●Niki Sodium ya Chondroitin?
Sodium ya Chondroitin Sulfate (CSS) ni mucopolysaccharide ya acide isanzwe ifite imiti ya C₄₂H₅₇N₃Na₆O₄₃S₃X₂ (uburemere bwa molekuline bungana na 1526.03). Ikurwa cyane cyane mubice bya karitsiye yinyamaswa nkingurube, inka, ninyanja. Imiterere ya molekile yayo igizwe no guhinduranya aside D-glucuronic na N-acetylgalactosamine, irimo ibice 50-70 bya disaccharide kandi bitwara amatsinda angana na acetyl na sulfate. Ibikoresho fatizo byo hejuru biracyashingira ku bushyuhe buke buke bwa karitsiye, muri yo amagufwa y’ingurube n’amagufwa yo mu mazuru hagati ni yo nzira ya mbere yo kuvoma mu rwego rw’ubuvuzi bitewe na sulfate nyinshi ya chondroitine A / C (bingana na 24% byuburemere bwumye).
Uburyo bwo kuvomaof Sodium ya Chondroitin:
Gukuramo gakondo bisaba inzira enye zuzuye:
Alkaline deproteinisation: Shira karitsiye mumuti wa sodium hydroxide ya 2% hanyuma ukuramo hamwe no gukurura ubushyuhe bwicyumba
Isuku ya Enzymatique: Hydrolyze hamwe na enzymes pancreatic enzymes kuri 53-54 ℃ mumasaha 7, hamwe na adsorb umwanda hamwe na karubone ikora;
Imvura ya Ethanol: Hindura pH kuri 6.0 hanyuma wongereho 75% Ethanol kugirango imvura igwe;
Umwuma no gukama: Karaba na Ethanol ya anhydrous hanyuma ukame muri vacuum kuri 60-65 ℃.
Kuvugurura inzira: Ibigo byinshi byatangije ibikoresho bishya byubuvuzi byo mu rwego rw’ubuvuzi, bifashishije karitsiye ya shark mu kuyikuramo, gutsinda virusi itangiza virusi hamwe na aseptic, hamwe n’ibizamini bya pyrogen na cytotoxicity kugira ngo byuzuze amahame mpuzamahanga.
●NikiInyunguBya Sodium ya Chondroitin ?
1. Ibyingenzi byo kuvura indwara
Gusana Cartilage: gushishikariza chondrocytes guhuza syntagen, kunoza imitsi ya sinovique viscoelasticitike, no kugabanya ubwumvikane buke ku barwayi ba osteoarthritis 40%;
Kurwanya anti-inflammatory analgesia: kubuza fosifolipase A2 na matrix metalloproteinase, kugabanya umusaruro w’abunzi batera umuriro nka prostaglandine, kandi igipimo cyo kugabanya ububabare kigera kuri 90% nyuma yibyumweru 12 bivurwa.
2. Kugenzura Sisitemu Yumutima
Kugabanya lipide no kurinda imitsi: kuvanaho lipide yabitswe kurukuta rwamaraso, kugabanya cyane cholesterol ya plasma, no kugabanya ubuso bwa plaque ya aterosklerotike 60%;
Anticoagulation: Igikorwa cyo kurwanya anticoagulant yaSodium ya Chondroitin ni inshuro 0.45 / mg ya heparin, kandi trombose irindwa binyuze muri sisitemu ya fibrinogen.
3. Gutabara Indwara-Sisitemu
Kurinda kumva: gusana imisatsi ya cochlear, kandi igipimo cyiza cyo gukumira ibipfamatwi cyatewe na streptomycine kirenga 85%;
Gukoresha amaso: kunoza metabolisme y'amazi ya corneal, no kongera amarira y'abarwayi bafite amaso yumye 50%;
Ubushobozi bwo kurwanya ibibyimba: sulfate ikomoka kuri shark ikomoka kuri shark ibuza metastasis ya selile kanseri muguhagarika ikibyimba angiogenez.
●NikiGusabaOf Sodium ya Chondroitin?
1. Isoko ryiganje mu murima wa farumasi
Ubuvuzi buhuriweho hamwe: Imyiteguro hamwe na glucosamine ihwanye na 45% byisoko ryibiyobyabwenge bya osteoarthritis kwisi yose
Imiti yumutima nimiyoboro: Gutanga umunwa burimunsi 0,6-1.2g birashobora kugabanya umuvuduko wimpfu zindwara z'umutima.
2. Ibikoresho byubuvuzi nubuhanga bwiza bwubuvuzi
Ophthalmic viscoelastics: Ubuziranenge-bwinshisodium ya chondroitinikoreshwa mu kubaga cataracte kugirango irinde igipimo cyo kubaho kwa selile corneal endothelial selile zirenga 95%;
Ubuvuzi bwuzuza ubuvuzi: burashobora gukoreshwa nkibikoresho fatizo byo mu rwego rwa sterile yo gutera inshinge zamazi no kuzuza dermal, kandi bigateza imbere imikorere ya kolagen 70%;
Gukiza ibikomere: gel 0,2% yihutisha gukira ibisebe byamaguru bya diyabete, kandi kugabanuka kwikomere muminsi 21 bigera kuri 80%.
3. Kwagura ibicuruzwa byumuguzi bikora
Kwita ku ruhu no kurwanya gusaza: Kwiyongera kuri cream birashobora kongera ubuhehere bwuruhu ku 16% kandi bikagabanya ubujyakuzimu bw’iminkanyari 29%;
Ibiryo byubuzima: Isosiyete yatangije "CSS + amavuta y amafi" ikora bombo ikora icyarimwe kugirango igabanye icyarimwe guhuza hamwe nurwego rwa lipide.
●Icyatsi gishya gitanga ubuziranenge Sodium ya Chondroitin Ifu
Igihe cyo kohereza: Kanama-12-2025
