na infragre yerekana ko ikungahaye muri hippocampus mugihe cyamasaha 2, itanga ubwikorezi bwo kuyobora ibiyobyabwenge byubwonko.

3. Ibikoresho bya siyansi: Urufunguzo rwibinyabuzima rwo guca umwanda wera

Ibinyabuzima byangiza ibinyabuzima: Gukoporora hamwe na polyester ya aromatiya kugirango ikore PHB (poly 3-hydroxybutyrate), hamwe no gushonga kwa 175 ° C hamwe na ogisijeni ya 1/10 cya PET gusa. Irashobora kwangirika rwose mubutaka bwa anaerobic muminsi 60. Guangdong Yuanda New Materials Co., Ltd. yageze ku musaruro rusange w’inganda;

Gusenya firime yubuhinzi: PE mulch hamwe na 5% sodium 3-hydroxybutyrate yongeyeho, itakaza imiterere yubukanishi ubwayo nyuma yo kuyikoresha, kandi ikaba idafite ibisigazwa bya microplastique nyuma yo gufumbira.

●NEWGREEN Tanga ubuziranengeSodium 3-Hydroxybutyrate Ifu