●NikiL-Citrulline?
L. Umusaruro ugezweho winganda uboneka cyane muburyo bubiri:
Gukuramo bisanzwe: bitandukanijwe nibihingwa bya cucurbitaceae nka watermelon na cucumber, ariko bifite ubushobozi buke nigiciro kinini;
Biosynthesis: ibisekuruza bya catalitiki muri cycle ya urea ukoresheje ornithine na karbamoyl fosifate nka substrate, cyangwa guhinduranya okiside ya arginine ukoresheje synthase ya nitric oxyde (NOS).
Imiterere yumubiri nubumaraBya L-Citrulline :
Ibyiza no gukemuka: ifu ya kirisiti yera, uburyohe busharira gato; byoroshye gushonga mumazi (solubility 200g / L, 20 ℃), hafi yo kudashonga mumashanyarazi nka Ethanol na ether;
Ibikoresho byiza: kuzunguruka byihariye + 24.5 ° ~ + 26.8 ° (c = 8, 6N HCl), nicyo kimenyetso cyingenzi cyo kumenya ukuri;
Inenge zihamye: zumva urumuri nubushyuhe, gushonga ni 214-222 ℃ (uburyo butandukanye bwa kirisiti), byoroshye kubora hejuru ya 100 ℃; bigomba gufungwa no kubikwa kure yumucyo no mubushyuhe buke (0-5 ℃);
Ibipimo ngenderwaho byo kugenzura ubuziranenge: ibicuruzwa byo mu rwego rwa farumasi bisaba ibyuma biremereye ≤10ppm, ibirimo amazi ≤ 0,30%, hamwe n’ibisigara byo gutwika ≤0.10% (igipimo cya AJI92).
●NikiInyunguByaL-Citrulline ?
Agaciro kingenzi ka L-citrulline iri mubushobozi bwayo bwo guhinduka muri arginine no kurekura aside nitide (OYA), bityo igakora ingaruka nyinshi zifatika:
Kurinda umutima
Kuraho umuvuduko w'amaraso no kunoza amaraso binyuze muri NO-medrated vascular yoroshye imitsi kuruhuka;
Ubushakashatsi bwakozwe na kaminuza ya Texas A&M yo muri Amerika bwemeje ko uburyo bwabwo bwo kuvura imitsi busa na "Viagra naturel", aho iterambere rya 40% ryatewe no kudakora neza kandi nta ngaruka mbi z’ibiyobyabwenge.
Metabolism no Kugenga Immune
Guteza imbere umwijima urea cycle, kwihutisha metabolisme ya ammonia, no kugabanya ammonia yibanze;
Ongera ibikorwa bya macrophage kandi wongere ubushobozi bwa virusi (nkigipimo cya virusi ya grippe cyiyongereyeho 35%).
Imikorere ya Neru na moteri
Kurenga inzitizi yubwonko bwamaraso kugirango wongere OYA murwego rwubwonko kandi wongere ubushobozi bwo kugarura amakuru yibuka;
Gutesha agaciro ubwoko bwa ogisijeni (ROS) buterwa no gukora siporo no kongera igihe cyo kwihanganira imitsi 22%.
●NikiGusabaOf L-Citrulline?
Inganda zubuzima:
Ibicuruzwa byimirire ya siporo: byiyongereye hamwe na acide aminide acide, amaraso ya ketone nyuma yimyitozo ngororamubiri ikomeza hejuru ya 4mM, kandi igihe cyo gukira imitsi kigabanukaho 30% (umugabane w isoko ku isi muri 2024 ni 45%);
Imikorere yimibonano mpuzabitsina itezimbere: citrulline irashobora guteza vasodilasiya no kunoza imikorere mibi
Inganda zikora ibiribwa:
Kubungabunga ibidukikije: kubuza ikwirakwizwa rya mikorobe mu bicuruzwa by’inyama zo mu mazi, kandi umubare rusange w’abakoloni ba salmon ikonjesha ugabanukaho 90%;
Inyongeramusaruro zikora: "L-Citrulline + γ-aminobutyric aside" yogurt ikora, igenzura icyarimwe umuvuduko wamaraso no guhangayika.
3. Biomedicine:
Kuvura indwara ya Alzheimer: kora inzira ya cAMP / PI3K-Akt, wongere imvugo yibintu bikomoka mu bwonko biva mu bwonko (BDNF), kandi utezimbere ubushobozi bwo kwiga no kwibuka imbeba ntangarugero 40%;
Sisitemu yo gutanga Gene: nka pDNA nanocarrier, uburyo bwo kwanduza bwikubye inshuro 100 ugereranije na liposomes, kandi bizinjira mu cyiciro cya mbere cy’amavuriro yo kuvura ibibyimba mu bwonko mu 2025.
4. Guhanga udushya two kwisiga
Ufatanije na polysaccharide moisturizers, imikorere yo kuvura uruhu rwumye irenga 80%;
Irabuza kwanduza ibimenyetso byimitsi muri pruritis dermatitis kandi igasana imikorere ya bariyeri ya stratum corneum.
●Icyatsi gishya gitanga ubuziranengeL-CitrullineIfu
Igihe cyo kohereza: Nyakanga-16-2025
